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Female infertility genetic testing
Clinical Genetic Test
Help
offered by
CEN4GEN Institute for Genomics and Molecular Diagnostics
GTR Test Accession: Help GTR000560666.1
INHERITED DISEASE
Last updated in GTR: 2018-03-27
View version history
Last annual review date for the lab: 2023-12-05 LinkOut
At a Glance
Test purpose: Help
Diagnosis; Risk Assessment; Mutation Confirmation
Conditions (1): Help
Hereditary disease
Genes (6): Help
BMP15 (Xp11.22), FMR1 (Xq27.3), FSHR (2p16.3), LHB (19q13.33), LHCGR (2p16.3), ...
Methods (3): Help
Cytogenetics - Karyotyping: G-banding; ...
Target population: Help
This comprehensive test is indicated for the diagnosis of female …
Clinical validity: Help
Not provided
Clinical utility: Help
Not provided
Ordering Information
Offered by: Help
CEN4GEN Institute for Genomics and Molecular Diagnostics
View lab's website
Specimen Source: Help
Who can order: Help
  • Health Care Provider
Test Order Code: Help
8743
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Order URL
Informed consent required: Help
Yes
Pre-test genetic counseling required: Help
No
Post-test genetic counseling required: Help
No
Recommended fields not provided:
Lab contact for this test, Test strategy, Test development
Conditions Help
Total conditions: 1
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 6
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 3
Method Category Help
Test method Help
Instrument *
Karyotyping
G-banding
Microsatellite instability testing (MSI)
Trinucleotide repeat by PCR or Southern Blot
Sequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
* Instrument: Not provided
Clinical Information
Test purpose: Help
Diagnosis; Risk Assessment; Mutation Confirmation
Target population: Help
This comprehensive test is indicated for the diagnosis of female infertility, and involves: 1) mosaic chromosome analysis 2) FMR1 trinucleotide repeat analysis 3) Full gene sequencing of genes implicated in female infertility Contact CEN4GEN for more information.
Recommended fields not provided:
Clinical validity, Clinical utility, What is the protocol for interpreting a variation as a VUS?, Are family members with defined clinical status recruited to assess significance of VUS without charge?, Will the lab re-contact the ordering physician if variant interpretation changes?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
The analytical validity for this analysis is 99%.
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
No
Recommended fields not provided:
Test Confirmation, Assay limitations, Description of internal test validation method, Citations for Analytical validity, PT Provider, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Category: Not Applicable
Additional Information
Practice guidelines:
Consumer resources:

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.