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| Status |
Public on Dec 31, 2017 |
| Title |
Analysis of gene expression changes in B cells upon Csnk2b conditional deletion |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Protein kinase CK2, a tetrameric enzyme composed by 2 catalitic alpha and 2 regulatory beta subunits, supports malignant B cell lymphocyte growth, however, its physiological role in B lymphopoiesis is still unknown. With this analysis we intended to assess if CK2 plays a role in peripheral B cell development and to do this we compared the mRNA from Csnk2b+/+ (WT) and Csnk2b-/- (KO) purified splenic B cells. Here we report a list of all genes identified as differentially expressed between WT and KO B cells.
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| Overall design |
Examination of splenic B cell mRNA profiles of 8-weeks-old Csnk2b+/+ (n=3) and Csnk2b-/- (n=3) mice generated with …
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| Contributor(s) |
Mandato E, Zaffino F, Casellato A, Pizzi M, Macaccaro P, Vitulo N, Canovas Nunes S, Quotti Tubi L, Zumerle S, Manni S, Filhol-Cochet O, Boldyreff B, Siebel CW, Viola A, Trentin L, Valle G, Semenzato G, Piazza F |
| Citation(s) |
36713383 |
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| Submission date |
Oct 24, 2016 |
| Last update date |
Feb 07, 2023 |
| Contact name |
Nicola Vitulo |
| E-mail(s) |
nicola.vitulo@univr.it
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| Organization name |
University of Verona
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| Department |
Department Biotechnology
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| Street address |
Ca' Vignal 1, Strada Le Grazie 15
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| City |
Verona |
| State/province |
Verona |
| ZIP/Postal code |
37134 |
| Country |
Italy |
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| Platforms (1) |
| GPL18635 |
Ion Torrent Proton (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA350257 |
| SRA |
SRP091968 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE89082_Matrix_norm.txt.gz |
185.4 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Processed data are available on Series record |
| Raw data are available in SRA |
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