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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Feb 28, 2017 |
| Title |
Transcriptome analysis of liver tissue in HBV - associated liver fibrosis mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Purpose:Next-generation sequencing (NGS) were performed to investigate the differentially expressed molecular signature that were associated with HBV-mediated liver fibrosis
Method: four cDNA libraries of separated groups ranging from 1, 3, 6-months post injection were constructed in the HBV (-) and analyzed using RNA-seq.
results: Sequencing of the clean reads resulted in ~29–40 million reads per sample, for a total of ~438 million reads across 12 samples. Specifically, an average of 16,782, 17,088, 18,701, and 19,364 genes were identified in the HBV (+) mouse (1, 3, 6-months post injection) and HBV (-) mouse (control groups), respectively.
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| Overall design |
Analysis mRNA profiles of HBV(+) mouse samples from 1, 3, 6-months post injection and HBV(-) mouse samples.
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| Contributor(s) |
Kan F, Li W |
| Citation(s) |
28830339 |
| Submission date |
Feb 27, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Fangming Kan |
| E-mail(s) |
kfm86@163.com
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| Organization name |
MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences
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| Street address |
Dongdansantiao
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| City |
Beijing |
| ZIP/Postal code |
100176 |
| Country |
China |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA377098 |
| SRA |
SRP100778 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE95424_Group_1Month-VS-Control_DE_significant.raw.xls.gz |
46.3 Kb |
(ftp)(http) |
XLS |
| GSE95424_Group_3Month-VS-Control_DE_significant.raw.xls.gz |
323.9 Kb |
(ftp)(http) |
XLS |
| GSE95424_Group_6Month-VS-Control_DE_significant.raw.xls.gz |
288.9 Kb |
(ftp)(http) |
XLS |
| GSE95424_Rpkm.xls.gz |
1.0 Mb |
(ftp)(http) |
XLS |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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