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| Status |
Public on May 29, 2018 |
| Title |
Epigenetic signature of extended critical period learning |
| Organism |
Taeniopygia guttata |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
We used a combination of ChIPseq, RNAseq, bioinformatic analysis, and molecular biology in the auditory forebrain, a brain area required for tutor song memorization to elucidate the role epigenetics plays in song learning. These analyses revealed thousands of genes were differentially marked by PTMs under these two conditions, indicating greater transcription in the birds with extended learning.
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| Overall design |
H3K4me3, H3K27me3, H3K9me3 and Pol II ChIP-seq was performed on p65 Tutor and Isolate and p32 Zebra Finch Songbird
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| Contributor(s) |
London SE, Kelly TK |
| Citation(s) |
29720411 |
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| Submission date |
Dec 10, 2016 |
| Last update date |
May 29, 2018 |
| Contact name |
Sarah E London |
| E-mail(s) |
london@uchicago.edu
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| Organization name |
University of Chicago
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| Street address |
940 E 57th Street
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| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60637 |
| Country |
USA |
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| Platforms (1) |
| GPL22780 |
Illumina NextSeq 500 (Taeniopygia guttata) |
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| Samples (23)
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| Relations |
| BioProject |
PRJNA356945 |
| SRA |
SRP094885 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE91399_RAW.tar |
1.2 Gb |
(http)(custom) |
TAR (of BED, BW) |
SRA Run Selector |
| Processed data provided as supplementary file |
| Raw data are available in SRA |
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