U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Acute myocarditis

MedGen UID:
102339
•Concept ID:
C0155686
•
Disease or Syndrome
Synonyms: Acute Myocarditis; acute myocarditis; myocarditis, acute
SNOMED CT: Acute myocarditis (46701001)
 
Monarch Initiative: MONDO:0002815

Definition

The sudden onset of inflammation of heart muscle with myocellular necrosis; this is generally secondary to an infectious cause, and patients often have a recent history of a flu-like illness. [from NCI]

Professional guidelines

PubMed

Diagnosis and Treatment of Acute Myocarditis: A Review.
Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Acute myocarditis: aetiology, diagnosis and management.
Lampejo T, Durkin SM, Bhatt N, Guttmann O
Clin Med (Lond) 2021 Sep;21(5):e505-e510. doi: 10.7861/clinmed.2021-0121. PMID: 34507935Free PMC Article
Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document.
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article

Recent clinical studies

Etiology

Dengue Myocarditis: A Case Report and Major Review.
Cristodulo R, Luoma-Overstreet G, Leite F, Vaca M, Navia M, Durán G, Molina F, Zonneveld B, Perrone SV, Barbagelata A, Kaplinsky E
Glob Heart 2023;18(1):41. Epub 2023 Aug 4 doi: 10.5334/gh.1254. PMID: 37547170Free PMC Article
Acute myocarditis after COVID-19 vaccination.
Saadi SM, Bossei AA, Alsulimani LK
Saudi Med J 2022 Nov;43(11):1270-1275. doi: 10.15537/smj.2022.43.11.20220292. PMID: 36379527Free PMC Article
Update on acute myocarditis.
Ammirati E, Veronese G, Bottiroli M, Wang DW, Cipriani M, Garascia A, Pedrotti P, Adler ED, Frigerio M
Trends Cardiovasc Med 2021 Aug;31(6):370-379. Epub 2020 Jun 1 doi: 10.1016/j.tcm.2020.05.008. PMID: 32497572Free PMC Article
Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document.
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article
Myocarditis.
Sagar S, Liu PP, Cooper LT Jr
Lancet 2012 Feb 25;379(9817):738-47. Epub 2011 Dec 18 doi: 10.1016/S0140-6736(11)60648-X. PMID: 22185868Free PMC Article

Diagnosis

Acute myocarditis: An urgent need for evidence-based recommendations.
Bohbot Y, Pezel T
Arch Cardiovasc Dis 2024 Jun-Jul;117(6-7):379-381. Epub 2024 May 18 doi: 10.1016/j.acvd.2024.05.116. PMID: 38797640
Chlamydia psittaci-related pleuro-myocarditis.
Sreiri N, Ben Abdallah Y, Belfeki N, Klopfenstein T, Zayet S
Braz J Infect Dis 2024 Mar-Apr;28(2):103739. Epub 2024 Apr 26 doi: 10.1016/j.bjid.2024.103739. PMID: 38679059Free PMC Article
Diagnosis and Treatment of Acute Myocarditis: A Review.
Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Acute myocarditis: aetiology, diagnosis and management.
Lampejo T, Durkin SM, Bhatt N, Guttmann O
Clin Med (Lond) 2021 Sep;21(5):e505-e510. doi: 10.7861/clinmed.2021-0121. PMID: 34507935Free PMC Article
Acute myocarditis in children.
Simpson KE, Canter CE
Expert Rev Cardiovasc Ther 2011 Jun;9(6):771-83. doi: 10.1586/erc.11.70. PMID: 21714608

Therapy

Diagnosis and Treatment of Acute Myocarditis: A Review.
Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Acute myocarditis after COVID-19 vaccination.
Saadi SM, Bossei AA, Alsulimani LK
Saudi Med J 2022 Nov;43(11):1270-1275. doi: 10.15537/smj.2022.43.11.20220292. PMID: 36379527Free PMC Article
Update on acute myocarditis.
Ammirati E, Veronese G, Bottiroli M, Wang DW, Cipriani M, Garascia A, Pedrotti P, Adler ED, Frigerio M
Trends Cardiovasc Med 2021 Aug;31(6):370-379. Epub 2020 Jun 1 doi: 10.1016/j.tcm.2020.05.008. PMID: 32497572Free PMC Article
Acute myocarditis by enzalutamide.
Ramos Reyes V, Laynez Carnicero A, Morales M
Med Clin (Barc) 2021 Apr 9;156(7):359. Epub 2020 May 20 doi: 10.1016/j.medcli.2020.02.017. PMID: 32444324
Personalized medicine in inflammatory cardiomyopathy.
Neupane B, Zhou Q, Gawaz M, Gramlich M
Per Med 2018 Mar;15(2):127-136. Epub 2018 Feb 2 doi: 10.2217/pme-2017-0074. PMID: 29714129

Prognosis

Diagnosis and Treatment of Acute Myocarditis: A Review.
Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Acute myocarditis: aetiology, diagnosis and management.
Lampejo T, Durkin SM, Bhatt N, Guttmann O
Clin Med (Lond) 2021 Sep;21(5):e505-e510. doi: 10.7861/clinmed.2021-0121. PMID: 34507935Free PMC Article
Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document.
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article
Myocarditis: imaging up to date.
Liguori C, Farina D, Vaccher F, Ferrandino G, Bellini D, Carbone I
Radiol Med 2020 Nov;125(11):1124-1134. Epub 2020 Oct 6 doi: 10.1007/s11547-020-01279-8. PMID: 33025305Free PMC Article
Myocarditis.
Sagar S, Liu PP, Cooper LT Jr
Lancet 2012 Feb 25;379(9817):738-47. Epub 2011 Dec 18 doi: 10.1016/S0140-6736(11)60648-X. PMID: 22185868Free PMC Article

Clinical prediction guides

Chlamydia psittaci-related pleuro-myocarditis.
Sreiri N, Ben Abdallah Y, Belfeki N, Klopfenstein T, Zayet S
Braz J Infect Dis 2024 Mar-Apr;28(2):103739. Epub 2024 Apr 26 doi: 10.1016/j.bjid.2024.103739. PMID: 38679059Free PMC Article
Diagnosis and Treatment of Acute Myocarditis: A Review.
Ammirati E, Moslehi JJ
JAMA 2023 Apr 4;329(13):1098-1113. doi: 10.1001/jama.2023.3371. PMID: 37014337
Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document.
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article
Orally-transmitted Chagas disease.
Filigheddu MT, Górgolas M, Ramos JM
Med Clin (Barc) 2017 Feb 9;148(3):125-131. Epub 2016 Dec 16 doi: 10.1016/j.medcli.2016.10.038. PMID: 27993415
Myocarditis.
Sagar S, Liu PP, Cooper LT Jr
Lancet 2012 Feb 25;379(9817):738-47. Epub 2011 Dec 18 doi: 10.1016/S0140-6736(11)60648-X. PMID: 22185868Free PMC Article

Recent systematic reviews

Prevalence of Pathogenic Variants in Cardiomyopathy-Associated Genes in Acute Myocarditis: A Systematic Review and Meta-Analysis.
Monda E, Bakalakos A, Cannie D, O'Mahony C, Syrris P, Kaski JP, Limongelli G, Elliott PM
JACC Heart Fail 2024 Jun;12(6):1101-1111. Epub 2024 Apr 3 doi: 10.1016/j.jchf.2024.02.012. PMID: 38573261
Cardiac Manifestations of Viral Infections, Including COVID-19: A Review.
Weisleder H, Jacobson E, Frishman WH, Dhand A
Cardiol Rev 2024 Mar-Apr 01;32(2):124-130. Epub 2022 Nov 21 doi: 10.1097/CRD.0000000000000481. PMID: 36730913
Corticosteroid in anti-inflammatory treatment of pediatric acute myocarditis: a systematic review and meta-analysis.
Yao Q, Zhan S
Ital J Pediatr 2023 Mar 13;49(1):30. doi: 10.1186/s13052-023-01423-w. PMID: 36915162Free PMC Article
One-Year Risk of Myocarditis After COVID-19 Infection: A Systematic Review and Meta-analysis.
Zuin M, Rigatelli G, Bilato C, Porcari A, Merlo M, Roncon L, Sinagra G
Can J Cardiol 2023 Jun;39(6):839-844. Epub 2022 Dec 12 doi: 10.1016/j.cjca.2022.12.003. PMID: 36521730Free PMC Article
Cocaine and coronary artery diseases: a systematic review of the literature.
Talarico GP, Crosta ML, Giannico MB, Summaria F, Calò L, Patrizi R
J Cardiovasc Med (Hagerstown) 2017 May;18(5):291-294. doi: 10.2459/JCM.0000000000000511. PMID: 28306693

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...