|
| Status |
Public on Jan 01, 2017 |
| Title |
Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-seq within OCN-Cre;Cdc73flox/flox osteoblasts showed that loss of Cdc73 led to a derepression of osteoblast-specific genes, specifically those for collagen and other bone matrix proteins.
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| |
|
| Overall design |
RNA-seq of Flow-sorted calvarial osteoblasts of C57Bl/6J mice
|
| |
|
| Contributor(s) |
Droscha C, Williams B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 05, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Casey James Droscha |
| Organization name |
Van Andel Institute
|
| Department |
Program for Skeletal Disease and Tumor Microenviroment
|
| Lab |
Cell Signaling & Carcinogenesis
|
| Street address |
333 Bostwick Ave.
|
| City |
Grand Rapids |
| State/province |
Michigan |
| ZIP/Postal code |
49503 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA356286 |
| SRA |
SRP094569 |
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