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Rectal polyposis

MedGen UID:
11150
•Concept ID:
C0034887
•
Neoplastic Process
Synonyms: Multiple rectal polyps; Polyp of rectum; Polyp of Rectum; polyp of rectum; Polyp of the Rectum; polyp of the rectum; Rectal polyp; Rectal Polyp; rectal polyp; Rectal polyps; rectum polyp
SNOMED CT: Polyp of rectum (39772007); Rectal polyp (39772007)
 
HPO: HP:0100896
Monarch Initiative: MONDO:0021398

Definition

The presence of multiple rectal hyperplastic/adenomatous polyps. [from HPO]

Professional guidelines

PubMed

Endoscopic and chemopreventive management of familial adenomatous polyposis syndrome.
Stone JK, Mehta NA, Singh H, El-Matary W, Bernstein CN
Fam Cancer 2023 Oct;22(4):413-422. Epub 2023 Apr 29 doi: 10.1007/s10689-023-00334-3. PMID: 37119510
Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium.
Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B
Lancet Gastroenterol Hepatol 2022 Sep;7(9):871-893. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00039-5. PMID: 35798022
Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium.
Shen B, Kochhar GS, Kariv R, Liu X, Navaneethan U, Rubin DT, Cross RK, Sugita A, D'Hoore A, Schairer J, Farraye FA, Kiran RP, Fleshner P, Rosh J, Shah SA, Chang S, Scherl E, Pardi DS, Schwartz DA, Kotze PG, Bruining DH, Kane SV, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, McCormick JT, Picoraro JA, Silverberg MS, Bernstein CN, Sandborn WJ, Vermeire S
Lancet Gastroenterol Hepatol 2021 Oct;6(10):826-849. Epub 2021 Aug 18 doi: 10.1016/S2468-1253(21)00101-1. PMID: 34416186

Recent clinical studies

Etiology

Risk of cancer and secondary proctectomy after colectomy and ileorectal anastomosis in familial adenomatous polyposis.
Koskenvuo L, Renkonen-Sinisalo L, Järvinen HJ, Lepistö A
Int J Colorectal Dis 2014 Feb;29(2):225-30. Epub 2013 Nov 30 doi: 10.1007/s00384-013-1796-4. PMID: 24292488
Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis.
Nascimbeni R, Pucciarelli S, Di Lorenzo D, Urso E, Casella C, Agostini M, Nitti D, Salerni B
Dis Colon Rectum 2010 Dec;53(12):1670-5. doi: 10.1007/DCR.0b013e3181ee3d6b. PMID: 21178863
Balance between endoscopic and genetic information in the choice of ileorectal anastomosis for familial adenomatous polyposis.
Valanzano R, Ficari F, Curia MC, Aceto G, Veschi S, Cama A, Battista P, Tonelli F
J Surg Oncol 2007 Jan 1;95(1):28-33. doi: 10.1002/jso.20672. PMID: 17192888
Restorative proctocolectomy or rectum-preserving surgery in patients with familial adenomatous polyposis: results of a prospective study.
Tonelli F, Valanzano R, Monaci I, Mazzoni P, Anastasi A, Ficari F
World J Surg 1997 Jul-Aug;21(6):653-8; discussion 659. doi: 10.1007/s002689900289. PMID: 9230666
Familial polyposis of the colon with special reference to regression of rectal polyposis after subtotal colectomy.
Shepherd A
Br J Surg 1971 Feb;58(2):85-91. doi: 10.1002/bjs.1800580202. PMID: 5548512

Diagnosis

Multistage Rectal Polypectomy: An Alternative to Proctectomy in Patients With Familial Adenomatous Polyposis.
Sommovilla J, Liska D, Church J
Dis Colon Rectum 2021 Jul 1;64(7):e391-e394. doi: 10.1097/DCR.0000000000002030. PMID: 33872285
Tuberous Sclerosis Complex with rare associated findings in the gastrointestinal system: a case report and review of the literature.
Reis LB, Konzen D, Netto CBO, Braghini PMB, Prolla G, Ashton-Prolla P
BMC Gastroenterol 2020 Nov 23;20(1):394. doi: 10.1186/s12876-020-01481-y. PMID: 33225890Free PMC Article
An unusual cause of rectal polyposis.
Köklü S, Guler G
Acta Gastroenterol Belg 2018 Jul-Sep;81(3):453. PMID: 30350544
Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis.
Nascimbeni R, Pucciarelli S, Di Lorenzo D, Urso E, Casella C, Agostini M, Nitti D, Salerni B
Dis Colon Rectum 2010 Dec;53(12):1670-5. doi: 10.1007/DCR.0b013e3181ee3d6b. PMID: 21178863
Mucosal prolapse syndrome presenting as rectal polyposis.
Brosens LA, Montgomery EA, Bhagavan BS, Offerhaus GJ, Giardiello FM
J Clin Pathol 2009 Nov;62(11):1034-6. doi: 10.1136/jcp.2009.067801. PMID: 19861563Free PMC Article

Therapy

Multistage Rectal Polypectomy: An Alternative to Proctectomy in Patients With Familial Adenomatous Polyposis.
Sommovilla J, Liska D, Church J
Dis Colon Rectum 2021 Jul 1;64(7):e391-e394. doi: 10.1097/DCR.0000000000002030. PMID: 33872285
Effect of indomethacin suppositories on rectal polyposis in patients with familial adenomatous polyposis.
Hirota C, Iida M, Aoyagi K, Matsumoto T, Tada S, Yao T, Fujishima M
Cancer 1996 Oct 15;78(8):1660-5. PMID: 8859177
Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis.
Nugent KP, Farmer KC, Spigelman AD, Williams CB, Phillips RK
Br J Surg 1993 Dec;80(12):1618-9. doi: 10.1002/bjs.1800801244. PMID: 8298943
Local chemotherapy for rectal polyposis: intraluminal administration of 5-fluorouracil for postoperative control of adenomas in the retained rectum in familial polyposis.
Itoh H, Iida M, Mibu R, Terasaka R, Ohsato K
J Clin Gastroenterol 1989 Dec;11(6):645-9. PMID: 2555408

Prognosis

Balance between endoscopic and genetic information in the choice of ileorectal anastomosis for familial adenomatous polyposis.
Valanzano R, Ficari F, Curia MC, Aceto G, Veschi S, Cama A, Battista P, Tonelli F
J Surg Oncol 2007 Jan 1;95(1):28-33. doi: 10.1002/jso.20672. PMID: 17192888
Rectal polyposis as a guide to duodenal polyposis in familial adenomatous polyposis.
Spigelman AD, Williams CB, Phillips RK
J R Soc Med 1992 Feb;85(2):77-9. doi: 10.1177/014107689208500208. PMID: 1311384Free PMC Article
Familial polyposis of the colon with special reference to regression of rectal polyposis after subtotal colectomy.
Shepherd A
Br J Surg 1971 Feb;58(2):85-91. doi: 10.1002/bjs.1800580202. PMID: 5548512

Clinical prediction guides

Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis.
Nascimbeni R, Pucciarelli S, Di Lorenzo D, Urso E, Casella C, Agostini M, Nitti D, Salerni B
Dis Colon Rectum 2010 Dec;53(12):1670-5. doi: 10.1007/DCR.0b013e3181ee3d6b. PMID: 21178863
Balance between endoscopic and genetic information in the choice of ileorectal anastomosis for familial adenomatous polyposis.
Valanzano R, Ficari F, Curia MC, Aceto G, Veschi S, Cama A, Battista P, Tonelli F
J Surg Oncol 2007 Jan 1;95(1):28-33. doi: 10.1002/jso.20672. PMID: 17192888
Restorative proctocolectomy or rectum-preserving surgery in patients with familial adenomatous polyposis: results of a prospective study.
Tonelli F, Valanzano R, Monaci I, Mazzoni P, Anastasi A, Ficari F
World J Surg 1997 Jul-Aug;21(6):653-8; discussion 659. doi: 10.1007/s002689900289. PMID: 9230666
Effect of indomethacin suppositories on rectal polyposis in patients with familial adenomatous polyposis.
Hirota C, Iida M, Aoyagi K, Matsumoto T, Tada S, Yao T, Fujishima M
Cancer 1996 Oct 15;78(8):1660-5. PMID: 8859177
Rectal polyposis as a guide to duodenal polyposis in familial adenomatous polyposis.
Spigelman AD, Williams CB, Phillips RK
J R Soc Med 1992 Feb;85(2):77-9. doi: 10.1177/014107689208500208. PMID: 1311384Free PMC Article

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