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Series GSE97113 Query DataSets for GSE97113
Status Public on Feb 13, 2019
Title Sex-biased hippocampal pathology in the 5XFAD mouse model of Alzheimer's disease: A multi-omic analysis
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Numerous neurological disorders, including Alzheimer's disease, display a sex-biased prevalence. To identify molecular correlates of this sex bias, we investigated sex-differences in molecular pathology in the hippocampus using the 5XFAD mouse model of Alzheimer's disease during early stages of disease progression (1, 2, and 4 months of age).
Overall design Hippocampal mRNA from 1, 2, and 4 month old male and female 5XFAD mice were analyzed by RNA sequencing of 5 biological replicates using an Illumina HiSeq 2500
Contributor(s) Bundy JL, Vied C, Dawn-Badger C, Nowakowski RS
Citation(s) 30291623
Submission date Mar 28, 2017
Last update date May 15, 2019
Contact name Joseph Ligon Bundy
Organization name Florida State University
Department Department of Biomedical Sciences
Lab Dr. Richard Nowakowski
Street address 1115 W Call St
City Tallahassee
State/province FL
ZIP/Postal code 32304
Country USA
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (30)
GSM2551892 1M F1 AD
GSM2551893 1M F2 AD
GSM2551894 1M F3 AD
BioProject PRJNA380737
SRA SRP102581

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Supplementary file Size Download File type/resource
GSE97113_5XFAD_counts_and_FPKM.xlsx 14.2 Mb (ftp)(http) XLSX
GSE97113_Supplemental_file_1_genelists.xlsx 21.2 Mb (ftp)(http) XLSX
GSE97113_Supplemental_file_2_QPCR_validation.xlsx 132.4 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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