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    plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 [ Danio rerio (zebrafish) ]

    Gene ID: 541487, updated on 2-Nov-2024

    Summary

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    Official Symbol
    plcxd3provided by ZNC
    Official Full Name
    phosphatidylinositol-specific phospholipase C, X domain containing 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050327-10
    See related
    Ensembl:ENSDARG00000054794 AllianceGenome:ZFIN:ZDB-GENE-050327-10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc10h08; wu:fc10h08; wu:fq34d10; zgc:110845; wu:cegs2770
    Summary
    Predicted to enable phosphoric diester hydrolase activity. Predicted to act upstream of or within lipid catabolic process and signal transduction. Predicted to be active in synapse. Is expressed in basal plate midbrain region; central nervous system; neurons; otic vesicle; and pharyngeal arch. Orthologous to human PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See plcxd3 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (31821441..31862843)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (31812209..31853611)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene rab7a interacting mon1-ccz1 complex subunit 1 Neighboring gene 3-oxoacid CoA transferase 1a Neighboring gene complement component 7a Neighboring gene regulator of G protein signaling 7 binding protein a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of receptors for growth hormone and somatolactin in fish and land vertebrates: lessons from the lungfish and sturgeon orthologues. Fukamachi S, et al. J Mol Evol, 2007 Oct. PMID 17917757
    2. Identification of enhancer regulatory elements that direct epicardial gene expression during zebrafish heart regeneration. Cao Y, et al. Development, 2022 Feb 15. PMID 35179181, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoric diester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    PI-PLC X domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014300.1 → NP_001014322.1  PI-PLC X domain-containing protein 3

      See identical proteins and their annotated locations for NP_001014322.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091866
      UniProtKB/Swiss-Prot
      Q58EK3
      UniProtKB/TrEMBL
      A8KC50
      Related
      ENSDARP00000071521.4, ENSDART00000077053.5
      Conserved Domains (1) summary
      cd08616
      Location:19 → 311
      PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      31821441..31862843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58EK3.1 GenPept UniProtKB/Swiss-Prot:Q58EK3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.