U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Euphoria

MedGen UID:
115981
Concept ID:
C0235146
Mental Process
Synonym: Euphorias
SNOMED CT: Euphoria (85949006); Feeling high (307074005)
 
HPO: HP:0031844

Definition

Euphoria is a feeling of intense joy, happiness, excitement, or elation that surpasses what would typically be anticipated in a given situation. [from HPO]

Term Hierarchy

Conditions with this feature

Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1
MedGen UID:
1648386
Concept ID:
C4721893
Disease or Syndrome
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) is characterized by fractures (resulting from radiologically demonstrable polycystic osseous lesions), frontal lobe syndrome, and progressive presenile dementia beginning in the fourth decade. The clinical course of PLOSL can be divided into four stages: 1. The latent stage is characterized by normal early development. 2. The osseous stage (3rd decade of life) is characterized by pain and tenderness, mostly in ankles and feet, usually following strain or injury. Fractures are typically diagnosed several years later, most commonly in the bones of the extremities. 3. In the early neurologic stage (4th decade of life), a change of personality begins to develop insidiously. Affected individuals show a frontal lobe syndrome (loss of judgment, euphoria, loss of social inhibitions, disturbance of concentration, and lack of insight, libido, and motor persistence) leading to serious social problems. 4. The late neurologic stage is characterized by progressive dementia and loss of mobility. Death usually occurs before age 50 years.

Professional guidelines

PubMed

Onakpoya IJ, Thomas ET, Lee JJ, Goldacre B, Heneghan CJ
BMJ Open 2019 Jan 21;9(1):e023600. doi: 10.1136/bmjopen-2018-023600. PMID: 30670513Free PMC Article
Savaskan E, Mueller H, Hoerr R, von Gunten A, Gauthier S
Int Psychogeriatr 2018 Mar;30(3):285-293. Epub 2017 Sep 21 doi: 10.1017/S1041610217001892. PMID: 28931444
Busardò FP, Jones AW
Curr Neuropharmacol 2015 Jan;13(1):47-70. doi: 10.2174/1570159X13666141210215423. PMID: 26074743Free PMC Article

Recent systematic reviews

Meaadi J, Obara I, Eldabe S, Nazar H
Int J Clin Pharm 2023 Jun;45(3):556-565. Epub 2023 Feb 27 doi: 10.1007/s11096-022-01528-y. PMID: 36848024Free PMC Article
Liu J, Wang LN
Cochrane Database Syst Rev 2017 Aug 20;8(8):CD008502. doi: 10.1002/14651858.CD008502.pub5. PMID: 28822350Free PMC Article
Zhao QF, Tan L, Wang HF, Jiang T, Tan MS, Tan L, Xu W, Li JQ, Wang J, Lai TJ, Yu JT
J Affect Disord 2016 Jan 15;190:264-271. Epub 2015 Oct 24 doi: 10.1016/j.jad.2015.09.069. PMID: 26540080
Whiting PF, Wolff RF, Deshpande S, Di Nisio M, Duffy S, Hernandez AV, Keurentjes JC, Lang S, Misso K, Ryder S, Schmidlkofer S, Westwood M, Kleijnen J
JAMA 2015 Jun 23-30;313(24):2456-73. doi: 10.1001/jama.2015.6358. PMID: 26103030
Liu J, Wang LN
Cochrane Database Syst Rev 2015 Apr 3;(4):CD008502. doi: 10.1002/14651858.CD008502.pub4. PMID: 25836263

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...