GTR Test Accession:
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GTR000527980.1
Last updated in GTR: 2015-09-01
View version history
GTR000527980.1, last updated: 2015-09-01
Last annual review date for the lab: 2024-07-23
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At a Glance
Test purpose:
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Drug Response;
Mutation Confirmation;
Pre-symptomatic; ...
Conditions (16):
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Genes (52):
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Methods (4):
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Molecular Genetics - Deletion/duplication analysis: Next-Generation (NGS)/Massively parallel sequencing (MPS); ...
Target population: Help
Cancer patients with diverse solid tumors and hematological malignancies
Clinical validity:
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Not provided
Clinical utility:
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Not provided
Ordering Information
Offered by:
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Test short name:
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Com.Pl.i.t. DX 54 genes
Specimen Source:
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- Cytological material
- Paraffin block
Who can order: Help
- Genetic Counselor
- Health Care Provider
- Licensed Physician
- Physician Assistant
- Public Health Mandate
Lab contact:
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Vasiliki Metaxa-Mariatou, MSc, Molecular Biologist & QA Manager
bmetaxa@genekor.com
+30 210 6032138
Eirini Papadopoulou, PhD, Group Leader of Oncogenetics
eirinipapad@genekor.com
+30 210 6032138
bmetaxa@genekor.com
+30 210 6032138
Eirini Papadopoulou, PhD, Group Leader of Oncogenetics
eirinipapad@genekor.com
+30 210 6032138
Contact Policy:
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Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order:
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Test service:
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Clinical Testing/Confirmation of Mutations Identified Previously
Informed consent required:
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No
Pre-test genetic counseling required:
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No
Post-test genetic counseling required:
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No
Recommended fields not provided:
Test Order Code,
Test strategy,
Test development
Conditions
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Total conditions: 16
Condition/Phenotype | Identifier |
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Test Targets
Genes
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Total genes: 52
Gene | Associated Condition | Germline or Somatic | Allele (Lab-provided) | Variant in NCBI |
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Methodology
Total methods: 4
Method Category
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Test method
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Instrument
Deletion/duplication analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
The Ion Proton™ System
Mutation scanning of select exons
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Sequence analysis of select exons
Next-Generation (NGS)/Massively parallel sequencing (MPS)
The Ion Proton™ System
Targeted variant analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
The Ion Proton™ System
Clinical Information
Test purpose:
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Drug Response;
Mutation Confirmation;
Pre-symptomatic;
Predictive;
Prognostic;
Risk Assessment;
Therapeutic management
Target population:
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Cancer patients with diverse solid tumors and hematological malignancies
Variant Interpretation:
Are family members with defined clinical status recruited to assess significance of VUS without charge?
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No.
No.
Will the lab re-contact the ordering physician if variant interpretation changes?
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Yes.
Yes.
Recommended fields not provided:
Clinical validity,
Clinical utility,
What is the protocol for interpreting a variation as a VUS?,
Is research allowed on the sample after clinical testing is complete?,
Sample negative report,
Sample positive report
Technical Information
Availability:
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Tests performed
Entire test performed in-house
Entire test performed in-house
Analytical Validity:
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yes 100%
Proficiency testing (PT):
Is proficiency testing performed for this test?
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Yes
Method used for proficiency testing: Help
Alternative Assessment
PT Provider: Help
European Molecular Genetics Quality Network, EMQN
Description of PT method: Help
and - UK NEQAS Molecular Genetics, Colorectal Cancer & Lung Cancer schemes - College of American Pathologists (CAP), MTP (Multigene Tumor Panel) & KIT/PDGFRA schemes
Yes
Method used for proficiency testing: Help
Alternative Assessment
PT Provider: Help
European Molecular Genetics Quality Network, EMQN
Description of PT method: Help
and - UK NEQAS Molecular Genetics, Colorectal Cancer & Lung Cancer schemes - College of American Pathologists (CAP), MTP (Multigene Tumor Panel) & KIT/PDGFRA schemes
Recommended fields not provided:
Test Confirmation,
Assay limitations,
Description of internal test validation method,
Citations for Analytical validity,
Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review:
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Not provided
Additional Information
Reviews:
Clinical resources:
Consumer resources:
IMPORTANT NOTE:
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Patients and consumers
with specific questions about a genetic test should contact a health care provider or a genetics professional.