mpst mercaptopyruvate sulfurtransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mpstprovided by ZNC
Official Full Name: mercaptopyruvate sulfurtransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9020
See related: Ensembl:ENSDARG00000093235 AllianceGenome:ZFIN:ZDB-GENE-030131-9020
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: 3-mst; fa96h11; wu:fa96h11; zgc:162544
Summary: Enables 3-mercaptopyruvate sulfurtransferase activity. Predicted to be involved in transsulfuration. Predicted to be active in mitochondrion. Is expressed in central nervous system and heart. Orthologous to human MPST (mercaptopyruvate sulfurtransferase) and TST (thiosulfate sulfurtransferase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (25166805..25169823)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (25036257..25039275)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Generation and Characterization of a CRISPR/Cas9 -Induced 3-mst Deficient Zebrafish.
Title: Generation and Characterization of a CRISPR/Cas9 -Induced 3-mst Deficient Zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 3-mercaptopyruvate sulfurtransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3-mercaptopyruvate sulfurtransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables sulfurtransferase activity	IEA Inferred from Electronic Annotation more info
enables thiosulfate sulfurtransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables thiosulfate sulfurtransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 3-mercaptopyruvate sulfurtransferase

NP_001082815.1

EC 2.8.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089346.1 → NP_001082815.1 3-mercaptopyruvate sulfurtransferase

See identical proteins and their annotated locations for NP_001082815.1

Status: PROVISIONAL

Source sequence(s)

BC139598

UniProtKB/TrEMBL

A4QP04

Related

ENSDARP00000071960.4, ENSDART00000077493.5

Conserved Domains (3) summary

PLN02723
Location:3 → 286

PLN02723; 3-mercaptopyruvate sulfurtransferase

cd01448
Location:8 → 137

TST_Repeat_1; Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it ...

cd01449
Location:162 → 278

TST_Repeat_2; Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue.