Cardiology Sequencing- Arrhythmia Comprehensive Panel (134 Genes)
Clinical Genetic Test
Help
offered by
GTR Test Accession: Help GTR000607975.1
CAP
INHERITED DISEASEMUSCULOSKELETALCARDIOVASCULAR ... View more
Last updated in GTR: 2023-08-15
Last annual review date for the lab: 2023-08-03 LinkOut
At a Glance
Diagnosis; Mutation Confirmation; Risk Assessment; ...
Atrial fibrillation, familial, 13; 3-Methylglutaconic aciduria type 2; 3-methylglutaconic aciduria type 5; ...
ABCC9 (12p12.1), ACTA1 (1q42.13), ACTC1 (15q14), ACTN2 (1q43), AKAP9 (7q21.2), ...
Molecular Genetics - Mutation scanning of select exons: Next-Generation (NGS)/Massively parallel sequencing (MPS)
The GDI Cardiology Sequencing Panels are recommended for patients that …
Not provided
Guidance for management
Ordering Information
Offered by: Help
Specimen Source: Help
Who can order: Help
  • Health Care Provider
  • Nurse Practitioner
Test Order Code: Help
CARDAR
Informed consent required: Help
Yes
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Conditions Help
Total conditions: 88
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 134
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument *
Mutation scanning of select exons
Next-Generation (NGS)/Massively parallel sequencing (MPS)
* Instrument: Not provided
Clinical Information
Test purpose: Help
Diagnosis; Mutation Confirmation; Risk Assessment; Screening
Clinical utility: Help
Guidance for management
View citations (1)
  • Next-Generation Sequencing in Cardiovascular Disease: Present Clinical Applications and the Horizon of Precision Medicine. Parikh VN, et al. Circulation. 2017;135(5):406-409. doi:10.1161/CIRCULATIONAHA.116.024258. PMID: 28137961.

Target population: Help
The GDI Cardiology Sequencing Panels are recommended for patients that are suspected of or are diagnosed with cardiac disorders with a known genetic link, have a family history of cardiac disorders, or have a known familial variant implicated in a gene that is covered by this panel.
Recommended fields not provided:
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
The GDI Cardiac Sequencing Arrhythmia & Cardiomyopathy Comprehensive Panel sequences 134 genes and was validated with a sensitivity and specificity of 96.5 and 100%, respectively.
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Formal PT program

PT Provider: Help
College of American Pathologists, CAP

CAP Testing Information (legacy) Help
Next-Generation Sequencing-Germline; Next-generation sequencing; NGS
Recommended fields not provided:
Regulatory Approval
FDA Review: Help
Not provided
Additional Information

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.