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    SMTN smoothelin [ Homo sapiens (human) ]

    Gene ID: 6525, updated on 14-Nov-2024

    Summary

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    Official Symbol
    SMTNprovided by HGNC
    Official Full Name
    smoothelinprovided by HGNC
    Primary source
    HGNC:HGNC:11126
    See related
    Ensembl:ENSG00000183963 MIM:602127; AllianceGenome:HGNC:11126
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2011]
    Expression
    Broad expression in prostate (RPKM 39.0), endometrium (RPKM 30.0) and 20 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See SMTN in Genome Data Viewer
    Location:
    22q12.2
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (31064118..31104624)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (31527653..31568123)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (31460104..31500610)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18847 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13620 Neighboring gene taurine up-regulated 1 Neighboring gene MPRA-validated peak4481 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:31439932-31440502 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:31440503-31441072 Neighboring gene RNA, 7SL, cytoplasmic 633, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13621 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13622 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13623 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:31481712-31482338 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:31492256-31492830 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:31492831-31493404 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:31499788-31500738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:31502238-31503010 Neighboring gene uncharacterized LOC105372995 Neighboring gene uncharacterized LOC124905100 Neighboring gene selenoprotein M

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. A haplotype of the SMTN gene associated with myocardial infarction in Japanese women. Jiang J, et al. Genet Test Mol Biomarkers, 2012 Sep. PMID 22963604
    2. Expression of the smoothelin gene is mediated by alternative promoters. Rensen SS, et al. Cardiovasc Res, 2002 Sep. PMID 12176134
    3. Smoothelin and WT-1 expression in glomus tumors and glomuvenous malformations. Aneiros-Fernandez J, et al. Histol Histopathol, 2017 Feb. PMID 27184662
    4. Identification and characterization of novel smoothelin isoforms in vascular smooth muscle. Krämer J, et al. J Vasc Res, 2001 Mar-Apr. PMID 11316948
    5. Apparent up-regulation of stimulatory G-protein alpha subunits in the pregnant human myometrium is mimicked by elevated smoothelin expression. Gsell S, et al. FASEB J, 2000 Jan. PMID 10627276

    See all (69) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Analysis of Tumor Depth Invasion With Anti-Smoothelin Antibody in Equivocal Transurethral Resection of Urinary Bladder Tumor Surgical Specimens.
      Title: Analysis of Tumor Depth Invasion With Anti-Smoothelin Antibody in Equivocal Transurethral Resection of Urinary Bladder Tumor Surgical Specimens.
    2. Smoothelin is a specific marker for smooth muscle cells with contractile capacity which has not been widely studied in glomus lesions. in this study, glomic cells showed cytoplasmic positivity for smoothelin. Smoothelin expression in glomic cells indicates that they are contractile smooth muscle cells, and thus its role in routine diagnosis should be considered.
      Title: Smoothelin and WT-1 expression in glomus tumors and glomuvenous malformations.
    3. Caldesmon and smoothelin staining allows better delineation of the muscularis propria from the desmoplastic stromal reaction which provides a critical aide for proper staging of colonic adenocarcinomas.
      Title: Smoothelin and caldesmon are reliable markers for distinguishing muscularis propria from desmoplasia: a critical distinction for accurate staging colorectal adenocarcinoma.
    4. During development of advanced liver fibrosis, a subpopulation of myofibroblasts expressing smoothelin may be derived from vascular smooth muscle cells.
      Title: Smoothelin, a new marker to determine the origin of liver fibrogenic cells.
    5. lower level of expresseion in colonic inertia patients
      Title: Smoothelin expression in the gastrointestinal tract: implication in colonic inertia.
    6. The objective of the following study was to record the specificity and sensitivity of alpha5(IV) loss, smoothelin expression and PLAP expression as markers of gastrointestinal smooth muscle neoplasms
      Title: A study of α5 chain of collagen IV, caldesmon, placental alkaline phosphatase and smoothelin as immunohistochemical markers of gastrointestinal smooth muscle neoplasms.
    7. There is an association between essential hypertension and the SMTN gene.
      Title: Haplotype of smoothelin gene associated with essential hypertension.
    8. Phenotypic expression of alpha-smooth muscle actin, smooth muscle myosin heavy chain 2, and smoothelin were significantly decreased in the dissected media, whereas that of osteopontin was elevated.
      Title: Association of smooth muscle cell phenotypes with extracellular matrix disorders in thoracic aortic dissection.
    9. Smoothelin haplotype constructed using rs5997872, rs56095120, rs9621187 and rs10304 was a useful genetic marker of cerebral infarction in Japanese men.
      Title: Association of the smoothelin (SMTN) gene with cerebral infarction in men: a haplotype-based case-control study.
    10. for the Japanese women, the frequency of the C-T-T-G haplotype (established by rs5997872, rs56095120, rs9621187, and rs10304) was significantly higher in the myocardial infarction group than in the control group
      Title: A haplotype of the SMTN gene associated with myocardial infarction in Japanese women.
    Submit: New GeneRIF Correction See all GeneRIFs (18)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genetic variants associated with disordered eating.
    EBI GWAS Catalog

    Variation

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    See Variation Viewer (GRCh37.p13)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ35168, FLJ35365, FLJ35620, FLJ38597

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables actin binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of muscle TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in muscle organ development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in smooth muscle contraction TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    smoothelin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029838.2 RefSeqGene

      Range
      22202..45508
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001207017.1 → NP_001193946.1  smoothelin isoform d

      See identical proteins and their annotated locations for NP_001193946.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) encodes the longest isoform (d).
      Source sequence(s)
      AK304084, BC034237, Z49989
      Consensus CDS
      CCDS74845.1
      UniProtKB/TrEMBL
      A0A087X1R1, B4E229
      Related
      ENSP00000484398.1, ENST00000619644.5
      Conserved Domains (2) summary
      cd00014
      Location:887 → 991
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:655 → 704
      Smoothelin; Smoothelin cytoskeleton protein

    2. NM_001207018.2 → NP_001193947.1  smoothelin isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks two exons from the 5' end, has an alternate 5' exon, lacks an in-frame exon in the middle region and has an additional exon in the 3' region, compared to variant 4. The resulting isoform (e) has distinct N- and C-termini, and lacks an internal segment, compared to isoform d.
      Source sequence(s)
      AK295418, BC034237, Z49989
      Consensus CDS
      CCDS74846.1
      UniProtKB/TrEMBL
      A0A087WVP4, B4DI56
      Related
      ENSP00000479578.1, ENST00000612341.4
      Conserved Domains (2) summary
      cd00014
      Location:858 → 958
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:626 → 675
      Smoothelin; Smoothelin cytoskeleton protein

    3. NM_001382638.1 → NP_001369567.1  smoothelin isoform b

      Status: REVIEWED

      Source sequence(s)
      AC005005
      Consensus CDS
      CCDS13888.1
      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:800 → 911
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    4. NM_001382639.1 → NP_001369568.1  smoothelin isoform b

      Status: REVIEWED

      Source sequence(s)
      AC005005
      Consensus CDS
      CCDS13888.1
      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:800 → 911
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    5. NM_001382640.1 → NP_001369569.1  smoothelin isoform b

      Status: REVIEWED

      Source sequence(s)
      AC005005
      Consensus CDS
      CCDS13888.1
      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:800 → 911
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    6. NM_001382641.1 → NP_001369570.1  smoothelin isoform b

      Status: REVIEWED

      Source sequence(s)
      AC005005
      Consensus CDS
      CCDS13888.1
      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:800 → 911
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    7. NM_001382642.1 → NP_001369571.1  smoothelin isoform f

      Status: REVIEWED

      Source sequence(s)
      AC005005
      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      pfam12510
      Location:664 → 713
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:894 → 1005
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    8. NM_001382643.1 → NP_001369572.1  smoothelin isoform g

      Status: REVIEWED

      Source sequence(s)
      AC005005
      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      pfam12510
      Location:624 → 673
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:854 → 965
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    9. NM_001382644.1 → NP_001369573.1  smoothelin isoform g

      Status: REVIEWED

      Source sequence(s)
      AC005005
      UniProtKB/TrEMBL
      C9JYU8
      Related
      ENSP00000401341.2, ENST00000440425.6
      Conserved Domains (2) summary
      pfam12510
      Location:624 → 673
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:854 → 965
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    10. NM_001382645.1 → NP_001369574.1  smoothelin isoform h

      Status: REVIEWED

      Source sequence(s)
      AC005005
      UniProtKB/TrEMBL
      B3KY41

    11. NM_001382646.1 → NP_001369575.1  smoothelin isoform i

      Status: REVIEWED

      Source sequence(s)
      AC005005
      UniProtKB/TrEMBL
      B4E229
      Conserved Domains (1) summary
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein

    12. NM_001382647.1 → NP_001369576.1  smoothelin isoform j

      Status: REVIEWED

      Source sequence(s)
      AC005005
      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:724 → 835
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    13. NM_001382648.1 → NP_001369577.1  smoothelin isoform k

      Status: REVIEWED

      Source sequence(s)
      AC005005
      Conserved Domains (2) summary
      pfam12510
      Location:228 → 277
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:458 → 569
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    14. NM_006932.5 → NP_008863.3  smoothelin isoform c

      See identical proteins and their annotated locations for NP_008863.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has an alternate 5' exon, which results in a downstream AUG start codon, and lacks an in-frame exon in the middle region, compared to variant 4. The resulting isoform (c, also referred to as L1, B and c1) is shorter at the N-terminus and lacks an internal segment, compared to isoform d. This isoform is highly expressed in all vascularized organs and represents a vascular smooth muscle-specific form. This transcript also includes an alternate downstream translation initiation site, which results in the smoothelin-A product, a visceral smooth muscle-specific form.
      Source sequence(s)
      AJ010306, BC034237, DC342566, Z49989
      Consensus CDS
      CCDS13886.1
      UniProtKB/Swiss-Prot
      O00569, O95769, O95937, P53814, Q8N4H8, Q8WWW1, Q8WWW2, Q9P1S8, Q9UIT1, Q9UIT2
      UniProtKB/TrEMBL
      C9JYU8
      Related
      ENSP00000328635.5, ENST00000347557.6
      Conserved Domains (2) summary
      cd00014
      Location:802 → 906
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein

    15. NM_134269.3 → NP_599031.1  smoothelin isoform b

      See identical proteins and their annotated locations for NP_599031.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) has an alternate 5' exon, which results in a downstream AUG start codon, lacks an in-frame exon in the middle region and has an additional exon in the 3' region, compared to variant 4. The resulting isoform (b, also referred to as L2 and B2) is shorter at the N-terminus, lacks a segment in the middle region and has a slightly shorter and distinct C-terminus, compared to isoform d.
      Source sequence(s)
      BC034237, DC342566, Z49989
      Consensus CDS
      CCDS13888.1
      UniProtKB/TrEMBL
      C9JYU8
      Related
      ENSP00000329532.7, ENST00000333137.12
      Conserved Domains (2) summary
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein
      cd21259
      Location:800 → 911
      CH_SMTNB; calponin homology (CH) domain found in smoothelin-B and similar proteins

    16. NM_134270.3 → NP_599032.2  smoothelin isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) has an alternate 5' exon, which results in a downstream AUG start codon, lacks an in-frame exon in the middle region and has an additional in-frame exon in the 3' region, compared to variant 4. The resulting isoform (a, also referred to as B3) is shorter at the N-terminus, lacks a segment in the middle region and has an additional segment in the C-terminal region, compared to isoform d.
      Source sequence(s)
      BC034237, DC342566, Z49989
      Consensus CDS
      CCDS13887.1
      UniProtKB/TrEMBL
      C9JYU8
      Related
      ENSP00000351593.1, ENST00000358743.5
      Conserved Domains (2) summary
      cd00014
      Location:802 → 929
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:570 → 619
      Smoothelin; Smoothelin cytoskeleton protein

    RNA

    1. NR_168472.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005005

    2. NR_168473.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005005

    3. NR_168474.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005005

    4. NR_168475.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005005
      Related
      ENST00000489337.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      31064118..31104624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017028913.2 → XP_016884402.1  smoothelin isoform X1

      UniProtKB/TrEMBL
      A0A087X1R1, B4E229
      Conserved Domains (2) summary
      cd00014
      Location:887 → 991
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:655 → 704
      Smoothelin; Smoothelin cytoskeleton protein

    2. XM_017028917.2 → XP_016884406.1  smoothelin isoform X5

      UniProtKB/TrEMBL
      B4E229

    3. XM_011530336.3 → XP_011528638.1  smoothelin isoform X6

      UniProtKB/TrEMBL
      B4E229
      Conserved Domains (2) summary
      cd00014
      Location:811 → 915
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:655 → 704
      Smoothelin; Smoothelin cytoskeleton protein

    4. XM_017028914.2 → XP_016884403.1  smoothelin isoform X3

      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      cd00014
      Location:856 → 960
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:624 → 673
      Smoothelin; Smoothelin cytoskeleton protein

    5. XM_011530338.3 → XP_011528640.1  smoothelin isoform X10

      UniProtKB/TrEMBL
      C9JYU8
      Conserved Domains (2) summary
      cd00014
      Location:780 → 884
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      pfam12510
      Location:624 → 673
      Smoothelin; Smoothelin cytoskeleton protein

    6. XM_047441466.1 → XP_047297422.1  smoothelin isoform X2

    7. XM_047441467.1 → XP_047297423.1  smoothelin isoform X4

    8. XM_047441469.1 → XP_047297425.1  smoothelin isoform X8

    9. XM_047441468.1 → XP_047297424.1  smoothelin isoform X7

    10. XM_047441470.1 → XP_047297426.1  smoothelin isoform X11

    11. XM_017028918.2 → XP_016884407.1  smoothelin isoform X9

      UniProtKB/TrEMBL
      B3KUD6

    12. XM_047441471.1 → XP_047297427.1  smoothelin isoform X13

    13. XM_011530339.3 → XP_011528641.1  smoothelin isoform X12

      Conserved Domains (1) summary
      pfam12510
      Location:655 → 704
      Smoothelin; Smoothelin cytoskeleton protein

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      31527653..31568123
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054325853.1 → XP_054181828.1  smoothelin isoform X1

    2. XM_054325857.1 → XP_054181832.1  smoothelin isoform X5

    3. XM_054325858.1 → XP_054181833.1  smoothelin isoform X6

    4. XM_054325855.1 → XP_054181830.1  smoothelin isoform X3

    5. XM_054325862.1 → XP_054181837.1  smoothelin isoform X10

    6. XM_054325854.1 → XP_054181829.1  smoothelin isoform X2

    7. XM_054325856.1 → XP_054181831.1  smoothelin isoform X4

    8. XM_054325860.1 → XP_054181835.1  smoothelin isoform X8

    9. XM_054325859.1 → XP_054181834.1  smoothelin isoform X7

    10. XM_054325863.1 → XP_054181838.1  smoothelin isoform X11

    11. XM_054325861.1 → XP_054181836.1  smoothelin isoform X9

    12. XM_054325866.1 → XP_054181841.1  smoothelin isoform X13

    13. XM_054325865.1 → XP_054181840.1  smoothelin isoform X12

    14. XM_054325864.1 → XP_054181839.1  smoothelin isoform X14

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53814.7 GenPept UniProtKB/Swiss-Prot:P53814

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Molecular Biology Databases
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