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| Status |
Public on Sep 06, 2017 |
| Title |
Expression data from lung metastatic explants |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The role of PGC1alpha in breast cancer lung metastasis is largely unknown. We used expression data from lung metastatic explants overexpressing PGC1alpha or control, treated with phenformin to understand global gene expression changes which occur in a PGC1alpha context and under phenformin treatment.
We used expression data to understand the pathways and genes that may lead to lung metastasis in a PGC1alpha overexpression setting.
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| Overall design |
PGC1alpha overexpressing or control explants from a lung metastatic tail vein (LMTV) assay were isolated and put into culture and treated with phenformin (100uM) for 4 days or dh20 control.
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| Contributor(s) |
Andrzjewski S, Johnson RM, Tabariès S, Annis MG |
| Citation(s) |
28988825 |
| |
| Submission date |
Jun 01, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Julie St-Pierre |
| E-mail(s) |
julie.st-pierre@mcgill.ca
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| Organization name |
McGill University
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| Department |
Department of Biochemistry
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| Street address |
3655 Promenade Sir William Osler
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| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H3G 1Y6 |
| Country |
Canada |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE99557 |
Expression data from a lung metastatic cell line or metastatic explants in mouse and human |
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| Relations |
| BioProject |
PRJNA388965 |
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