PAI1 4G
GTR Test Accession: Help GTR000552064.1
INHERITED DISEASEINHERITED DISEASE SUSCEPTIBILITYCARDIOVASCULAR ... View more
Last updated in GTR: 2016-09-20
Last annual review date for the lab: 2023-07-12 LinkOut
At a Glance
Diagnosis; Prognostic
Hereditary thrombophilia; Myocardial infarction; Pregnancy loss, recurrent, susceptibility to, 2
Genes (1): Help
SERPINE1 (7q22.1)
Molecular Genetics - Targeted variant analysis: RT-qPCR
Pregnant woman, thrombophilia, miocardial infarction
Not provided
Not provided
Ordering Information
Offered by: Help
IBC Instituto de Bioquimica Clinica SRL
View lab's website
View lab's test page
Manufacturer's name: Help
PAI 4G/5G
Specimen Source: Help
Who can order: Help
  • Health Care Provider
Test Order Code: Help
PAI 4G/5G
Contact Policy: Help
Pre-test email/phone consultation regarding genetic test results and interpretation is provided to patients/families.
How to Order: Help
Molecular PAI / PAI 4G/5G
Order URL
Test service: Help
Clinical Testing/Confirmation of Mutations Identified Previously
Test additional service: Help
Custom mutation-specific/Carrier testing
Test development: Help
Manufactured (research use only; not FDA-reviewed)
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Conditions Help
Total conditions: 3
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 1
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument
Targeted variant analysis
RT-qPCR
LightCycler 2.0
Clinical Information
Test purpose: Help
Diagnosis; Prognostic
Target population: Help
Pregnant woman, thrombophilia, miocardial infarction
View citations (2)
  • Salazar Garcia MD, Sung N, Mullenix TM, Dambaeva S, Beaman K, Gilman-Sachs A, Kwak-Kim J. Plasminogen Activator Inhibitor-1 4G/5G Polymorphism is Associated with Reproductive Failure: Metabolic, Hormonal, and Immune Profiles. Am J Reprod Immunol. 2016;76(1):70-81. doi:10.1111/aji.12516. Epub 2016 May 04. PMID: 27145077.
  • Polymorphisms Associated with Increased Cardiovascular Risk in the General Population do not Predict Acute Events in Hemodialysis Patients. Rolla R, et al. Clin Lab. 2016;62(4):639-44. doi:10.7754/clin.lab.2015.150813. PMID: 27215083.
Recommended fields not provided:
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
A total number of 132 different genomic DNA samples from individuals of Caucasian origin were analyzed in parallel by sequencing and with the present kit. The study compared results obtained with the kit with ABI 3730xl DNA sequencing data obtained by LGC Genomics GmbH, Berlin. Study results: Results for both … View more
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
internal controls provided

PT Provider: Help
provider - Tibmolbiol
Recommended fields not provided:
Regulatory Approval
FDA Review: Help
Not provided
Additional Information

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