C26:0 Lyso-phosphatidylcholine
- GTR Test IDHelpEach Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version number is assigned.: GTR000500811.3
- Last updated: 2023-06-22
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- Test version history
Clinical testHelpIn the U.S., clinical tests must be performed under CLIA certification. When a lab uses the same methods for a test in both clinical and research settings, the test appears as two separate GTR records. for Acyl-CoA oxidase deficiency
Offered by Genetics Laboratory, Peroxisomal Disorders Section
Overview
Test name
HelpThe name the laboratory assigns the test. Used as the default title of the page specific to the test.C26:0 Lyso-phosphatidylcholine (26:0 LPC)
This is a clinical test intended for HelpPurposes or indications for the test. Lab-provided.: Diagnosis, Screening
Click Indication tab for more information.
submit selected test on requisition form that may be printed from our website
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: http://www.genetics.kennedykrieger.org/
Specimen source
Methodology
HelpThe assay's major method category (biochemical, cytogenetic or molecular genetics); method category (i.e. enzyme assay, chromosome breakage studies, targeted mutation analysis); methodology (i.e. the name of the method used) and instruments used when performing this test.- Biochemical Genetics
- AAnalyte
- Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
- AB Sciex API3000 tandem mass spectrometer with Schimadzu FPLC
- None/not applicable
Establish or confirm diagnosis
- Newborn screening for X-linked adrenoleukodystrophy (X-ALD): validation of a combined liquid chromatography-tandem mass spectrometric (LC-MS/MS) method. - PubMed ID: 19423374
Clinical validity
HelpHow consistently and accurately the test detects or predicts the intermediate or final outcomes of interest. Lab-provided.Positive range was determined by analysis of samples from males with adrenoleukodystrophy. Negative range was determined by analysis of 128 samples from individuals with normal plasma very ong chain fatty acids.
- Newborn screening for X-linked adrenoleukodystrophy (X-ALD): validation of a combined liquid chromatography-tandem mass spectrometric (LC-MS/MS) method. - PubMed ID: 19423374
Testing strategy
HelpThe lab's suggested sequence of ordering tests based on clinical scenarios. It may include information on: reflex testing including each test component, and scenarios which prompt additional components of testing; whether lab communicates interim results or automatically proceeds to further analyses; and if any components are performed in another laboratory.Screening 000 submit selected test on requisition form that may be printed from our website
Test services
HelpLaboratory's order or catalog code for the test (used in the order requisition form).- Clinical Testing/Confirmation of Mutations Identified Previously
- newborn screening
IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.