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Series GSE9103 Query DataSets for GSE9103
Status Public on Nov 01, 2007
Title Skeletal Muscle Transcript Profiles in Trained or Sedentary Young and Old Subjects
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Aging is associated with mitochondrial dysfunction and insulin resistance. We conducted a study to determine the role of long-term vigorous endurance exercise on age-related changes in insulin sensitivity and various indices of mitochondrial functions.
Keywords: The effect of excises in young and old human subjects by transcription profiling
 
Overall design Skeletal muscle transcript profiling was done using Vastus Lateralis muscle biopsy samples from 10 young sedentary (YS), 10 older sedentary (OS), 10 young trained (YT) and 10 older trained (OT) men and women. Note that YT2, YS1, and OT1 didn't pass the Quality Control Step of dChip (high array/single outliers). Sedentary subjects exercised less than 30 min/day, twice per week. Trained subjects performed ≥ 1 hour cycling or running 6 days/week over the past 4 years.
 
Contributor(s) Asmann YW, Nair KS, Lanza IR, Short DK, Short KR, Bigelow ML, Joyner MJ
Citation(s) 18716044
Submission date Sep 19, 2007
Last update date Mar 25, 2019
Contact name Yan W. Asmann
E-mail(s) asmann.yan@mayo.edu
Organization name Mayo Clinic
Street address 4500 San Pablo Road South
City Jacksonville
State/province FL
ZIP/Postal code 32224
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (40)
GSM230387 Old sedentary subject, biological replicate (OS1)
GSM230388 Old sedentary subject, biological replicate (OS2)
GSM230389 Old sedentary subject, biological replicate (OS3)
Relations
BioProject PRJNA102631

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE9103_RAW.tar 153.2 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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