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Elevated circulating acetylcarnitine concentration

MedGen UID:
1047787
•Concept ID:
CN372792
•
Finding
Synonym: Elevated circulating C2 acylcarnitine concentration
 
HPO: HP:0035023

Definition

Concentration of acetylcarnitine (C2 acylcarnitine) in the blood circulation above the upper limit of normal. Acetylcarnitine has a two-carbon acyl chain. [from HPO]

Recent clinical studies

Etiology

Acetyl-L-Carnitine Ameliorates Metabolic and Endocrine Alterations in Women with PCOS: A Double-Blind Randomized Clinical Trial.
Tauqir S, Israr M, Rauf B, Malik MO, Habib SH, Shah FA, Usman M, Raza MA, Shah I, Badshah H, Ehtesham E, Shah M
Adv Ther 2021 Jul;38(7):3842-3856. Epub 2021 May 28 doi: 10.1007/s12325-021-01789-5. PMID: 34047916
Carnitine-related alterations in patients with intermittent claudication: indication for a focused carnitine therapy.
Brevetti G, di Lisa F, Perna S, Menabó R, Barbato R, Martone VD, Siliprandi N
Circulation 1996 May 1;93(9):1685-9. doi: 10.1161/01.cir.93.9.1685. PMID: 8653874

Therapy

Dynamic Metabolic Signatures of Choline and Carnitine across Healthy Pregnancy and in Cord Blood: Association with Maternal Dietary Protein.
Shanmuganathan M, Bogert M, Kroezen Z, Britz-McKibbin P, Atkinson SA
J Nutr 2023 Apr;153(4):999-1007. Epub 2023 Feb 11 doi: 10.1016/j.tjnut.2023.02.013. PMID: 36780943
Acetyl-L-Carnitine Ameliorates Metabolic and Endocrine Alterations in Women with PCOS: A Double-Blind Randomized Clinical Trial.
Tauqir S, Israr M, Rauf B, Malik MO, Habib SH, Shah FA, Usman M, Raza MA, Shah I, Badshah H, Ehtesham E, Shah M
Adv Ther 2021 Jul;38(7):3842-3856. Epub 2021 May 28 doi: 10.1007/s12325-021-01789-5. PMID: 34047916
Carnitine-related alterations in patients with intermittent claudication: indication for a focused carnitine therapy.
Brevetti G, di Lisa F, Perna S, Menabó R, Barbato R, Martone VD, Siliprandi N
Circulation 1996 May 1;93(9):1685-9. doi: 10.1161/01.cir.93.9.1685. PMID: 8653874

Clinical prediction guides

Acetyl-L-Carnitine Ameliorates Metabolic and Endocrine Alterations in Women with PCOS: A Double-Blind Randomized Clinical Trial.
Tauqir S, Israr M, Rauf B, Malik MO, Habib SH, Shah FA, Usman M, Raza MA, Shah I, Badshah H, Ehtesham E, Shah M
Adv Ther 2021 Jul;38(7):3842-3856. Epub 2021 May 28 doi: 10.1007/s12325-021-01789-5. PMID: 34047916
Carnitine-related alterations in patients with intermittent claudication: indication for a focused carnitine therapy.
Brevetti G, di Lisa F, Perna S, Menabó R, Barbato R, Martone VD, Siliprandi N
Circulation 1996 May 1;93(9):1685-9. doi: 10.1161/01.cir.93.9.1685. PMID: 8653874

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