|
| Status |
Public on Apr 26, 2017 |
| Title |
Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Our mouse model (Ksp-CreER/Sav1fl/fl ) offers novel insights into molecular events that are linked to fibrosis development from Sav1 loss.
|
| |
|
| Overall design |
RNAseq analysis was performed on cortex tissue from mouse kidneys with and without Sav1 loss.
|
| |
|
| Contributor(s) |
Kim WY |
| Citation(s) |
28320873 |
| |
| Submission date |
Apr 25, 2017 |
| Last update date |
Jun 30, 2020 |
| Contact name |
William Y. Kim |
| E-mail(s) |
william_kim@med.unc.edu
|
| Organization name |
University of North Carolina at Chapel Hill
|
| Department |
Medicine and Genetics
|
| Lab |
William Kim Lab
|
| Street address |
450 West Dr.
|
| City |
Chapel Hill |
| State/province |
NC |
| ZIP/Postal code |
27599 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA384229 |
| SRA |
SRP105208 |
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