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GTR Home > Conditions/Phenotypes > Spermatogenic failure 10

Spermatogenic failure 10

Synonyms
SPERMATOGENIC FAILURE 10, SUSCEPTIBILITY TO; SPERMATOGENIC FAILURE WITH DEFECTIVE SPERM ANNULUS

Summary

Spermatogenic failure-10 (SPGF10) is associated with a defective annulus, a ring structure that demarcates the midpiece and the principal piece of the sperm tail. The firm attachment of the annulus to the flagellar membrane suggests that it may supply mechanical support and prevent displacement of the caudal mitochondrial helix (summary by Kuo et al., 2012). For a discussion of phenotypic and genetic heterogeneity of spermatogenic failure, see SPGF1 (258150). [from OMIM]

Available tests

5 tests are in the database for this condition.

Clinical tests (5 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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