U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal positive emotional state

MedGen UID:
1052888
•Concept ID:
CN378223
•
Finding
Synonym: Positive emotion disturbance
 
HPO: HP:0025767

Definition

Persistent and pathologically elevated emotional experiences, preoccupations, or internal state that may arise spontaneously or may be related to positive perceptions of self, the world, and the future. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal positive emotional state

Professional guidelines

PubMed

Patterns of anxiety and distress over 12 months following participation in HPV primary screening.
Marlow LAV, McBride E, Ridout D, Forster AS, Kitchener H, Waller J
Sex Transm Infect 2022 Jun;98(4):255-261. Epub 2021 Aug 3 doi: 10.1136/sextrans-2020-054780. PMID: 34344834Free PMC Article
Healthcare and psychosocial experiences of individuals with craniofacial microsomia: Patient and caregivers perspectives.
Luquetti DV, Brajcich MR, Stock NM, Heike CL, Johns AL
Int J Pediatr Otorhinolaryngol 2018 Apr;107:164-175. Epub 2018 Feb 7 doi: 10.1016/j.ijporl.2018.02.007. PMID: 29501301Free PMC Article
Differential neural reward mechanisms in treatment-responsive and treatment-resistant schizophrenia.
Vanes LD, Mouchlianitis E, Collier T, Averbeck BB, Shergill SS
Psychol Med 2018 Oct;48(14):2418-2427. Epub 2018 Feb 14 doi: 10.1017/S0033291718000041. PMID: 29439750Free PMC Article

Recent clinical studies

Etiology

Resting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms.
Feng L, Wu D, Ma S, Dong L, Yue Y, Li T, Tang Y, Ye Z, Mao G
BMC Psychiatry 2023 Oct 10;23(1):732. doi: 10.1186/s12888-023-05232-7. PMID: 37817133Free PMC Article
Emotion attribution in intermittent explosive disorder.
Patoilo MS, Berman ME, Coccaro EF
Compr Psychiatry 2021 Apr;106:152229. Epub 2021 Feb 1 doi: 10.1016/j.comppsych.2021.152229. PMID: 33662604
The Effects of Music Intervention on Functional Connectivity Strength of the Brain in Schizophrenia.
Yang M, He H, Duan M, Chen X, Chang X, Lai Y, Li J, Liu T, Luo C, Yao D
Neural Plast 2018;2018:2821832. Epub 2018 May 2 doi: 10.1155/2018/2821832. PMID: 29853841Free PMC Article
Obstructive Sleep Apnea is Linked to Depression and Cognitive Impairment: Evidence and Potential Mechanisms.
Kerner NA, Roose SP
Am J Geriatr Psychiatry 2016 Jun;24(6):496-508. Epub 2016 Apr 29 doi: 10.1016/j.jagp.2016.01.134. PMID: 27139243Free PMC Article
Large-Scale Network Dysfunction in Major Depressive Disorder: A Meta-analysis of Resting-State Functional Connectivity.
Kaiser RH, Andrews-Hanna JR, Wager TD, Pizzagalli DA
JAMA Psychiatry 2015 Jun;72(6):603-11. doi: 10.1001/jamapsychiatry.2015.0071. PMID: 25785575Free PMC Article

Diagnosis

What Can We Learn from Animal Models to Study Schizophrenia?
Crunfli F, Brandão-Teles C, Zuccoli GS, Chaves Filho AJM, Vieira GM, Silva-Amaral D, Crippa JA, Pedrazzi JFC, Macêdo DS, Del-Bel E, Gomes FV
Adv Exp Med Biol 2022;1400:15-33. doi: 10.1007/978-3-030-97182-3_2. PMID: 35930223
Emotion attribution in intermittent explosive disorder.
Patoilo MS, Berman ME, Coccaro EF
Compr Psychiatry 2021 Apr;106:152229. Epub 2021 Feb 1 doi: 10.1016/j.comppsych.2021.152229. PMID: 33662604
Menstrual Health as a Part of Preventive Health Care.
Matteson KA, Zaluski KM
Obstet Gynecol Clin North Am 2019 Sep;46(3):441-453. doi: 10.1016/j.ogc.2019.04.004. PMID: 31378287
Late electrophysiological potentials and emotion in schizophrenia: A meta-analytic review.
Castro MK, Bailey DH, Zinger JF, Martin EA
Schizophr Res 2019 Sep;211:21-31. Epub 2019 Jul 17 doi: 10.1016/j.schres.2019.07.013. PMID: 31324440
Obstructive Sleep Apnea is Linked to Depression and Cognitive Impairment: Evidence and Potential Mechanisms.
Kerner NA, Roose SP
Am J Geriatr Psychiatry 2016 Jun;24(6):496-508. Epub 2016 Apr 29 doi: 10.1016/j.jagp.2016.01.134. PMID: 27139243Free PMC Article

Therapy

Acupuncture modulates emotional network resting-state functional connectivity in patients with insomnia disorder: a randomized controlled trial and fMRI study.
Jiang TF, Chen ZY, Liu J, Yin XJ, Tan ZJ, Wang GL, Li B, Guo J
BMC Complement Med Ther 2024 Aug 21;24(1):311. doi: 10.1186/s12906-024-04612-0. PMID: 39169368Free PMC Article
The Effects of Music Intervention on Functional Connectivity Strength of the Brain in Schizophrenia.
Yang M, He H, Duan M, Chen X, Chang X, Lai Y, Li J, Liu T, Luo C, Yao D
Neural Plast 2018;2018:2821832. Epub 2018 May 2 doi: 10.1155/2018/2821832. PMID: 29853841Free PMC Article
Exercise effects on depression: Possible neural mechanisms.
Gujral S, Aizenstein H, Reynolds CF 3rd, Butters MA, Erickson KI
Gen Hosp Psychiatry 2017 Nov;49:2-10. doi: 10.1016/j.genhosppsych.2017.04.012. PMID: 29122145Free PMC Article
Obstructive Sleep Apnea is Linked to Depression and Cognitive Impairment: Evidence and Potential Mechanisms.
Kerner NA, Roose SP
Am J Geriatr Psychiatry 2016 Jun;24(6):496-508. Epub 2016 Apr 29 doi: 10.1016/j.jagp.2016.01.134. PMID: 27139243Free PMC Article
Neuropsychological mechanism underlying antidepressant effect: a systematic meta-analysis.
Ma Y
Mol Psychiatry 2015 Mar;20(3):311-9. Epub 2014 Mar 25 doi: 10.1038/mp.2014.24. PMID: 24662929

Prognosis

Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress.
Lu J, Zhang X, Su K, Luo H, Liu C, Yang Y, He B, Wang C, Zhao Z, Liu X, Wang X, Meng P, Lv D, Wang C, Kelley KW, Wang L, Cui B, Liu Q, Peng F
Cell Commun Signal 2024 Jul 25;22(1):375. doi: 10.1186/s12964-024-01747-y. PMID: 39054537Free PMC Article
Altered plasma levels of arginine metabolites in depression.
Ozden A, Angelos H, Feyza A, Elizabeth W, John P
J Psychiatr Res 2020 Jan;120:21-28. Epub 2019 Oct 7 doi: 10.1016/j.jpsychires.2019.10.004. PMID: 31629205
The Effects of Music Intervention on Functional Connectivity Strength of the Brain in Schizophrenia.
Yang M, He H, Duan M, Chen X, Chang X, Lai Y, Li J, Liu T, Luo C, Yao D
Neural Plast 2018;2018:2821832. Epub 2018 May 2 doi: 10.1155/2018/2821832. PMID: 29853841Free PMC Article
Thalamocortical connectivity in major depressive disorder.
Brown EC, Clark DL, Hassel S, MacQueen G, Ramasubbu R
J Affect Disord 2017 Aug 1;217:125-131. Epub 2017 Apr 5 doi: 10.1016/j.jad.2017.04.004. PMID: 28407555
A cognitive model of generalized anxiety disorder.
Wells A
Behav Modif 1999 Oct;23(4):526-55. doi: 10.1177/0145445599234002. PMID: 10533439

Clinical prediction guides

Abnormal alterations of regional spontaneous neuronal activity and functional connectivity in insomnia patients with difficulty falling asleep: a resting-state fMRI study.
Jiang T, Yin X, Zhu L, Jia W, Tan Z, Li B, Guo J
BMC Neurol 2023 Dec 4;23(1):430. doi: 10.1186/s12883-023-03481-3. PMID: 38049760Free PMC Article
Resting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms.
Feng L, Wu D, Ma S, Dong L, Yue Y, Li T, Tang Y, Ye Z, Mao G
BMC Psychiatry 2023 Oct 10;23(1):732. doi: 10.1186/s12888-023-05232-7. PMID: 37817133Free PMC Article
The Effects of Music Intervention on Functional Connectivity Strength of the Brain in Schizophrenia.
Yang M, He H, Duan M, Chen X, Chang X, Lai Y, Li J, Liu T, Luo C, Yao D
Neural Plast 2018;2018:2821832. Epub 2018 May 2 doi: 10.1155/2018/2821832. PMID: 29853841Free PMC Article
Exercise effects on depression: Possible neural mechanisms.
Gujral S, Aizenstein H, Reynolds CF 3rd, Butters MA, Erickson KI
Gen Hosp Psychiatry 2017 Nov;49:2-10. doi: 10.1016/j.genhosppsych.2017.04.012. PMID: 29122145Free PMC Article
Sleep apnoea.
Hensley M, Ray C
BMJ Clin Evid 2009 Jun 4;2009 PMID: 21726484Free PMC Article

Recent systematic reviews

Emotional response to testing positive for human papillomavirus at cervical cancer screening: a mixed method systematic review with meta-analysis.
McBride E, Tatar O, Rosberger Z, Rockliffe L, Marlow LAV, Moss-Morris R, Kaur N, Wade K, Waller J
Health Psychol Rev 2021 Sep;15(3):395-429. Epub 2020 May 24 doi: 10.1080/17437199.2020.1762106. PMID: 32449477
Vaginal ring acceptability and related preferences among women in low- and middle-income countries: A systematic review and narrative synthesis.
Griffin JB, Ridgeway K, Montgomery E, Torjesen K, Clark R, Peterson J, Baggaley R, van der Straten A
PLoS One 2019;14(11):e0224898. Epub 2019 Nov 8 doi: 10.1371/journal.pone.0224898. PMID: 31703094Free PMC Article
Screening for HIV in pregnant women: systematic review to update the 2005 U.S. Preventive Services Task Force recommendation.
Chou R, Cantor AG, Zakher B, Bougatsos C
Ann Intern Med 2012 Nov 20;157(10):719-28. doi: 10.7326/0003-4819-157-10-201211200-00009. PMID: 23165663
Mobile phone messaging for communicating results of medical investigations.
Gurol-Urganci I, de Jongh T, Vodopivec-Jamsek V, Car J, Atun R
Cochrane Database Syst Rev 2012 Jun 13;2012(6):CD007456. doi: 10.1002/14651858.CD007456.pub2. PMID: 22696369Free PMC Article
Sleep apnoea.
Hensley M, Ray C
BMJ Clin Evid 2009 Jun 4;2009 PMID: 21726484Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...