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GTR Home > Conditions/Phenotypes > Atrial fibrillation, familial, 18

Summary

Familial atrial fibrillation is an inherited abnormality of the heart's normal rhythm. Atrial fibrillation is characterized by episodes of uncoordinated electrical activity (fibrillation) in the heart's upper chambers (the atria), which cause a fast and irregular heartbeat. If untreated, this abnormal heart rhythm (arrhythmia) can lead to dizziness, chest pain, a sensation of fluttering or pounding in the chest (palpitations), shortness of breath, or fainting (syncope). Atrial fibrillation also increases the risk of stroke and sudden death. Complications of atrial fibrillation can occur at any age, although some people with this heart condition never experience any health problems associated with the disorder. [from MedlinePlus Genetics]

Genes See tests for all associated and related genes

  • Also known as: ALC1, AMLC, GT1, PRO1957, MYL4
    Summary: myosin light chain 4

Clinical features

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