GEO help: Mouse over screen elements for information.
Status
Public on Sep 07, 2006
Title
Hela, mock, 18hr vs. Hela, MAPK14-193, AS_pos6+7_modified, 18hr
Sample type
RNA
Channel 1
Source name
HeLa
Organism
Homo sapiens
Characteristics
cell line: HeLa conditions: mock, 18hr
Extracted molecule
total RNA
Label
Cy3
Channel 2
Source name
HeLa
Organism
Homo sapiens
Characteristics
cell line: HeLa conditions: MAPK14-193, AS_pos6+7_modified, 18hr
Extracted molecule
total RNA
Label
Cy5
Description
For details please see: Jackson AL, Burchard J, Leake D, Reynolds A, Schelter J, Guo J, Johnson JM, Lim L, Karpilow J, Nichols K, Marshall W, Kvorova A, and Linsley PS. RNA (2006) 12(7):1197-1205
Data processing
Local background correction
Submission date
Sep 01, 2006
Last update date
Jul 22, 2009
Contact name
Aimee Jackson
Organization name
Regulus Therapeutics
Street address
1896 Rutherford Rd
City
Carlsbad
State/province
CA
ZIP/Postal code
92008
Country
USA
Platform ID
GPL3992
Series (1)
GSE5769
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
Data table header descriptions
ID_REF
Rosetta generated unique probe identifier
VALUE
same as UNF_VALUE but with flagged values removed: Corrected (normalized) Log10 Ratio of channels (CH2/CH1)
LOGINTENSITY
Corrected average log intensity of channels
INTENSITY1
Raw Cy3 intensity (CH1)
INTENSITY2
Raw Cy5 intensity (CH2)
PVALUE
P-value of LogRatio
QUALITY
1 - if good and non control, 0 - otherwise
UNF_VALUE
Corrected (normalized) Log10 Ratio of channels (CH2/CH1)
Data table
ID_REF
VALUE
LOGINTENSITY
INTENSITY1
INTENSITY2
PVALUE
QUALITY
UNF_VALUE
10023804644
-0.1801
-2.6033
0.0036
0.0033
8.8153e-001
1
-0.1801
10023804645
-0.0371
0.0220
1.1116
1.0177
4.3976e-001
1
-0.0371
10023804646
0.0046
-0.3986
0.3976
0.4025
9.2841e-001
1
0.0046
10023804647
0.0964
-1.7728
0.0159
0.0187
7.0592e-001
1
0.0964
10023804648
0.0035
-0.4796
0.3301
0.3328
9.3887e-001
1
0.0035
10023804649
0.0340
-1.5937
0.0249
0.0263
8.3557e-001
1
0.0340
10023804650
0.0365
-1.9614
0.0106
0.0117
9.0705e-001
1
0.0365
10023804651
-0.0491
-1.9546
0.0116
0.0110
8.8451e-001
1
-0.0491
10023804652
-0.0910
-0.6873
0.2285
0.1850
9.6647e-002
1
-0.0910
10023804653
0.0999
-1.7399
0.0165
0.0204
6.2537e-001
1
0.0999
10023804654
0.2831
-2.1151
0.0068
0.0107
5.8940e-001
1
0.2831
10023804655
0.0568
-0.1067
0.7339
0.8385
2.6075e-001
1
0.0568
10023804656
-0.0438
0.2080
1.6979
1.5355
3.7020e-001
1
-0.0438
10023804657
0.0014
-0.2767
0.5324
0.5354
9.7592e-001
1
0.0014
10023804658
0.0710
-1.6889
0.0194
0.0220
7.3066e-001
1
0.0710
10023804659
0.0275
0.4273
2.5923
2.7767
6.5159e-001
1
0.0275
10023804660
0.0413
-1.4840
0.0321
0.0346
7.8671e-001
1
0.0413
10023804661
0.0404
-1.2554
0.0529
0.0587
6.6172e-001
1
0.0404
10023804662
0.0089
1.0922
12.3049
12.5097
9.0712e-001
1
0.0089
10023804663
-0.0245
-1.2858
0.0536
0.0507
7.3454e-001
1
-0.0245
Total number of rows: 23570 Table truncated, full table size 1446 Kbytes .Supplementary data files not provided
Processed data included within Sample table