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| Status |
Public on Nov 01, 2017 |
| Title |
MiR-471-5p–Dependent Regulation of Phagocytosis/Autophagy-Associated Proteins |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Phagocytic clearance of apoptotic germ cells by Sertoli cells is vital for germ cell development and differentiation. Using a tissue-specific miRNA transgenic mouse model, we show that interaction between miR-471-5p and autophagy member proteins regulates clearance of apoptotic germ cells via LC3-associated phagocytosis (LAP).
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| |
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| Overall design |
Ago2 immuno-precipitation profiles of miR-471-5p–transfected Sertoli cells compared to those of scramble-transfected Sertoli cells
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| |
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| Contributor(s) |
Panneerdoss S, Rao M |
| Citation(s) |
28928467 |
| |
| Submission date |
May 31, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Yidong Chen |
| E-mail(s) |
cheny8@uthscsa.edu
|
| Phone |
2105629163
|
| Organization name |
UT Health Science Center at San Antonio
|
| Department |
Population Health Sciences
|
| Street address |
8403 Floyd Curl Drive, MSC 7784
|
| City |
San Antonio |
| State/province |
Texas |
| ZIP/Postal code |
78229 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA388658 |
| SRA |
SRP108354 |
