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Dyshidrosis

MedGen UID:
10851
•Concept ID:
C0032633
•
Disease or Syndrome
Synonyms: Dyshidrotic Eczema; Dyshidrotic Eczemas; Dyshydrotic Eczema; Dyshydrotic Eczemas; Eczema, Dyshidrotic; Eczema, Dyshydrotic; Eczema, Vesicular Palmoplantar; Eczemas, Dyshidrotic; Eczemas, Dyshydrotic; Eczemas, Vesicular Palmoplantar; Palmoplantar Eczema, Vesicular; Palmoplantar Eczemas, Vesicular; Pompholyx; Vesicular Palmoplantar Eczema; Vesicular Palmoplantar Eczemas
 
Monarch Initiative: MONDO:0006540

Definition

A recurrent eczematous reaction characterized by the development of vesicular eruptions on the palms and soles, particularly along the sides and between the digits. It is accompanied by pruritus, a burning sensation, and hyperhidrosis. The disease is self-limiting, lasting only a few weeks. (Dorland, 27th ed) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDyshidrosis

Professional guidelines

PubMed

Effectiveness and safety of dupilumab in the treatment of atopic dermatitis in children (6-11 years): data from a French multicentre retrospective cohort in daily practice.
Lasek A, Bellon N, Mallet S, Puzenat E, Bursztejn AC, Abasq C, Mazereeuw-Hautier J, Chiaverini C, Hubiche T, Raison Peyron N, Du Thanh A, Barbarot S, Aubert H, Reguiai Z, Droitcourt C, Fievet C, Bellissen A, Bachelerie M, Nosbaum A, Leymarie A, Armingaud P, Masson Regnault M, Mahé E; Research Group of the Société Française de Dermatologie Pédiatrique (GR SFDP); Research Group of eczéma atopique (GREAT)
J Eur Acad Dermatol Venereol 2022 Dec;36(12):2423-2429. Epub 2022 Aug 4 doi: 10.1111/jdv.18450. PMID: 35854650
Scar Management in the Pediatric and Adolescent Populations.
Krakowski AC, Totri CR, Donelan MB, Shumaker PR
Pediatrics 2016 Feb;137(2):e20142065. Epub 2016 Jan 7 doi: 10.1542/peds.2014-2065. PMID: 26743819
Mycotic infections. Effective management of conditions involving the skin, hair, and nails.
Goldstein AO, Smith KM, Ives TJ, Goldstein B
Geriatrics 2000 May;55(5):40-2, 45-7, 51-2. PMID: 10826264

Recent clinical studies

Etiology

Dyshidrosis is a risk factor for herpes zoster.
Hsu CY, Wang YC, Kao CH
J Eur Acad Dermatol Venereol 2015 Nov;29(11):2177-83. Epub 2015 Apr 27 doi: 10.1111/jdv.13175. PMID: 25917643
Corynebacterium-associated skin infections.
Blaise G, Nikkels AF, Hermanns-Lê T, Nikkels-Tassoudji N, Piérard GE
Int J Dermatol 2008 Sep;47(9):884-90. doi: 10.1111/j.1365-4632.2008.03773.x. PMID: 18937649
Dyshidrosis: epidemiology, clinical characteristics, and therapy.
Lofgren SM, Warshaw EM
Dermatitis 2006 Dec;17(4):165-81. doi: 10.2310/6620.2006.05021. PMID: 17150166
Cutaneous diseases in Asians.
Lee CS, Lim HW
Dermatol Clin 2003 Oct;21(4):669-77. doi: 10.1016/s0733-8635(03)00078-0. PMID: 14717407
Focal (segmental) dyshidrosis in syringomyelia.
Sudo K, Fujiki N, Tsuji S, Ajiki M, Higashi T, Niino M, Kikuchi S, Moriwaka F, Tashiro K
J Neurol Neurosurg Psychiatry 1999 Jul;67(1):106-8. doi: 10.1136/jnnp.67.1.106. PMID: 10369833Free PMC Article

Diagnosis

Dyshidrosiform Bullous Pemphigoid.
Cohen PR
Medicina (Kaunas) 2021 Apr 20;57(4) doi: 10.3390/medicina57040398. PMID: 33924249Free PMC Article
Dyshidrosis is a risk factor for herpes zoster.
Hsu CY, Wang YC, Kao CH
J Eur Acad Dermatol Venereol 2015 Nov;29(11):2177-83. Epub 2015 Apr 27 doi: 10.1111/jdv.13175. PMID: 25917643
Dyshidrosis.
Colomb-Lippa D, Klingler AM
JAAPA 2011 Jul;24(7):54. PMID: 21748961
Corynebacterium-associated skin infections.
Blaise G, Nikkels AF, Hermanns-Lê T, Nikkels-Tassoudji N, Piérard GE
Int J Dermatol 2008 Sep;47(9):884-90. doi: 10.1111/j.1365-4632.2008.03773.x. PMID: 18937649
Dyshidrosis: epidemiology, clinical characteristics, and therapy.
Lofgren SM, Warshaw EM
Dermatitis 2006 Dec;17(4):165-81. doi: 10.2310/6620.2006.05021. PMID: 17150166

Therapy

Dyshidrosiform Bullous Pemphigoid.
Cohen PR
Medicina (Kaunas) 2021 Apr 20;57(4) doi: 10.3390/medicina57040398. PMID: 33924249Free PMC Article
Scar Management in the Pediatric and Adolescent Populations.
Krakowski AC, Totri CR, Donelan MB, Shumaker PR
Pediatrics 2016 Feb;137(2):e20142065. Epub 2016 Jan 7 doi: 10.1542/peds.2014-2065. PMID: 26743819
Dyshidrosis is a risk factor for herpes zoster.
Hsu CY, Wang YC, Kao CH
J Eur Acad Dermatol Venereol 2015 Nov;29(11):2177-83. Epub 2015 Apr 27 doi: 10.1111/jdv.13175. PMID: 25917643
Corynebacterium-associated skin infections.
Blaise G, Nikkels AF, Hermanns-Lê T, Nikkels-Tassoudji N, Piérard GE
Int J Dermatol 2008 Sep;47(9):884-90. doi: 10.1111/j.1365-4632.2008.03773.x. PMID: 18937649
Dyshidrosis.
Plotnick H
Cutis 1977 Sep;20(3):373-5. PMID: 891254

Prognosis

Mycosis fungoides palmaris and plantaris.
André R
Ital J Dermatol Venerol 2024 Feb;159(1):1-3. Epub 2023 Nov 28 doi: 10.23736/S2784-8671.23.07645-4. PMID: 38015570
Detailed Analysis of Neurological Symptoms and Sensory Disturbances Due to Chronic Arsenic Exposure in Toroku, Japan.
Sugiyama T, Ishii N, Ebihara Y, Shiomi K, Mochizuki H
Int J Environ Res Public Health 2021 Oct 13;18(20) doi: 10.3390/ijerph182010749. PMID: 34682489Free PMC Article
Dyshidrosis is a risk factor for herpes zoster.
Hsu CY, Wang YC, Kao CH
J Eur Acad Dermatol Venereol 2015 Nov;29(11):2177-83. Epub 2015 Apr 27 doi: 10.1111/jdv.13175. PMID: 25917643
Corynebacterium-associated skin infections.
Blaise G, Nikkels AF, Hermanns-Lê T, Nikkels-Tassoudji N, Piérard GE
Int J Dermatol 2008 Sep;47(9):884-90. doi: 10.1111/j.1365-4632.2008.03773.x. PMID: 18937649
Cutaneous diseases in Asians.
Lee CS, Lim HW
Dermatol Clin 2003 Oct;21(4):669-77. doi: 10.1016/s0733-8635(03)00078-0. PMID: 14717407

Clinical prediction guides

Intravenous and subcutaneous immunoglobulins-associated eczematous reactions occur with a broad range of immunoglobulin types: A French national multicenter study.
Voland P, Barthel C, Azzouz B, Raison-Peyron N, Du-Thanh A, Staumont-Sallé D, Jachiet M, Soria A, Nosbaum A, Valois A, Leleu C, Lebrun-Vignes B, Trenque T, Hettler D, Bernier C, Viguier M; French Group of Research and Study in Atopic Eczema (GREAT) of the French Society of Dermatology
J Am Acad Dermatol 2023 Feb;88(2):380-387. Epub 2022 Oct 15 doi: 10.1016/j.jaad.2022.10.015. PMID: 36252685
Dyshidrosiform Bullous Pemphigoid.
Cohen PR
Medicina (Kaunas) 2021 Apr 20;57(4) doi: 10.3390/medicina57040398. PMID: 33924249Free PMC Article
Multidimensional analysis of clinical symptoms in patients with Fabry's disease.
Kaminsky P, Noel E, Jaussaud R, Leguy-Seguin V, Hachulla E, Zenone T, Lavigne C, Marie I, Maillot F, Masseau A, Serratrice C, Lidove O
Int J Clin Pract 2013 Feb;67(2):120-7. doi: 10.1111/ijcp.12016. PMID: 23305474
Focal (segmental) dyshidrosis in syringomyelia.
Sudo K, Fujiki N, Tsuji S, Ajiki M, Higashi T, Niino M, Kikuchi S, Moriwaka F, Tashiro K
J Neurol Neurosurg Psychiatry 1999 Jul;67(1):106-8. doi: 10.1136/jnnp.67.1.106. PMID: 10369833Free PMC Article
Epidemiological, clinical and allergological observations on pompholyx.
Lodi A, Betti R, Chiarelli G, Urbani CE, Crosti C
Contact Dermatitis 1992 Jan;26(1):17-21. doi: 10.1111/j.1600-0536.1992.tb00862.x. PMID: 1534730

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