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Series GSE8916 Query DataSets for GSE8916
Status Public on Aug 01, 2008
Title Gene expression changes with inducible expression of activated ras and ras effector domain mutants
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The goals of this study were to identify gene transcription changes in cells expressing activated H-RasV12 or activated versions of the ras effector domain mutants RasV12G37, RasV12S35, and RasV12C40 for the purpose of identifying common or unique transcription alterations in cells transformed by different ras signal transduction pathways.
Keywords: genetic modification design
Overall design HME16C mammary epithelial cells infected with pLRT control vector, or H-RasV12-, V12G37-, V12S35-, or V12C40-expressing vectors were each treated with 250ng/mL doxycycline and total RNA prepared at two separate times to give two biological replicates. Then dye swap experiments were performed with each biological replicate.
Citation(s) 18597688
Submission date Aug 30, 2007
Last update date Aug 29, 2019
Contact name Kathleen Kelly
Phone 3014354652
Fax 3014354655
Organization name National Institutes of Health
Department Cancer and Cell Biology Branch
Lab Kelly
Street address 37 Convent Drive
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL1528 NCI/ATC Hs-OperonV2
Samples (16)
GSM225968 G37 vs. pLRT - repeat 1 - mAdbID:48887
GSM225969 G37 vs. pLRT - repeat 2 - mAdbID:48888
GSM225970 G37 vs. pLRT - repeat 3 - mAdbID:49118
BioProject PRJNA102317

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8916_RAW.tar 32.8 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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