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Abnormality of the lung

MedGen UID:
892303
•Concept ID:
C4021760
•
Anatomical Abnormality
Synonym: Abnormality of lung morphology
 
HPO: HP:0002088

Definition

Any structural anomaly of the lung. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Abnormality of the lung

Professional guidelines

PubMed

Needle-localized thoracoscopic resection of indeterminate pulmonary nodules: impact on management of patients with malignant disease.
Schwarz RE, Posner MC, Plunkett MB, Ferson PF, Keenan RJ, Landreneau RJ
Ann Surg Oncol 1995 Jan;2(1):49-55. doi: 10.1007/BF02303702. PMID: 7834454

Recent clinical studies

Etiology

Fetal imaging of congenital lung lesions with postnatal correlation.
Sintim-Damoa A, Cohen HL
Pediatr Radiol 2022 Sep;52(10):1921-1934. Epub 2022 Aug 25 doi: 10.1007/s00247-022-05465-w. PMID: 36002772
Congenital diaphragmatic hernia.
Zani A, Chung WK, Deprest J, Harting MT, Jancelewicz T, Kunisaki SM, Patel N, Antounians L, Puligandla PS, Keijzer R
Nat Rev Dis Primers 2022 Jun 1;8(1):37. doi: 10.1038/s41572-022-00362-w. PMID: 35650272
Pulmonary hypertension in children with Down syndrome.
Bush D, Galambos C, Dunbar Ivy D
Pediatr Pulmonol 2021 Mar;56(3):621-629. Epub 2020 Feb 12 doi: 10.1002/ppul.24687. PMID: 32049444
Long-term outcomes of congenital lung malformations.
Hall NJ, Stanton MP
Semin Pediatr Surg 2017 Oct;26(5):311-316. Epub 2017 Sep 9 doi: 10.1053/j.sempedsurg.2017.09.001. PMID: 29110827
Congenital pulmonary airway malformations: state-of-the-art review for pediatrician's use.
Leblanc C, Baron M, Desselas E, Phan MH, Rybak A, Thouvenin G, Lauby C, Irtan S
Eur J Pediatr 2017 Dec;176(12):1559-1571. Epub 2017 Oct 19 doi: 10.1007/s00431-017-3032-7. PMID: 29046943

Diagnosis

Management of Congenital Lung Malformations.
Hegde BN, Tsao K, Hirose S
Clin Perinatol 2022 Dec;49(4):907-926. doi: 10.1016/j.clp.2022.08.003. PMID: 36328607
Pulmonary hypertension in children with Down syndrome.
Bush D, Galambos C, Dunbar Ivy D
Pediatr Pulmonol 2021 Mar;56(3):621-629. Epub 2020 Feb 12 doi: 10.1002/ppul.24687. PMID: 32049444
Congenital pulmonary airway malformation: advances and controversies.
Wong KKY, Flake AW, Tibboel D, Rottier RJ, Tam PKH
Lancet Child Adolesc Health 2018 Apr;2(4):290-297. Epub 2018 Feb 17 doi: 10.1016/S2352-4642(18)30035-X. PMID: 30169300
Long-term outcomes of congenital lung malformations.
Hall NJ, Stanton MP
Semin Pediatr Surg 2017 Oct;26(5):311-316. Epub 2017 Sep 9 doi: 10.1053/j.sempedsurg.2017.09.001. PMID: 29110827
Congenital pulmonary airway malformations: state-of-the-art review for pediatrician's use.
Leblanc C, Baron M, Desselas E, Phan MH, Rybak A, Thouvenin G, Lauby C, Irtan S
Eur J Pediatr 2017 Dec;176(12):1559-1571. Epub 2017 Oct 19 doi: 10.1007/s00431-017-3032-7. PMID: 29046943

Therapy

Congenital diaphragmatic hernia.
Zani A, Chung WK, Deprest J, Harting MT, Jancelewicz T, Kunisaki SM, Patel N, Antounians L, Puligandla PS, Keijzer R
Nat Rev Dis Primers 2022 Jun 1;8(1):37. doi: 10.1038/s41572-022-00362-w. PMID: 35650272
Current and Future Treatments in Primary Ciliary Dyskinesia.
Paff T, Omran H, Nielsen KG, Haarman EG
Int J Mol Sci 2021 Sep 11;22(18) doi: 10.3390/ijms22189834. PMID: 34575997Free PMC Article
Congenital diaphragmatic hernia-associated cardiac dysfunction.
Patel N, Massolo AC, Kipfmueller F
Semin Perinatol 2020 Feb;44(1):151168. Epub 2019 Jul 30 doi: 10.1053/j.semperi.2019.07.007. PMID: 31420110
Congenital lobar emphysema: diagnosis and treatment options.
Demir OF, Hangul M, Kose M
Int J Chron Obstruct Pulmon Dis 2019;14:921-928. Epub 2019 May 1 doi: 10.2147/COPD.S170581. PMID: 31118601Free PMC Article
Tuberous sclerosis complex.
Henske EP, Jóźwiak S, Kingswood JC, Sampson JR, Thiele EA
Nat Rev Dis Primers 2016 May 26;2:16035. doi: 10.1038/nrdp.2016.35. PMID: 27226234

Prognosis

Congenital Hepatopulmonary Fusion.
Rocha GMD
Eur J Pediatr Surg 2022 Dec;32(6):477-496. Epub 2022 Aug 26 doi: 10.1055/s-0042-1749213. PMID: 36027900
Fetal imaging of congenital lung lesions with postnatal correlation.
Sintim-Damoa A, Cohen HL
Pediatr Radiol 2022 Sep;52(10):1921-1934. Epub 2022 Aug 25 doi: 10.1007/s00247-022-05465-w. PMID: 36002772
Pulmonary hypertension in children with Down syndrome.
Bush D, Galambos C, Dunbar Ivy D
Pediatr Pulmonol 2021 Mar;56(3):621-629. Epub 2020 Feb 12 doi: 10.1002/ppul.24687. PMID: 32049444
Congenital diaphragmatic hernia.
Kotecha S, Barbato A, Bush A, Claus F, Davenport M, Delacourt C, Deprest J, Eber E, Frenckner B, Greenough A, Nicholson AG, Antón-Pacheco JL, Midulla F
Eur Respir J 2012 Apr;39(4):820-9. Epub 2011 Oct 27 doi: 10.1183/09031936.00066511. PMID: 22034651
Congenital lung malformations.
Andrade CF, Ferreira HP, Fischer GB
J Bras Pneumol 2011 Mar-Apr;37(2):259-71. doi: 10.1590/s1806-37132011000200017. PMID: 21537663

Clinical prediction guides

Pulmonary hypertension in children with Down syndrome.
Bush D, Galambos C, Dunbar Ivy D
Pediatr Pulmonol 2021 Mar;56(3):621-629. Epub 2020 Feb 12 doi: 10.1002/ppul.24687. PMID: 32049444
Congenital lobar emphysema: diagnosis and treatment options.
Demir OF, Hangul M, Kose M
Int J Chron Obstruct Pulmon Dis 2019;14:921-928. Epub 2019 May 1 doi: 10.2147/COPD.S170581. PMID: 31118601Free PMC Article
Long-term outcomes of congenital lung malformations.
Hall NJ, Stanton MP
Semin Pediatr Surg 2017 Oct;26(5):311-316. Epub 2017 Sep 9 doi: 10.1053/j.sempedsurg.2017.09.001. PMID: 29110827
Accessory hemi diaphragm.
Radhakrishnan J, Bean J, Piazza DJ, Chin AC
J Pediatr Surg 2014 Aug;49(8):1326-31. doi: 10.1016/j.jpedsurg.2014.03.005. PMID: 25092100
Congenital diaphragmatic hernia.
Kotecha S, Barbato A, Bush A, Claus F, Davenport M, Delacourt C, Deprest J, Eber E, Frenckner B, Greenough A, Nicholson AG, Antón-Pacheco JL, Midulla F
Eur Respir J 2012 Apr;39(4):820-9. Epub 2011 Oct 27 doi: 10.1183/09031936.00066511. PMID: 22034651

Recent systematic reviews

A systematic review and meta-analysis of long term physical and mental sequelae of COVID-19 pandemic: call for research priority and action.
Zeng N, Zhao YM, Yan W, Li C, Lu QD, Liu L, Ni SY, Mei H, Yuan K, Shi L, Li P, Fan TT, Yuan JL, Vitiello MV, Kosten T, Kondratiuk AL, Sun HQ, Tang XD, Liu MY, Lalvani A, Shi J, Bao YP, Lu L
Mol Psychiatry 2023 Jan;28(1):423-433. Epub 2022 Jun 6 doi: 10.1038/s41380-022-01614-7. PMID: 35668159Free PMC Article
A Systematic Review of the Progression of Cutaneous Lupus to Systemic Lupus Erythematosus.
Curtiss P, Walker AM, Chong BF
Front Immunol 2022;13:866319. Epub 2022 Mar 11 doi: 10.3389/fimmu.2022.866319. PMID: 35359921Free PMC Article
Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review.
Groff D, Sun A, Ssentongo AE, Ba DM, Parsons N, Poudel GR, Lekoubou A, Oh JS, Ericson JE, Ssentongo P, Chinchilli VM
JAMA Netw Open 2021 Oct 1;4(10):e2128568. doi: 10.1001/jamanetworkopen.2021.28568. PMID: 34643720Free PMC Article
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Shankar-Hari M, Phillips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, Angus DC, Rubenfeld GD, Singer M; Sepsis Definitions Task Force
JAMA 2016 Feb 23;315(8):775-87. doi: 10.1001/jama.2016.0289. PMID: 26903336Free PMC Article
Short and long term health effects of parental tobacco smoking during pregnancy and lactation: a descriptive review.
Banderali G, Martelli A, Landi M, Moretti F, Betti F, Radaelli G, Lassandro C, Verduci E
J Transl Med 2015 Oct 15;13:327. doi: 10.1186/s12967-015-0690-y. PMID: 26472248Free PMC Article

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