Congenital prothrombin deficiency
- Synonyms
- Congenital factor II deficiency; Factor II deficiency; HYPOPROTHROMBINEMIA; Hereditary factor II deficiency disease; Inherited hypoprothrombinemia; Inherited prothrombin deficiency
- Modes of inheritance
- Autosomal recessive inheritance (Orphanet)
Summary
Available tests
Check Related conditions for additional relevant tests.
Genes See tests for all associated and related genes
Also known as: PT, RPRGL2, THPH1, F2
Summary: coagulation factor II, thrombin
Clinical features
Help- Abnormality of blood and blood-forming tissues
- Epistaxis
Epistaxis
- MedGen UID: 4996
- Concept ID: C0014591
- Finding: Pathologic Function
Abnormality of blood and blood-forming tissues
- Gingival bleeding
Gingival bleeding
- MedGen UID: 42218
- Concept ID: C0017565
- Finding: Pathologic Function
Abnormality of blood and blood-forming tissues
- Menorrhagia
Menorrhagia
- MedGen UID: 44358
- Concept ID: C0025323
- Finding: Pathologic Function
Abnormality of blood and blood-forming tissues
- Prolonged bleeding time
Prolonged bleeding time
- MedGen UID: 56231
- Concept ID: C0151529
- Finding: Finding
Abnormality of blood and blood-forming tissues
- Prolonged partial thromboplastin time
Prolonged partial thromboplastin time
- MedGen UID: 66815
- Concept ID: C0240671
- Finding: Finding
Abnormality of blood and blood-forming tissues
- Prolonged prothrombin time
Prolonged prothrombin time
- MedGen UID: 208879
- Concept ID: C0853225
- Finding: Finding
Abnormality of blood and blood-forming tissues
- Epistaxis
- Abnormality of the cardiovascular system
- Joint hemorrhage
Joint hemorrhage
- MedGen UID: 5479
- Concept ID: C0018924
- Finding: Pathologic Function
Abnormality of the cardiovascular system
- Joint hemorrhage
- Abnormality of the digestive system
- Gastrointestinal hemorrhage
Gastrointestinal hemorrhage
- MedGen UID: 8971
- Concept ID: C0017181
- Finding: Pathologic Function
Abnormality of the digestive system
- Gastrointestinal hemorrhage
- Abnormality of the integument
- Bruising susceptibility
Bruising susceptibility
- MedGen UID: 140849
- Concept ID: C0423798
- Finding: Finding
Abnormality of the integument
- Ecchymosis
Ecchymosis
- MedGen UID: 8524
- Concept ID: C0013491
- Finding: Finding
Abnormality of the integument
- Bruising susceptibility
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