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| Status |
Public on Jun 01, 2017 |
| Title |
MiR-204-3p inhibits the production of TLR4-related cytokines in familial Mediterranean fever by targeting the PI3Kγ signaling pathway |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Our data suggest that serum miR-204-3p has a potential as a useful biomarker among patients with FMF and that miR-204-3p plays a critical role as a suppressor to regulate the production of TLR4-related cytokines by targeting PI3K signaling pathway.
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| Overall design |
The RNA was obtained from THP-1 cells after LPS stimulation. Total cellular RNA was extracted using the RNeasy Plus Mini Kit (Qiagen, Hilden, Germany). We performed the cDNA microarray using the SurePrint G3 Human GE 8x60K Microarray.
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| Contributor(s) |
Koga T, Sato T, Kawakami A |
| Citation(s) |
29294109 |
| |
| Submission date |
May 15, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Tomohiro Koga |
| E-mail(s) |
tkoga@nagasaki-u.ac.jp
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| Organization name |
Nagasaki University
|
| Street address |
1-7-1 Sakamoto
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| City |
Nagasaki |
| ZIP/Postal code |
8528501 |
| Country |
Japan |
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| Platforms (1) |
| GPL20844 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Feature Number Version] |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA386872 |
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