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Glomus tympanicum paraganglioma

MedGen UID:
105375
Concept ID:
C0474820
Neoplastic Process
Synonyms: Glomus tympanicum tumor; Tympanic paraganglioma
SNOMED CT: Tympanic paraganglioma (253031000); Glomus tympanicum tumor (253031000)
 
Monarch Initiative: MONDO:0023682

Definition

A middle ear paraganglioma arising from paraganglia around the tympanum. Signs and symptoms include a mass behind the tympanum, tinnitus, and conductive hearing loss. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlomus tympanicum paraganglioma

Professional guidelines

PubMed

Shrivastava MK, Curran JF, Sheerin F, Mohammadi BJ, Halliday D, MacKeith SAC
Otol Neurotol 2022 Aug 1;43(7):840-844. Epub 2022 Jul 4 doi: 10.1097/MAO.0000000000003557. PMID: 35802032
Contrera KJ, Yong V, Reddy CA, Liu SW, Lorenz RR
Otolaryngol Head Neck Surg 2020 Apr;162(4):504-511. Epub 2020 Feb 18 doi: 10.1177/0194599820902702. PMID: 32066331
Szymańska A, Szymański M, Czekajska-Chehab E, Gołąbek W, Szczerbo-Trojanowska M
Eur Arch Otorhinolaryngol 2015 Aug;272(8):1991-9. Epub 2014 Jun 12 doi: 10.1007/s00405-014-3126-z. PMID: 24920325Free PMC Article

Recent clinical studies

Etiology

Wu H, Liu X, Wu X, Wu L, Jiang L, Jin Y, He C, Mei L, Song J, Cai X
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Mar 28;48(3):397-403. doi: 10.11817/j.issn.1672-7347.2023.230206. PMID: 37164923
Cass ND, Schopper MA, Lubin JA, Fishbein L, Gubbels SP
Ann Otol Rhinol Laryngol 2020 Nov;129(11):1135-1143. Epub 2020 Jun 2 doi: 10.1177/0003489420931540. PMID: 32486832
Tokgöz SA, Saylam G, Bayır Ö, Keseroğlu K, Toptaş G, Çadallı Tatar E, Akın İ, Korkmaz MH
Acta Otolaryngol 2019 Oct;139(10):930-933. Epub 2019 Aug 27 doi: 10.1080/00016489.2019.1655588. PMID: 31452413
Devuyst L, Defreyne L, Praet M, Geukens S, Dhooge I
Am J Otolaryngol 2016 Nov-Dec;37(6):544-551. Epub 2016 Sep 7 doi: 10.1016/j.amjoto.2016.08.011. PMID: 27650391
Lee CC, Pan DH, Wu JC, Chung WY, Wu HM, Yang HC, Liu KD, Guo WY, Shih YH
Stereotact Funct Neurosurg 2011;89(5):291-8. Epub 2011 Aug 18 doi: 10.1159/000328890. PMID: 21849813

Diagnosis

Leonetti JP
Curr Neurol Neurosci Rep 2022 Aug;22(8):485-489. Epub 2022 Jun 29 doi: 10.1007/s11910-022-01216-4. PMID: 35767145
Sweeney AD, Carlson ML, Wanna GB, Bennett ML
Otolaryngol Clin North Am 2015 Apr;48(2):293-304. Epub 2015 Feb 4 doi: 10.1016/j.otc.2014.12.004. PMID: 25659513
Jackson CG
Otolaryngol Clin North Am 2001 Oct;34(5):941-70, vii. doi: 10.1016/s0030-6665(05)70356-x. PMID: 11557448
Balatsouras DG, Eliopoulos PN, Economou CN
J Laryngol Otol 1992 Jun;106(6):538-43. doi: 10.1017/s0022215100120080. PMID: 1320657
Cole JM
Laryngoscope 1977 Aug;87(8):1244-58. doi: 10.1288/00005537-197708000-00003. PMID: 196144

Therapy

Garg K, Singh M
Neurol India 2023 Mar-Apr;71(Supplement):S153-S160. doi: 10.4103/0028-3886.373640. PMID: 37026347
Noel JE, Sajjadi H
Ear Nose Throat J 2018 Dec;97(12):399-402. doi: 10.1177/014556131809701209. PMID: 30540890
Papaspyrou K, Mewes T, Tóth M, Schmidtmann I, Amedee RG, Mann WJ
Otol Neurotol 2011 Feb;32(2):291-6. doi: 10.1097/MAO.0b013e3182001edb. PMID: 21099727
Sanna M, Fois P, Pasanisi E, Russo A, Bacciu A
Auris Nasus Larynx 2010 Dec;37(6):661-8. Epub 2010 Apr 18 doi: 10.1016/j.anl.2010.03.006. PMID: 20400250
Rohit, Jain Y, Caruso A, Russo A, Sanna M
J Laryngol Otol 2003 Jun;117(6):462-6. doi: 10.1258/002221503321892307. PMID: 12818055

Prognosis

Contrera KJ, Yong V, Reddy CA, Liu SW, Lorenz RR
Otolaryngol Head Neck Surg 2020 Apr;162(4):504-511. Epub 2020 Feb 18 doi: 10.1177/0194599820902702. PMID: 32066331
Sweeney AD, Carlson ML, Wanna GB, Bennett ML
Otolaryngol Clin North Am 2015 Apr;48(2):293-304. Epub 2015 Feb 4 doi: 10.1016/j.otc.2014.12.004. PMID: 25659513
Lee CC, Pan DH, Wu JC, Chung WY, Wu HM, Yang HC, Liu KD, Guo WY, Shih YH
Stereotact Funct Neurosurg 2011;89(5):291-8. Epub 2011 Aug 18 doi: 10.1159/000328890. PMID: 21849813
Sanna M, Fois P, Pasanisi E, Russo A, Bacciu A
Auris Nasus Larynx 2010 Dec;37(6):661-8. Epub 2010 Apr 18 doi: 10.1016/j.anl.2010.03.006. PMID: 20400250
Jackson CG
Otolaryngol Clin North Am 2001 Oct;34(5):941-70, vii. doi: 10.1016/s0030-6665(05)70356-x. PMID: 11557448

Clinical prediction guides

Scheick SM, Morris CG, Amdur RJ, Bova FJ, Friedman WA, Mendenhall WM
Am J Clin Oncol 2018 Mar;41(3):223-226. doi: 10.1097/COC.0000000000000255. PMID: 26650779
Lauretti L, Coli A, Signorelli F, D'Alessandris QG, Fernandez E
Acta Neurochir (Wien) 2016 Apr;158(4):761-766. Epub 2016 Feb 22 doi: 10.1007/s00701-016-2723-6. PMID: 26899970
Szymańska A, Szymański M, Czekajska-Chehab E, Gołąbek W, Szczerbo-Trojanowska M
Eur Arch Otorhinolaryngol 2015 Aug;272(8):1991-9. Epub 2014 Jun 12 doi: 10.1007/s00405-014-3126-z. PMID: 24920325Free PMC Article
Chapman DB, Lippert D, Geer CP, Edwards HD, Russell GB, Rees CJ, Browne JD
Otolaryngol Head Neck Surg 2010 Oct;143(4):531-7. Epub 2010 Aug 16 doi: 10.1016/j.otohns.2010.05.031. PMID: 20869564
Liscák R, Vladyka V, Simonová G, Vymazal J, Janousková L
Stereotact Funct Neurosurg 1998 Oct;70 Suppl 1:152-60. doi: 10.1159/000056417. PMID: 9782246

Recent systematic reviews

Fatima N, Pollom E, Soltys S, Chang SD, Meola A
Neurosurg Rev 2021 Apr;44(2):741-752. Epub 2020 Apr 21 doi: 10.1007/s10143-020-01292-5. PMID: 32318920
Jansen TTG, Timmers HJLM, Marres HAM, Kaanders JHAM, Kunst HPM
Clin Otolaryngol 2018 Apr;43(2):652-661. Epub 2018 Jan 3 doi: 10.1111/coa.13046. PMID: 29222838

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