Hereditary Gastric Cancer (CDH1)
Clinical Genetic Test
Help
offered by
GTR Test Accession: Help GTR000528058.1
CANCERBREAST DISORDERSCONNECTIVE TISSUE ... View more
Registered in GTR: 2015-09-03
Last annual review date for the lab: 2024-07-23 LinkOut
At a Glance
Mutation Confirmation; Pre-symptomatic; Prognostic; ...
Hereditary diffuse gastric adenocarcinoma; Breast adenocarcinoma; Breast lobular carcinoma
Genes (1): Help
CDH1 (16q22.1)
Molecular Genetics - Sequence analysis of the entire coding region: Bi-directional Sanger Sequencing; Next-Generation (NGS)/Massively parallel sequencing (MPS)
Hereditary Gastric Cancer
Not provided
Guidance for management
Ordering Information
Offered by: Help
Specimen Source: Help
  • Peripheral (whole) blood
Who can order: Help
  • Health Care Provider
  • Licensed Physician
  • Physician Assistant
  • Public Health Mandate
Lab contact: Help
Konstantinos Agiannitopoulos, MSc, Molecular Biologist
kagiannitopoulos@genekor.com
+30 210 6032138
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Test service: Help
Clinical Testing/Confirmation of Mutations Identified Previously
Informed consent required: Help
No
Pre-test genetic counseling required: Help
No
Post-test genetic counseling required: Help
No
Recommended fields not provided:
Conditions Help
Total conditions: 3
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 1
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 2
Method Category Help
Test method Help
Instrument
Sequence analysis of the entire coding region
Bi-directional Sanger Sequencing
Sequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Applied Biosystems 3130 Genetic Analyzer
Clinical Information
Test purpose: Help
Mutation Confirmation; Pre-symptomatic; Prognostic; Risk Assessment; Screening; Therapeutic management
Target population: Help
Hereditary Gastric Cancer
Variant Interpretation:
Are family members with defined clinical status recruited to assess significance of VUS without charge? Help
No.

Will the lab re-contact the ordering physician if variant interpretation changes? Help
Yes.
Recommended fields not provided:
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
yes 100%
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
No
Recommended fields not provided:
Regulatory Approval
FDA Review: Help
Not provided
Additional Information

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