|
| Status |
Public on Nov 06, 2012 |
| Title |
high grade serous ovarian cancer_HGSC1 |
| Sample type |
genomic |
| |
|
| Source name |
high grade serous ovarian cancer
|
| Organism |
Homo sapiens |
| Characteristics |
tissue: ovarian cancer ascites
pathologic subtype: Serous
Stage: IIIC
grade: 3
grade h/l: H
primary site: Ovarian
tso (tumor sample origin): Ascites
age: 62
residual disease: < 1cm
resistance: 0
progressed: 1
pfstx (months): 16.4
floh%: 36.9
bpm: 1
|
| Extracted molecule |
genomic DNA |
| Extraction protocol |
DNA extracted by proteinase K disgestion-phenochloroform extraction or Qigen DNA extraction kit from ovarian cancer cells enriched from tumor tissues by needle-microdissection or from ascites by affinity enrichment with anti-EPCAM-conjugated beads.
|
| Label |
Biotin
|
| Label protocol |
Affymetrix standard protocol
|
| |
|
| Hybridization protocol |
Affymetrix standard protocol
|
| Scan protocol |
Affymetrix standard protocol
|
| Description |
PFSTx: progression free survival (months) from the end of primary platinum/taxol treatment
BPM: BRCA1 promoter methylation
Grade H/L: high grade (grade 2, 3) / low (grade 1) grade
|
| Data processing |
initially performed by DFCI microarray core using softwares from Affymetrix. The data for allelic signals in the sample data table were directly exported by dChip software (dChip_2010_1.exe) after the processing the data from cel files.
|
| |
|
| Submission date |
Jul 05, 2012 |
| Last update date |
Aug 19, 2016 |
| Contact name |
Zhigang C Wang |
| E-mail(s) |
zhigang_wang@dfci.harvard.edu
|
| Phone |
(617)582-7353
|
| Fax |
(617)6323097
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Cancer Biology
|
| Street address |
450 Brookline Ave SM936A
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platform ID |
GPL3718 |
| Series (1) |
| GSE39130 |
Profiles of genomic instability in high-grade serous ovarian cancer (HGSC) predict treatment outcome |
|
| Relations |
| Reanalyzed by |
GSE85838 |
