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    TTC34 tetratricopeptide repeat domain 34 [ Homo sapiens (human) ]

    Gene ID: 100287898, updated on 17-Sep-2024

    Summary

    Official Symbol
    TTC34provided by HGNC
    Official Full Name
    tetratricopeptide repeat domain 34provided by HGNC
    Primary source
    HGNC:HGNC:34297
    See related
    Ensembl:ENSG00000215912 AllianceGenome:HGNC:34297
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 2.4), thyroid (RPKM 0.8) and 14 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See TTC34 in Genome Data Viewer
    Location:
    1p36.32
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (2636986..2801693, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (2078230..2301463, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (2568425..2718258, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:2519024-2519656 Neighboring gene peroxiredoxin like 2B Neighboring gene ReSE screen-validated silencer GRCh37_chr1:2556762-2557011 Neighboring gene Sharpr-MPRA regulatory region 11692 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:2562185-2562685 Neighboring gene membrane metalloendopeptidase like 1 Neighboring gene MPRA-validated peak16 silencer Neighboring gene MMEL1 antisense RNA 1 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2586483-2586987 Neighboring gene Sharpr-MPRA regulatory region 15700 Neighboring gene OCT4 hESC enhancer GRCh37_chr1:2587878-2588769 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2588891-2589402 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2589915-2590426 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2597430-2597930 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2597931-2598431 Neighboring gene OCT4 hESC enhancer GRCh37_chr1:2600600-2601101 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2601784-2602520 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2603256-2603991 Neighboring gene OCT4 hESC enhancer GRCh37_chr1:2607057-2607636 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:2607637-2608216 Neighboring gene OCT4 hESC enhancer GRCh37_chr1:2609432-2609933 Neighboring gene OCT4 hESC enhancer GRCh37_chr1:2610686-2611577 Neighboring gene OCT4 hESC enhancer GRCh37_chr1:2613783-2614607 Neighboring gene OCT4 hESC enhancer GRCh37_chr1:2628928-2629429 Neighboring gene uncharacterized LOC105378602 Neighboring gene uncharacterized LOC105378601 Neighboring gene uncharacterized LOC112268220 Neighboring gene uncharacterized LOC107985732 Neighboring gene uncharacterized LOC105378600 Neighboring gene uncharacterized LOC105378598 Neighboring gene uncharacterized LOC107984904 Neighboring gene uncharacterized LOC105378599 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:2706849-2707508 Neighboring gene uncharacterized LOC124903825 Neighboring gene uncharacterized LOC124903826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:2766741-2767242 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:2824551-2825750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:2837727-2838286 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 57 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_6521 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:2931349-2932112 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_6546 Neighboring gene actin related protein T2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    tetratricopeptide repeat protein 34
    Names
    TPR repeat protein 34
    TPR repeat-containing protein ENSP00000383873

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001242672.3NP_001229601.2  tetratricopeptide repeat protein 34

      Status: VALIDATED

      Source sequence(s)
      AC242022, AL592464, AL831784
      Consensus CDS
      CCDS55565.2
      UniProtKB/TrEMBL
      A0A1C7CYW7
      Related
      ENSP00000383873.4, ENST00000401095.9
      Conserved Domains (2) summary
      sd00006
      Location:689720
      TPR; TPR repeat [structural motif]
      cl26002
      Location:557925
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      2636986..2801693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_187515.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      187771..353522 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      2078230..2301463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)