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Epiglottic enlargement

MedGen UID:
1052509
•Concept ID:
CN377100
•
Finding
Synonyms: Epiglottis thumb sign; Swollen epiglottis
 
HPO: HP:6000289

Definition

Anlarged and edematous epiglottis. This sign can be observed on a lateral radiograph of the neck and it suggests a diagnosis of acute infectious epiglottitis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpiglottic enlargement

Professional guidelines

PubMed

Changes of epiglottis and hyoid bone position after orthodontic treatment with cast splint fixed functional appliances.
Hourfar J, Lisson JA, Kinzinger GSM
Clin Oral Investig 2021 Mar;25(3):1525-1534. Epub 2021 Jan 6 doi: 10.1007/s00784-020-03460-9. PMID: 33409688
Primary and salvage laser surgery of 341 glottic cancers-Comparison of treatment outcomes between University Head Neck Tertiary Referral Center and Local Head Neck Department.
Winiarski P, Lewandowski A, Greczka G, Banaszewski J, Klimza H, Wierzbicka M
Lasers Surg Med 2018 Apr;50(4):311-318. Epub 2017 Nov 14 doi: 10.1002/lsm.22759. PMID: 29135033
The diagnosis and management of globus: a perspective from Belgium.
Remacle M
Curr Opin Otolaryngol Head Neck Surg 2008 Dec;16(6):511-5. doi: 10.1097/moo.0b013e328313bb94. PMID: 19023906

Recent clinical studies

Etiology

Value of high resolution ultrasonography in assessment of laryngeal lesions.
Gomaa MA, Hammad MS, Mamdoh H, Osman N, Eissawy MG
Otolaryngol Pol 2013 Sep-Oct;67(5):252-6. Epub 2013 Jun 7 doi: 10.1016/j.otpol.2013.06.001. PMID: 24021828
Pharyngography after head and neck irradiation: differentiation of postirradiation edema from recurrent tumor.
Quillin SP, Balfe DM, Glick SN
AJR Am J Roentgenol 1993 Dec;161(6):1205-8. doi: 10.2214/ajr.161.6.8249726. PMID: 8249726

Diagnosis

Value of high resolution ultrasonography in assessment of laryngeal lesions.
Gomaa MA, Hammad MS, Mamdoh H, Osman N, Eissawy MG
Otolaryngol Pol 2013 Sep-Oct;67(5):252-6. Epub 2013 Jun 7 doi: 10.1016/j.otpol.2013.06.001. PMID: 24021828
Graft-vs-host disease as a cause of enlargement of the epiglottis in an immunocompromised child.
de Diego JI, Prim MP, Hardisson D, del Palacio AJ, Rabanal I
Arch Otolaryngol Head Neck Surg 2001 Apr;127(4):439-41. doi: 10.1001/archotol.127.4.439. PMID: 11296055
Epiglottic enlargement secondary to laryngeal sarcoidosis.
McHugh K, deSilva M, Kilham HA
Pediatr Radiol 1993;23(1):71. doi: 10.1007/BF02020233. PMID: 8469603
Pharyngography after head and neck irradiation: differentiation of postirradiation edema from recurrent tumor.
Quillin SP, Balfe DM, Glick SN
AJR Am J Roentgenol 1993 Dec;161(6):1205-8. doi: 10.2214/ajr.161.6.8249726. PMID: 8249726
The enlarged epiglottis.
Watts FB Jr, Slovis TL
Pediatr Radiol 1977 Mar 17;5(3):133-6. doi: 10.1007/BF00973977. PMID: 846759

Therapy

Epiglottic enlargement: two unusual causes.
Herman TE, McAlister WH
Pediatr Radiol 1991;21(2):139-40. doi: 10.1007/BF02015631. PMID: 2027720
Epiglottic enlargement in infants and children: another radiologic look.
McCook TA, Kirks DR
Pediatr Radiol 1982;12(5):227-34. doi: 10.1007/BF00971769. PMID: 7177731

Prognosis

Pharyngography after head and neck irradiation: differentiation of postirradiation edema from recurrent tumor.
Quillin SP, Balfe DM, Glick SN
AJR Am J Roentgenol 1993 Dec;161(6):1205-8. doi: 10.2214/ajr.161.6.8249726. PMID: 8249726

Clinical prediction guides

Pharyngography after head and neck irradiation: differentiation of postirradiation edema from recurrent tumor.
Quillin SP, Balfe DM, Glick SN
AJR Am J Roentgenol 1993 Dec;161(6):1205-8. doi: 10.2214/ajr.161.6.8249726. PMID: 8249726

Supplemental Content

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