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Enlarged gastric folds

MedGen UID:
1053892
•Concept ID:
CN376762
•
Finding
Synonym: Giant gastric folds
 
HPO: HP:6000249

Definition

Giant gastric folds are recognized at endoscopy as an increase in the size of the gastric rugae and a lack of flattening. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnlarged gastric folds

Recent clinical studies

Etiology

Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy.
Chatrangsun B, Aumpan N, Pornthisarn B, Chonprasertsuk S, Siramolpiwat S, Bhanthumkomol P, Nunanan P, Issariyakulkarn N, Mahachai V, Yamaoka Y, Vilaichone RK
BMC Gastroenterol 2024 Jan 26;24(1):46. doi: 10.1186/s12876-024-03132-y. PMID: 38273222Free PMC Article
Clinicopathological features and prognosis of developed gastric cancer based on the diagnosis of mucosal atrophy and enlarged folds of stomach by double-contrast upper gastrointestinal barium X-ray radiography.
Yamamichi N, Shimamoto T, Hirano C, Takahashi Y, Minatsuki C, Takeuchi C, Takahashi M, Sakaguchi Y, Tsuji Y, Niimi K, Wada R, Mitsushima T, Koike K
Clin J Gastroenterol 2021 Aug;14(4):947-954. Epub 2021 May 20 doi: 10.1007/s12328-021-01445-z. PMID: 34018155
Atrophic gastritis and enlarged gastric folds diagnosed by double-contrast upper gastrointestinal barium X-ray radiography are useful to predict future gastric cancer development based on the 3-year prospective observation.
Yamamichi N, Hirano C, Ichinose M, Takahashi Y, Minatsuki C, Matsuda R, Nakayama C, Shimamoto T, Kodashima S, Ono S, Tsuji Y, Niimi K, Sakaguchi Y, Kataoka Y, Saito I, Asada-Hirayama I, Takeuchi C, Yakabi S, Kaikimoto H, Matsumoto Y, Yamaguchi D, Kageyama-Yahara N, Fujishiro M, Wada R, Mitsushima T, Koike K
Gastric Cancer 2016 Jul;19(3):1016-22. Epub 2015 Oct 20 doi: 10.1007/s10120-015-0558-0. PMID: 26486508
Can the radiologist recognize Helicobacter pylori gastritis?
Mond DJ, Pochaczevsky R, Vernace F, Bank S, Chow KW
J Clin Gastroenterol 1995 Apr;20(3):199-202. doi: 10.1097/00004836-199504000-00007. PMID: 7797826
Enlarged gastric folds in association with Campylobacter pylori gastritis.
Morrison S, Dahms BB, Hoffenberg E, Czinn SJ
Radiology 1989 Jun;171(3):819-21. doi: 10.1148/radiology.171.3.2717759. PMID: 2717759

Diagnosis

Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy.
Chatrangsun B, Aumpan N, Pornthisarn B, Chonprasertsuk S, Siramolpiwat S, Bhanthumkomol P, Nunanan P, Issariyakulkarn N, Mahachai V, Yamaoka Y, Vilaichone RK
BMC Gastroenterol 2024 Jan 26;24(1):46. doi: 10.1186/s12876-024-03132-y. PMID: 38273222Free PMC Article
Clinicopathological features and prognosis of developed gastric cancer based on the diagnosis of mucosal atrophy and enlarged folds of stomach by double-contrast upper gastrointestinal barium X-ray radiography.
Yamamichi N, Shimamoto T, Hirano C, Takahashi Y, Minatsuki C, Takeuchi C, Takahashi M, Sakaguchi Y, Tsuji Y, Niimi K, Wada R, Mitsushima T, Koike K
Clin J Gastroenterol 2021 Aug;14(4):947-954. Epub 2021 May 20 doi: 10.1007/s12328-021-01445-z. PMID: 34018155
Ménétrier's disease : a case of successful treatment using long-acting octreotide.
Nunes G, Barosa R, Patita M, Pinto-Marques P, Gonçalves D, Fonseca C, Alves de Matos A, Fonseca J
Acta Gastroenterol Belg 2019 Jul-Sep;82(3):429-432. PMID: 31566332
Atrophic gastritis and enlarged gastric folds diagnosed by double-contrast upper gastrointestinal barium X-ray radiography are useful to predict future gastric cancer development based on the 3-year prospective observation.
Yamamichi N, Hirano C, Ichinose M, Takahashi Y, Minatsuki C, Matsuda R, Nakayama C, Shimamoto T, Kodashima S, Ono S, Tsuji Y, Niimi K, Sakaguchi Y, Kataoka Y, Saito I, Asada-Hirayama I, Takeuchi C, Yakabi S, Kaikimoto H, Matsumoto Y, Yamaguchi D, Kageyama-Yahara N, Fujishiro M, Wada R, Mitsushima T, Koike K
Gastric Cancer 2016 Jul;19(3):1016-22. Epub 2015 Oct 20 doi: 10.1007/s10120-015-0558-0. PMID: 26486508
The edematous toddler: a case of pediatric Ménétrier disease.
Blackstone MM, Mittal MK
Pediatr Emerg Care 2008 Oct;24(10):682-4. doi: 10.1097/PEC.0b013e3181887e89. PMID: 19240670

Therapy

Ménétrier's disease : a case of successful treatment using long-acting octreotide.
Nunes G, Barosa R, Patita M, Pinto-Marques P, Gonçalves D, Fonseca C, Alves de Matos A, Fonseca J
Acta Gastroenterol Belg 2019 Jul-Sep;82(3):429-432. PMID: 31566332
A pediatric non-protein losing Menetrier's disease successfully treated with octreotide long acting release.
Di Nardo G, Oliva S, Aloi M, Ferrari F, Frediani S, Marcheggiano A, Cucchiara S
World J Gastroenterol 2012 Jun 7;18(21):2727-9. doi: 10.3748/wjg.v18.i21.2727. PMID: 22690084Free PMC Article
The edematous toddler: a case of pediatric Ménétrier disease.
Blackstone MM, Mittal MK
Pediatr Emerg Care 2008 Oct;24(10):682-4. doi: 10.1097/PEC.0b013e3181887e89. PMID: 19240670
Ménétrièr's disease associated with Helicobacter pylori infection: resolution of enlarged gastric folds and hypoproteinemia after antibacterial treatment.
Kawasaki M, Hizawa K, Aoyagi K, Nakamura S, Fujishima M
Am J Gastroenterol 1997 Oct;92(10):1909-12. PMID: 9382064

Prognosis

Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy.
Chatrangsun B, Aumpan N, Pornthisarn B, Chonprasertsuk S, Siramolpiwat S, Bhanthumkomol P, Nunanan P, Issariyakulkarn N, Mahachai V, Yamaoka Y, Vilaichone RK
BMC Gastroenterol 2024 Jan 26;24(1):46. doi: 10.1186/s12876-024-03132-y. PMID: 38273222Free PMC Article
Clinicopathological features and prognosis of developed gastric cancer based on the diagnosis of mucosal atrophy and enlarged folds of stomach by double-contrast upper gastrointestinal barium X-ray radiography.
Yamamichi N, Shimamoto T, Hirano C, Takahashi Y, Minatsuki C, Takeuchi C, Takahashi M, Sakaguchi Y, Tsuji Y, Niimi K, Wada R, Mitsushima T, Koike K
Clin J Gastroenterol 2021 Aug;14(4):947-954. Epub 2021 May 20 doi: 10.1007/s12328-021-01445-z. PMID: 34018155
Atrophic gastritis and enlarged gastric folds diagnosed by double-contrast upper gastrointestinal barium X-ray radiography are useful to predict future gastric cancer development based on the 3-year prospective observation.
Yamamichi N, Hirano C, Ichinose M, Takahashi Y, Minatsuki C, Matsuda R, Nakayama C, Shimamoto T, Kodashima S, Ono S, Tsuji Y, Niimi K, Sakaguchi Y, Kataoka Y, Saito I, Asada-Hirayama I, Takeuchi C, Yakabi S, Kaikimoto H, Matsumoto Y, Yamaguchi D, Kageyama-Yahara N, Fujishiro M, Wada R, Mitsushima T, Koike K
Gastric Cancer 2016 Jul;19(3):1016-22. Epub 2015 Oct 20 doi: 10.1007/s10120-015-0558-0. PMID: 26486508
The edematous toddler: a case of pediatric Ménétrier disease.
Blackstone MM, Mittal MK
Pediatr Emerg Care 2008 Oct;24(10):682-4. doi: 10.1097/PEC.0b013e3181887e89. PMID: 19240670
Hyperplastic gastropathy. Clinicopathologic correlation.
Komorowski RA, Caya JG
Am J Surg Pathol 1991 Jun;15(6):577-85. doi: 10.1097/00000478-199106000-00006. PMID: 2031530

Clinical prediction guides

Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy.
Chatrangsun B, Aumpan N, Pornthisarn B, Chonprasertsuk S, Siramolpiwat S, Bhanthumkomol P, Nunanan P, Issariyakulkarn N, Mahachai V, Yamaoka Y, Vilaichone RK
BMC Gastroenterol 2024 Jan 26;24(1):46. doi: 10.1186/s12876-024-03132-y. PMID: 38273222Free PMC Article
Clinicopathological features and prognosis of developed gastric cancer based on the diagnosis of mucosal atrophy and enlarged folds of stomach by double-contrast upper gastrointestinal barium X-ray radiography.
Yamamichi N, Shimamoto T, Hirano C, Takahashi Y, Minatsuki C, Takeuchi C, Takahashi M, Sakaguchi Y, Tsuji Y, Niimi K, Wada R, Mitsushima T, Koike K
Clin J Gastroenterol 2021 Aug;14(4):947-954. Epub 2021 May 20 doi: 10.1007/s12328-021-01445-z. PMID: 34018155
Ménétrier's disease : a case of successful treatment using long-acting octreotide.
Nunes G, Barosa R, Patita M, Pinto-Marques P, Gonçalves D, Fonseca C, Alves de Matos A, Fonseca J
Acta Gastroenterol Belg 2019 Jul-Sep;82(3):429-432. PMID: 31566332
Atrophic gastritis and enlarged gastric folds diagnosed by double-contrast upper gastrointestinal barium X-ray radiography are useful to predict future gastric cancer development based on the 3-year prospective observation.
Yamamichi N, Hirano C, Ichinose M, Takahashi Y, Minatsuki C, Matsuda R, Nakayama C, Shimamoto T, Kodashima S, Ono S, Tsuji Y, Niimi K, Sakaguchi Y, Kataoka Y, Saito I, Asada-Hirayama I, Takeuchi C, Yakabi S, Kaikimoto H, Matsumoto Y, Yamaguchi D, Kageyama-Yahara N, Fujishiro M, Wada R, Mitsushima T, Koike K
Gastric Cancer 2016 Jul;19(3):1016-22. Epub 2015 Oct 20 doi: 10.1007/s10120-015-0558-0. PMID: 26486508
Possible role of transforming growth factor alpha in the pathogenesis of Ménétrier's disease: supportive evidence form humans and transgenic mice.
Dempsey PJ, Goldenring JR, Soroka CJ, Modlin IM, McClure RW, Lind CD, Ahlquist DA, Pittelkow MR, Lee DC, Sandgren EP
Gastroenterology 1992 Dec;103(6):1950-63. doi: 10.1016/0016-5085(92)91455-d. PMID: 1451986

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