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Malignant pleural effusion

MedGen UID:
1052669
Concept ID:
CN378426
Finding
Synonym: Malignant cells in pleural fluid
 
HPO: HP:6001078

Definition

The accumulation of a significant amount of exudate in the pleural space, accompanied by the presence of malignant cells or tumour tissue. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant pleural effusion

Professional guidelines

PubMed

Gayen S
Am J Med 2022 Oct;135(10):1188-1192. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.017. PMID: 35576996
Ferreiro L, Suárez-Antelo J, Álvarez-Dobaño JM, Toubes ME, Riveiro V, Valdés L
Can Respir J 2020;2020:2950751. Epub 2020 Sep 23 doi: 10.1155/2020/2950751. PMID: 33273991Free PMC Article
Jany B, Welte T
Dtsch Arztebl Int 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377. PMID: 31315808Free PMC Article

Recent clinical studies

Etiology

Wang S, Tian S, Li Y, Zhan N, Guo Y, Liu Y, Xu J, Ma Y, Zhang S, Song S, Geng W, Xia H, Ma P, Wang X, Liao T, Duan Y, Jin Y, Dong W
EBioMedicine 2020 Aug;58:102924. Epub 2020 Jul 30 doi: 10.1016/j.ebiom.2020.102924. PMID: 32739872Free PMC Article
Thomas R, Fysh ETH, Smith NA, Lee P, Kwan BCH, Yap E, Horwood FC, Piccolo F, Lam DCL, Garske LA, Shrestha R, Kosky C, Read CA, Murray K, Lee YCG
JAMA 2017 Nov 21;318(19):1903-1912. doi: 10.1001/jama.2017.17426. PMID: 29164255Free PMC Article
Walker S, Bibby AC, Maskell NA
Ther Adv Respir Dis 2017 Feb;11(2):105-114. Epub 2016 Oct 24 doi: 10.1177/1753465816671697. PMID: 27777372Free PMC Article
Roberts ME, Neville E, Berrisford RG, Antunes G, Ali NJ; BTS Pleural Disease Guideline Group
Thorax 2010 Aug;65 Suppl 2:ii32-40. doi: 10.1136/thx.2010.136994. PMID: 20696691
Antony VB, Loddenkemper R, Astoul P, Boutin C, Goldstraw P, Hott J, Rodriguez Panadero F, Sahn SA
Eur Respir J 2001 Aug;18(2):402-19. doi: 10.1183/09031936.01.00225601. PMID: 11529302

Diagnosis

Gonnelli F, Hassan W, Bonifazi M, Pinelli V, Bedawi EO, Porcel JM, Rahman NM, Mei F
Respir Res 2024 Jan 19;25(1):47. doi: 10.1186/s12931-024-02684-7. PMID: 38243259Free PMC Article
Gayen S
Am J Med 2022 Oct;135(10):1188-1192. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.017. PMID: 35576996
Ferreiro L, Suárez-Antelo J, Álvarez-Dobaño JM, Toubes ME, Riveiro V, Valdés L
Can Respir J 2020;2020:2950751. Epub 2020 Sep 23 doi: 10.1155/2020/2950751. PMID: 33273991Free PMC Article
Jany B, Welte T
Dtsch Arztebl Int 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377. PMID: 31315808Free PMC Article
Villena Garrido V, Cases Viedma E, Fernández Villar A, de Pablo Gafas A, Pérez Rodríguez E, Porcel Pérez JM, Rodríguez Panadero F, Ruiz Martínez C, Salvatierra Velázquez A, Valdés Cuadrado L
Arch Bronconeumol 2014 Jun;50(6):235-49. Epub 2014 Mar 31 doi: 10.1016/j.arbres.2014.01.016. PMID: 24698396

Therapy

Lamb C, Li A, Thakkar D, Lee P
Semin Respir Crit Care Med 2019 Jun;40(3):375-385. Epub 2019 Sep 16 doi: 10.1055/s-0039-1693997. PMID: 31525812
Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA
Am J Respir Crit Care Med 2018 Oct 1;198(7):839-849. doi: 10.1164/rccm.201807-1415ST. PMID: 30272503
Roberts ME, Neville E, Berrisford RG, Antunes G, Ali NJ; BTS Pleural Disease Guideline Group
Thorax 2010 Aug;65 Suppl 2:ii32-40. doi: 10.1136/thx.2010.136994. PMID: 20696691
Shuey K, Payne Y
Clin J Oncol Nurs 2005 Oct;9(5):529-32. doi: 10.1188/05.CJON.529-532. PMID: 16235579
Br Med J 1968 Jul 27;3(5612):202. PMID: 5662973Free PMC Article

Prognosis

Pan CX, Palathra BC, Leo-To WF
Med Clin North Am 2020 May;104(3):455-470. Epub 2020 Feb 20 doi: 10.1016/j.mcna.2019.12.004. PMID: 32312409
Skok K, Hladnik G, Grm A, Crnjac A
Medicina (Kaunas) 2019 Aug 15;55(8) doi: 10.3390/medicina55080490. PMID: 31443309Free PMC Article
Singh H, Pannu AK, Suri V, Bhalla A, Kumari S
QJM 2019 Feb 1;112(2):135-136. doi: 10.1093/qjmed/hcy191. PMID: 30165695
Egan AM, McPhillips D, Sarkar S, Breen DP
QJM 2014 Mar;107(3):179-84. Epub 2013 Dec 24 doi: 10.1093/qjmed/hct245. PMID: 24368856
Ismail-Khan R, Robinson LA, Williams CC Jr, Garrett CR, Bepler G, Simon GR
Cancer Control 2006 Oct;13(4):255-63. doi: 10.1177/107327480601300402. PMID: 17075562

Clinical prediction guides

Garcia-Pachon E, Soler-Sempere MJ, Zamora-Molina L, Baeza-Martinez C, Grau-Delgado J, Padilla-Navas I
Clin Lab 2020 Aug 1;66(8) doi: 10.7754/Clin.Lab.2020.191267. PMID: 32776733
Wang S, Tian S, Li Y, Zhan N, Guo Y, Liu Y, Xu J, Ma Y, Zhang S, Song S, Geng W, Xia H, Ma P, Wang X, Liao T, Duan Y, Jin Y, Dong W
EBioMedicine 2020 Aug;58:102924. Epub 2020 Jul 30 doi: 10.1016/j.ebiom.2020.102924. PMID: 32739872Free PMC Article
Skok K, Hladnik G, Grm A, Crnjac A
Medicina (Kaunas) 2019 Aug 15;55(8) doi: 10.3390/medicina55080490. PMID: 31443309Free PMC Article
Bibby AC, Dorn P, Psallidas I, Porcel JM, Janssen J, Froudarakis M, Subotic D, Astoul P, Licht P, Schmid R, Scherpereel A, Rahman NM, Cardillo G, Maskell NA
Eur Respir J 2018 Jul;52(1) Epub 2018 Jul 27 doi: 10.1183/13993003.00349-2018. PMID: 30054348
Walker S, Bibby AC, Maskell NA
Ther Adv Respir Dis 2017 Feb;11(2):105-114. Epub 2016 Oct 24 doi: 10.1177/1753465816671697. PMID: 27777372Free PMC Article

Recent systematic reviews

Kassirian S, Hinton SN, Cuninghame S, Chaudhary R, Iansavitchene A, Amjadi K, Dhaliwal I, Zeman-Pocrnich C, Mitchell MA
Thorax 2023 Jan;78(1):32-40. Epub 2022 Feb 2 doi: 10.1136/thoraxjnl-2021-217959. PMID: 35110369
Martinez-Zayas G, Molina S, Ost DE
Eur Respir Rev 2022 Dec 31;31(166) Epub 2022 Dec 21 doi: 10.1183/16000617.0053-2022. PMID: 36543349Free PMC Article
Beltsios ET, Mavrovounis G, Adamou A, Panagiotopoulos N
Gen Thorac Cardiovasc Surg 2021 May;69(5):832-842. Epub 2020 Nov 22 doi: 10.1007/s11748-020-01549-2. PMID: 33222091
Dipper A, Jones HE, Bhatnagar R, Preston NJ, Maskell N, Clive AO
Cochrane Database Syst Rev 2020 Apr 21;4(4):CD010529. doi: 10.1002/14651858.CD010529.pub3. PMID: 32315458Free PMC Article
Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA
Am J Respir Crit Care Med 2018 Oct 1;198(7):839-849. doi: 10.1164/rccm.201807-1415ST. PMID: 30272503

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