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Abnormal circulating interleukin 6 concentration

MedGen UID:
1052623
Concept ID:
CN377043
Finding
HPO: HP:6000441

Definition

Any deviation from the normal range of the concentration of interleukin 6 (IL-6) in the blood circulation. [from HPO]

Recent clinical studies

Etiology

Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
Soltani Khaboushan A, Moeinafshar A, Ersi MH, Teixeira AL, Majidi Zolbin M, Kajbafzadeh AM
J Neuroimmunol 2023 Dec 15;385:578243. Epub 2023 Nov 13 doi: 10.1016/j.jneuroim.2023.578243. PMID: 37984118
Griffiths SL, Upthegrove R, Corsi-Zuelli F, Deakin B
Curr Top Behav Neurosci 2023;63:475-497. doi: 10.1007/7854_2022_399. PMID: 36409457
Carvajal Alegria G, Devauchelle-Pensec V, Renaudineau Y, Saraux A, Pers JO, Cornec D
Rheumatology (Oxford) 2017 Aug 1;56(8):1401-1406. doi: 10.1093/rheumatology/kex169. PMID: 28431111
Schindler E, Photiadis J, Lagudka S, Fink C, Hraska V, Asfour B
Eur J Cardiothorac Surg 2010 Mar;37(3):651-7. Epub 2009 Sep 19 doi: 10.1016/j.ejcts.2009.07.050. PMID: 19766503

Diagnosis

Lazzerini PE, Cupelli M, Cartocci A, Bertolozzi I, Salvini V, Accioli R, Salvadori F, Marzotti T, Verrengia D, Cevenini G, Bisogno S, Bicchi M, Donati G, Bernardini S, Laghi-Pasini F, Acampa M, Capecchi PL, El-Sherif N, Boutjdir M
J Am Heart Assoc 2024 Feb 20;13(4):e032071. Epub 2024 Feb 13 doi: 10.1161/JAHA.123.032071. PMID: 38348789Free PMC Article
Soltani Khaboushan A, Moeinafshar A, Ersi MH, Teixeira AL, Majidi Zolbin M, Kajbafzadeh AM
J Neuroimmunol 2023 Dec 15;385:578243. Epub 2023 Nov 13 doi: 10.1016/j.jneuroim.2023.578243. PMID: 37984118
Carvajal Alegria G, Devauchelle-Pensec V, Renaudineau Y, Saraux A, Pers JO, Cornec D
Rheumatology (Oxford) 2017 Aug 1;56(8):1401-1406. doi: 10.1093/rheumatology/kex169. PMID: 28431111
Miyaoka K, Iwase M, Suzuki R, Kondo G, Watanabe H, Ito D, Nagumo M
J Surg Res 2005 May 15;125(2):144-50. doi: 10.1016/j.jss.2004.12.001. PMID: 15854666
Bartalena L, Grasso L, Brogioni S, Aghini-Lombardi F, Braverman LE, Martino E
J Clin Endocrinol Metab 1994 Feb;78(2):423-7. doi: 10.1210/jcem.78.2.8106631. PMID: 8106631

Therapy

Soltani Khaboushan A, Moeinafshar A, Ersi MH, Teixeira AL, Majidi Zolbin M, Kajbafzadeh AM
J Neuroimmunol 2023 Dec 15;385:578243. Epub 2023 Nov 13 doi: 10.1016/j.jneuroim.2023.578243. PMID: 37984118
Carvajal Alegria G, Devauchelle-Pensec V, Renaudineau Y, Saraux A, Pers JO, Cornec D
Rheumatology (Oxford) 2017 Aug 1;56(8):1401-1406. doi: 10.1093/rheumatology/kex169. PMID: 28431111
Schindler E, Photiadis J, Lagudka S, Fink C, Hraska V, Asfour B
Eur J Cardiothorac Surg 2010 Mar;37(3):651-7. Epub 2009 Sep 19 doi: 10.1016/j.ejcts.2009.07.050. PMID: 19766503
Miyaoka K, Iwase M, Suzuki R, Kondo G, Watanabe H, Ito D, Nagumo M
J Surg Res 2005 May 15;125(2):144-50. doi: 10.1016/j.jss.2004.12.001. PMID: 15854666
Bartalena L, Grasso L, Brogioni S, Aghini-Lombardi F, Braverman LE, Martino E
J Clin Endocrinol Metab 1994 Feb;78(2):423-7. doi: 10.1210/jcem.78.2.8106631. PMID: 8106631

Prognosis

He Z, Chen Y, Chen P, Wu G, Cai S
Respirology 2010 Apr;15(3):478-84. Epub 2010 Feb 24 doi: 10.1111/j.1440-1843.2010.01709.x. PMID: 20210891
Schindler E, Photiadis J, Lagudka S, Fink C, Hraska V, Asfour B
Eur J Cardiothorac Surg 2010 Mar;37(3):651-7. Epub 2009 Sep 19 doi: 10.1016/j.ejcts.2009.07.050. PMID: 19766503
Miyaoka K, Iwase M, Suzuki R, Kondo G, Watanabe H, Ito D, Nagumo M
J Surg Res 2005 May 15;125(2):144-50. doi: 10.1016/j.jss.2004.12.001. PMID: 15854666
Hoen S, Asehnoune K, Brailly-Tabard S, Mazoit JX, Benhamou D, Moine P, Edouard AR
Anesthesiology 2002 Oct;97(4):807-13. doi: 10.1097/00000542-200210000-00010. PMID: 12357144
Lommi J, Kupari M, Koskinen P, Näveri H, Leinonen H, Pulkki K, Härkönen M
J Am Coll Cardiol 1996 Sep;28(3):665-72. doi: 10.1016/0735-1097(96)00214-8. PMID: 8772754

Clinical prediction guides

Lazzerini PE, Cupelli M, Cartocci A, Bertolozzi I, Salvini V, Accioli R, Salvadori F, Marzotti T, Verrengia D, Cevenini G, Bisogno S, Bicchi M, Donati G, Bernardini S, Laghi-Pasini F, Acampa M, Capecchi PL, El-Sherif N, Boutjdir M
J Am Heart Assoc 2024 Feb 20;13(4):e032071. Epub 2024 Feb 13 doi: 10.1161/JAHA.123.032071. PMID: 38348789Free PMC Article
Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
Bester J, Matshailwe C, Pretorius E
Cytokine 2018 Oct;110:237-242. Epub 2018 Feb 1 doi: 10.1016/j.cyto.2018.01.007. PMID: 29396046
Carvajal Alegria G, Devauchelle-Pensec V, Renaudineau Y, Saraux A, Pers JO, Cornec D
Rheumatology (Oxford) 2017 Aug 1;56(8):1401-1406. doi: 10.1093/rheumatology/kex169. PMID: 28431111
Miyaoka K, Iwase M, Suzuki R, Kondo G, Watanabe H, Ito D, Nagumo M
J Surg Res 2005 May 15;125(2):144-50. doi: 10.1016/j.jss.2004.12.001. PMID: 15854666

Recent systematic reviews

Soltani Khaboushan A, Moeinafshar A, Ersi MH, Teixeira AL, Majidi Zolbin M, Kajbafzadeh AM
J Neuroimmunol 2023 Dec 15;385:578243. Epub 2023 Nov 13 doi: 10.1016/j.jneuroim.2023.578243. PMID: 37984118

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