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    GLD1 Gld1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856225, updated on 17-May-2024

    Summary

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    Gene symbol
    GLD1
    Gene description
    Gld1p
    Primary source
    FungiDB:YPR109W
    Locus tag
    YPR109W
    See related
    SGD:S000006313; AllianceGenome:SGD:S000006313; VEuPathDB:YPR109W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in protein-containing complex localization. Located in endoplasmic reticulum. Part of Dsc E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See GLD1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (744689..745573)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene proteasome regulatory particle lid subunit RPN7 Neighboring gene tRNA-Thr Neighboring gene DNA-directed RNA polymerase core subunit RPC40 Neighboring gene serine/threonine-protein kinase DBF20

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characteristics affecting expression and solubilization of yeast membrane proteins. White MA, et al. J Mol Biol, 2007 Jan 19. PMID 17078969, Free PMC Article
    2. The budding index of Saccharomyces cerevisiae deletion strains identifies genes important for cell cycle progression. Zettel MF, et al. FEMS Microbiol Lett, 2003 Jun 27. PMID 12829295
    3. Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system. Yang X, et al. Elife, 2018 Jan 22. PMID 29355480, Free PMC Article
    4. Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism. Schmidt O, et al. EMBO J, 2019 Aug 1. PMID 31368600, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. Bussey H, et al. Nature, 1997 May 29. PMID 9169875

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in localization within membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein-containing complex localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Gld1p
    NP_015434.1
    • Component of Dsc E3 ligase complex in Golgi and endosomes; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; diploid deletion strain has high budding index

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      744689..745573
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184206.1 → NP_015434.1  TPA: Gld1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015434.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W4A8, Q06104, Q6B2S3
      UniProtKB/TrEMBL
      A0A8H4BW92, B3LK73, G2WPS6, N1P2A7
      Conserved Domains (1) summary
      pfam08508
      Location:34 → 230
      DUF1746; Fungal domain of unknown function (DUF1746)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06104.1

    Gene LinkOut

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