|
| Status |
Public on Jun 22, 2024 |
| Title |
A19-41_A10_Tumor |
| Sample type |
SRA |
| |
|
| Source name |
tumor
|
| Organism |
Homo sapiens |
| Characteristics |
tissue: tumor
age: 65
Sex: M
donor: SIC_136
group: irMyocarditis
|
| Extracted molecule |
other |
| Extraction protocol |
Bulk TCRseq data was generated on Formalin-fixed, paraffin-embedded slides. Genomic DNA was extracted using the AllPrep DNA/RNA FFPE Kit instructions (Qiagen)
T-cell receptor β chain (TCR-β) sequencing of the CDR3 region was performed (immunoSEQ ® human T-cell receptor beta [hsTCRB], Adaptive Biotechnologies)
|
| |
|
| Library strategy |
OTHER |
| Library source |
other |
| Library selection |
other |
| Instrument model |
Illumina NextSeq 500 |
| |
|
| Description |
Adaptive bulk TCRseq data
|
| Data processing |
Adaptive Biotechnologies processed and aligned the raw data with proprietary software
Assembly: GRCh38
Supplementary files format and content: tab-seperated value files that include all relevant info for recovered and constructed TCR sequences
Library strategy: TCR-seq
|
| |
|
| Submission date |
Jan 16, 2024 |
| Last update date |
Jun 22, 2024 |
| Contact name |
Neal Patrick Smith |
| E-mail(s) |
nsmith19@mgh.harvard.edu
|
| Organization name |
Massachusetts General Hospital
|
| Street address |
149 13th Street
|
| City |
Charlestown |
| State/province |
MA |
| ZIP/Postal code |
02129 |
| Country |
USA |
| |
|
| Platform ID |
GPL18573 |
| Series (1) |
| GSE228597 |
Immunologic drivers of immune checkpoint inhibitor therapy myocarditis, fatality and anti-tumor response in cancer patients |
|
