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    klhl18 kelch-like family member 18 [ Danio rerio (zebrafish) ]

    Gene ID: 327574, updated on 27-Mar-2024

    Summary

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    Official Symbol
    klhl18provided by ZNC
    Official Full Name
    kelch-like family member 18provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5785
    See related
    Ensembl:ENSDARG00000004306 AllianceGenome:ZFIN:ZDB-GENE-030131-5785
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55359; wu:fi18c08
    Summary
    Orthologous to human KLHL18 (kelch like family member 18). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See klhl18 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (32743807..32756448)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (32760589..32773230)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene poly-U binding splicing factor a Neighboring gene nuclear receptor binding protein 2a Neighboring gene uncharacterized LOC101887149 Neighboring gene beaded filament structural protein 2, phakinin Neighboring gene zgc:136930

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin. Feiner N, et al. Genome Biol Evol, 2013. PMID 23843192, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    kelch-like protein 18
    Names
    kelch-like 18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199830.1 → NP_956124.1  kelch-like protein 18

      See identical proteins and their annotated locations for NP_956124.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045319
      UniProtKB/TrEMBL
      Q7ZW26
      Related
      ENSDARP00000025821.8, ENSDART00000022909.9
      Conserved Domains (6) summary
      smart00612
      Location:339 → 385
      Kelch; Kelch domain
      PHA03098
      Location:36 → 507
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:328 → 371
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:30 → 134
      BTB; BTB/POZ domain
      pfam01344
      Location:515 → 559
      Kelch_1; Kelch motif
      pfam07707
      Location:142 → 244
      BACK; BTB And C-terminal Kelch

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      32743807..32756448
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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