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Status
Public on Apr 02, 2022
Title
Study participant 100-057
Sample type
RNA
Source name
Primary p16(+) oropharyngeal squamous cell carcinoma
Organism
Homo sapiens
Characteristics
age(years): 54 sex (1=male,2=female): 1 race (1=white,2=asian): 1 tobacco (1=current,2=former,3=never): 3 subsite(1=tonsils and pillars,2=base of tongue,3=pharyngeal overlapping): 2 clin_t_stage(1=t0,2=t1,3=t2,4=t3,5=t4a,6=t4b): 4 clin_n_stage(1=n0,2=n1,3=n2,4=n3): 2 clin_m_stage(1=m0,2=m1): 1 clin_stage(1=stage i,2=stage ii,3=stage iii,4=stage iv): 2 recurrence(0=no recurrence,1=recurrence): 0 recurrence_time(days): 1391 vital_status(0=alive,1=dead): 0 os_time(days): 1391 disease state: human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) tissue: HPV(+) OPSCC tumor
Growth protocol
NA
Extracted molecule
total RNA
Extraction protocol
RNA was extracted from samples using QIAGEN RNeasy kits
Label
n/a
Label protocol
Hybridized transcripts were purified and immobilized on a sample cartridge
Hybridization protocol
Transcripts were hybridized to a panel of 770 probes (Nanostring IO360)
Scan protocol
Counts of hybridized transcripts were read using the nCounter platform
Data processing
Raw counts were normalized with the nSolver software (4.0) package using the geometric mean of both positive control probes and housekeeping probes. A background threshold count was set to 20.
Submission date
Mar 20, 2022
Last update date
Apr 02, 2022
Contact name
Jose P Zevallos
E-mail(s)
jpzevallos@wustl.edu
Organization name
Washington University School of Medicine
Department
Otolaryngology - Head and Neck Surgery
Street address
660 South Euclid Avenue, Campus Box 8115
City
St Louis
State/province
MO
ZIP/Postal code
63110
Country
USA
Platform ID
GPL32069
Series (1)
GSE199029
Integrative genome analysis reveals low T cell infiltration as the primary feature of tobacco use in HPV(+) oropharyngeal cancer
Data table header descriptions
ID_REF
VALUE
Normalized hybridization counts
Data table
ID_REF
VALUE
A2M
3023.27
ACVR1C
554.33
ADAM12
524.3
ADGRE1
20.29
ADM
1203.63
ADORA2A
227.25
AKT1
2500.59
ALDOA
15773.75
ALDOC
344.94
ANGPT1
155.02
ANGPT2
2317.16
ANGPTL4
2026.6
ANLN
1540.45
APC
1413.02
APH1B
99.02
API5
4877
APLNR
187.48
APOE
2628.82
APOL6
1861.03
AQP9
230.5
Total number of rows: 760 Table truncated, full table size 9 Kbytes .Supplementary data files not provided
Processed data included within Sample table