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| Status |
Public on Sep 06, 2017 |
| Title |
Expression data from lung metastasis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The role of PGC1alpha in breast cancer lung metastasis is largely unknown. We used expression data from lung metastasis of mice injected with PGC1alpha overexpression or control cells to understand global changes that occur upon overexpression of PGC1alpha that lead to lung metastasis.
We used expression data to understand the pathways and genes that may lead to lung metastasis in a PGC1alpha overexpression setting.
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| Overall design |
Mice were injected by tail vein with either PGC1alpha overexpressing or control cells (NMuMG-ErbB2/PGC-1alpha and NMuMG-ErbB2/VC cells ) respectively. Mice were treated with phenformin for 1 week or PBS control. Lung metastasis was isolated by laser capture microdissection.
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| Contributor(s) |
Andrzjewski S, Johnson RM, Tabariès S, Annis MG |
| Citation(s) |
28988825 |
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| Submission date |
Jun 01, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Julie St-Pierre |
| E-mail(s) |
julie.st-pierre@mcgill.ca
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| Organization name |
McGill University
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| Department |
Department of Biochemistry
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| Street address |
3655 Promenade Sir William Osler
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| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H3G 1Y6 |
| Country |
Canada |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (22)
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| This SubSeries is part of SuperSeries: |
| GSE99557 |
Expression data from a lung metastatic cell line or metastatic explants in mouse and human |
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| Relations |
| BioProject |
PRJNA388964 |
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