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Status |
Public on Aug 02, 2017 |
Title |
Genome-wide binding of MYCN protein in MYCN-amplified neuroblastoma cell lines |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
The MYCN locus is amplified in about half of high-risk neuroblastoma tumors. To identify genomic loci occupied by MYCN protein in the MYCN-amplified neuroblastoma cell lines NGP, Kelly and NB-1643, we performed chromatin immunoprecipitation coupled with Next-Generation Sequencing (ChIP-seq) using an anti-MYCN antibody.
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Overall design |
Identification of MYCN occupancy throughout the genome of MYCN-amplified neuroblastoma cells.
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Contributor(s) |
Sussman RT, Rathi KS |
Citation(s) |
28898695, 32286315 |
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Submission date |
Feb 10, 2017 |
Last update date |
Apr 27, 2020 |
Contact name |
John M Maris |
E-mail(s) |
Maris@email.chop.edu
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Organization name |
Children's Hospital of Philadelphia
|
Street address |
3501 Civic Center Blvd, CTRB
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City |
Philadelphia |
State/province |
Pennsylvania |
ZIP/Postal code |
19104 |
Country |
USA |
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Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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Samples (6)
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Relations |
BioProject |
PRJNA374035 |
SRA |
SRP099215 |