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Morphological abnormality of the gastrointestinal tract

MedGen UID:
866726
•Concept ID:
C4021073
•
Anatomical Abnormality
Synonyms: Abnormal shape of the digestive system; Morphological abnormality of the GI tract; Morphological anomaly of the digestive system
 
HPO: HP:0012718

Definition

Abnormal structure of the gastrointestinal tract. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMorphological abnormality of the gastrointestinal tract

Professional guidelines

PubMed

The role of histopathology in the diagnosis and management of coeliac disease and other malabsorptive conditions.
Brown I, Bettington M, Rosty C
Histopathology 2021 Jan;78(1):88-105. doi: 10.1111/his.14262. PMID: 33382496
Diabetic gastroparesis: functional/morphologic background, diagnosis, and treatment options.
Horváth VJ, Izbéki F, Lengyel C, Kempler P, Várkonyi T
Curr Diab Rep 2014;14(9):527. doi: 10.1007/s11892-014-0527-8. PMID: 25005121
Clinical guidelines for imaging and reporting ingested foreign bodies.
Guelfguat M, Kaplinskiy V, Reddy SH, DiPoce J
AJR Am J Roentgenol 2014 Jul;203(1):37-53. doi: 10.2214/AJR.13.12185. PMID: 24951194

Recent clinical studies

Etiology

T- and NK-cell lymphoproliferative disorders of the gastrointestinal tract: review and update.
van Vliet C, Spagnolo DV
Pathology 2020 Jan;52(1):128-141. Epub 2019 Nov 11 doi: 10.1016/j.pathol.2019.10.001. PMID: 31727264
Down syndrome as a cause of abnormalities in the craniofacial region: A systematic literature review.
Kaczorowska N, Kaczorowski K, Laskowska J, Mikulewicz M
Adv Clin Exp Med 2019 Nov;28(11):1587-1592. doi: 10.17219/acem/112785. PMID: 31778604
Fetal megacystis: a lot more than LUTO.
Fontanella F, Maggio L, Verheij JBGM, Duin LK, Adama Van Scheltema PN, Cohen-Overbeek TE, Pajkrt E, Bekker M, Willekes C, Bax CJ, Gracchi V, Oepkes D, Bilardo CM
Ultrasound Obstet Gynecol 2019 Jun;53(6):779-787. doi: 10.1002/uog.19182. PMID: 30043466Free PMC Article
New therapies for vascular anomalies of the gastrointestinal tract.
Fox VL
Minerva Pediatr 2018 Jun;70(3):303-307. Epub 2018 Feb 23 doi: 10.23736/S0026-4946.18.05207-6. PMID: 29479946
Effect of alcohol consumption on the gut.
Bode C, Bode JC
Best Pract Res Clin Gastroenterol 2003 Aug;17(4):575-92. doi: 10.1016/s1521-6918(03)00034-9. PMID: 12828956

Diagnosis

T- and NK-cell lymphoproliferative disorders of the gastrointestinal tract: review and update.
van Vliet C, Spagnolo DV
Pathology 2020 Jan;52(1):128-141. Epub 2019 Nov 11 doi: 10.1016/j.pathol.2019.10.001. PMID: 31727264
Down syndrome as a cause of abnormalities in the craniofacial region: A systematic literature review.
Kaczorowska N, Kaczorowski K, Laskowska J, Mikulewicz M
Adv Clin Exp Med 2019 Nov;28(11):1587-1592. doi: 10.17219/acem/112785. PMID: 31778604
Fetal megacystis: a lot more than LUTO.
Fontanella F, Maggio L, Verheij JBGM, Duin LK, Adama Van Scheltema PN, Cohen-Overbeek TE, Pajkrt E, Bekker M, Willekes C, Bax CJ, Gracchi V, Oepkes D, Bilardo CM
Ultrasound Obstet Gynecol 2019 Jun;53(6):779-787. doi: 10.1002/uog.19182. PMID: 30043466Free PMC Article
Confocal endomicroscopy.
Dunbar K, Canto M
Curr Opin Gastroenterol 2008 Sep;24(5):631-7. doi: 10.1097/MOG.0b013e32830c91c7. PMID: 19122507
Defecography.
Yang XM, Partanen K, Farin P, Soimakallio S
Acta Radiol 1995 Sep;36(5):460-8. PMID: 7640087

Therapy

Encapsulating Peritoneal Sclerosis: The Abdominal Cocoon.
Singhal M, Krishna S, Lal A, Narayanasamy S, Bal A, Yadav TD, Kochhar R, Sinha SK, Khandelwal N, Sheikh AM
Radiographics 2019 Jan-Feb;39(1):62-77. Epub 2018 Dec 7 doi: 10.1148/rg.2019180108. PMID: 30526331
MR imaging of the small bowel.
Masselli G, Gualdi G
Radiology 2012 Aug;264(2):333-48. doi: 10.1148/radiol.12111658. PMID: 22821694
Effect of alcohol consumption on the gut.
Bode C, Bode JC
Best Pract Res Clin Gastroenterol 2003 Aug;17(4):575-92. doi: 10.1016/s1521-6918(03)00034-9. PMID: 12828956
Gut ischaemia.
Haglund U
Gut 1994 Jan;35(1 Suppl):S73-6. doi: 10.1136/gut.35.1_suppl.s73. PMID: 8125397Free PMC Article
The effects of steroids upon the gastrointestinal tract.
Black HE
Toxicol Pathol 1988;16(2):213-22. doi: 10.1177/019262338801600214. PMID: 3055231

Prognosis

Update on the Classification of and Diagnostic Approaches to Mature T-Cell Lymphomas.
Zhang X, Zhou J, Han X, Wang E, Zhang L
Arch Pathol Lab Med 2022 Aug 1;146(8):947-952. doi: 10.5858/arpa.2021-0143-RA. PMID: 34524423
T- and NK-cell lymphoproliferative disorders of the gastrointestinal tract: review and update.
van Vliet C, Spagnolo DV
Pathology 2020 Jan;52(1):128-141. Epub 2019 Nov 11 doi: 10.1016/j.pathol.2019.10.001. PMID: 31727264
Down syndrome as a cause of abnormalities in the craniofacial region: A systematic literature review.
Kaczorowska N, Kaczorowski K, Laskowska J, Mikulewicz M
Adv Clin Exp Med 2019 Nov;28(11):1587-1592. doi: 10.17219/acem/112785. PMID: 31778604
Encapsulating Peritoneal Sclerosis: The Abdominal Cocoon.
Singhal M, Krishna S, Lal A, Narayanasamy S, Bal A, Yadav TD, Kochhar R, Sinha SK, Khandelwal N, Sheikh AM
Radiographics 2019 Jan-Feb;39(1):62-77. Epub 2018 Dec 7 doi: 10.1148/rg.2019180108. PMID: 30526331
Gastric dysplasia.
Sipponen P
Curr Top Pathol 1990;81:61-76. doi: 10.1007/978-3-642-74662-8_3. PMID: 2407446

Clinical prediction guides

What Are the Characteristics of the Upper Airway in Patients With Craniofacial Microsomia?
Klazen YP, Caron CJJM, Schaal SC, Borghi A, Van der Schroeff MP, Dunaway DJ, Padwa BL, Koudstaal MJ
J Oral Maxillofac Surg 2019 Sep;77(9):1869-1881. Epub 2019 Mar 26 doi: 10.1016/j.joms.2019.03.017. PMID: 31002786
Denonvilliers' fascia revisited.
Kim JH, Kinugasa Y, Hwang SE, Murakami G, Rodríguez-Vázquez JF, Cho BH
Surg Radiol Anat 2015 Mar;37(2):187-97. Epub 2014 Jul 10 doi: 10.1007/s00276-014-1336-0. PMID: 25008480
Defecography.
Yang XM, Partanen K, Farin P, Soimakallio S
Acta Radiol 1995 Sep;36(5):460-8. PMID: 7640087
Gastric dysplasia.
Sipponen P
Curr Top Pathol 1990;81:61-76. doi: 10.1007/978-3-642-74662-8_3. PMID: 2407446
The effects of steroids upon the gastrointestinal tract.
Black HE
Toxicol Pathol 1988;16(2):213-22. doi: 10.1177/019262338801600214. PMID: 3055231

Recent systematic reviews

Down syndrome as a cause of abnormalities in the craniofacial region: A systematic literature review.
Kaczorowska N, Kaczorowski K, Laskowska J, Mikulewicz M
Adv Clin Exp Med 2019 Nov;28(11):1587-1592. doi: 10.17219/acem/112785. PMID: 31778604
Mucosal RNA and protein expression as the next frontier in IBS: abnormal function despite morphologically intact small intestinal mucosa.
Rodiño-Janeiro BK, Pardo-Camacho C, Santos J, Martínez C
Am J Physiol Gastrointest Liver Physiol 2019 Jun 1;316(6):G701-G719. Epub 2019 Feb 15 doi: 10.1152/ajpgi.00186.2018. PMID: 30767681

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