U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Thrombophlebitis

MedGen UID:
11799
Concept ID:
C0040046
Pathologic Function
Synonym: Thrombophlebitides
SNOMED CT: Thrombophlebitis (64156001)
 
HPO: HP:0004418
Monarch Initiative: MONDO:0002800

Definition

Inflammation of a vein associated with venous thrombosis (blood clot formation within the vein). [from HPO]

Conditions with this feature

Combined oxidative phosphorylation deficiency 54
MedGen UID:
1812715
Concept ID:
C5676912
Disease or Syndrome
Combined oxidative phosphorylation deficiency-54 (COXPD54) is an autosomal recessive disorder with pleiotropic multisystem presentations resulting from a disruption in mitochondrial transcription and translation. The phenotype is highly variable. Many patients have early-onset sensorineural hearing loss, sometimes in isolation, and sometimes associated with global developmental delay or primary ovarian failure. Other features may include peripheral hypertonia, seizures, muscle weakness, behavioral abnormalities, and leukoencephalopathy on brain imaging. Serum lactate may or may not be elevated (summary by Hochberg et al., 2021). For a discussion of genetic heterogeneity of combined oxidative phosphorylation deficiency, see COXPD1 (609060).

Professional guidelines

PubMed

Gloviczki P, Lawrence PF, Wasan SM, Meissner MH, Almeida J, Brown KR, Bush RL, Di Iorio M, Fish J, Fukaya E, Gloviczki ML, Hingorani A, Jayaraj A, Kolluri R, Murad MH, Obi AT, Ozsvath KJ, Singh MJ, Vayuvegula S, Welch HJ
J Vasc Surg Venous Lymphat Disord 2024 Jan;12(1):101670. Epub 2023 Aug 29 doi: 10.1016/j.jvsv.2023.08.011. PMID: 37652254Free PMC Article
Buetti N, Timsit JF
Semin Respir Crit Care Med 2019 Aug;40(4):508-523. Epub 2019 Oct 4 doi: 10.1055/s-0039-1693705. PMID: 31585477
Chaves F, Garnacho-Montero J, Del Pozo JL, Bouza E, Capdevila JA, de Cueto M, Domínguez MÁ, Esteban J, Fernández-Hidalgo N, Fernández Sampedro M, Fortún J, Guembe M, Lorente L, Paño JR, Ramírez P, Salavert M, Sánchez M, Vallés J
Med Intensiva (Engl Ed) 2018 Jan-Feb;42(1):5-36. doi: 10.1016/j.medin.2017.09.012. PMID: 29406956

Recent clinical studies

Etiology

Saxonhouse MA, Hinson A
Curr Pediatr Rev 2023;19(4):366-370. doi: 10.2174/1573396319666221124121815. PMID: 36424785
Amano M, Shimizu T
Intern Med 2018 Sep 15;57(18):2607-2612. Epub 2018 May 18 doi: 10.2169/internalmedicine.0495-17. PMID: 29780120Free PMC Article
Lee JT, Kalani MA
J Natl Compr Canc Netw 2008 Sep;6(8):760-5. doi: 10.6004/jnccn.2008.0057. PMID: 18926088
Collins LM
Nurse Pract Forum 1998 Sep;9(3):163-9. PMID: 9782900
Hessov I
Acta Anaesthesiol Scand Suppl 1985;82:33-7. doi: 10.1111/j.1399-6576.1985.tb02339.x. PMID: 3904298

Diagnosis

Saxonhouse MA, Hinson A
Curr Pediatr Rev 2023;19(4):366-370. doi: 10.2174/1573396319666221124121815. PMID: 36424785
Koushk-Jalali B, Tigges C, Kreuter A
Dtsch Arztebl Int 2020 Feb 21;116(8):125. doi: 10.3238/arztebl.2020.0125. PMID: 32181733Free PMC Article
Nordlie H, Tangerud Å, Thorsnes SE, Breivik S
Tidsskr Nor Laegeforen 2018 May 29;138(9) Epub 2018 May 18 doi: 10.4045/tidsskr.18.0091. PMID: 29808659
Luis Rodríguez-Peralto J, Carrillo R, Rosales B, Rodríguez-Gil Y
Semin Cutan Med Surg 2007 Jun;26(2):71-6. doi: 10.1016/j.sder.2007.02.002. PMID: 17544957
Kerstein MD
Angiology 1977 Apr;28(4):228-34. doi: 10.1177/000331977702800402. PMID: 326098

Therapy

Webster J, Osborne S, Rickard CM, Marsh N
Cochrane Database Syst Rev 2019 Jan 23;1(1):CD007798. doi: 10.1002/14651858.CD007798.pub5. PMID: 30671926Free PMC Article
Di Nisio M, Wichers IM, Middeldorp S
Cochrane Database Syst Rev 2018 Feb 25;2(2):CD004982. doi: 10.1002/14651858.CD004982.pub6. PMID: 29478266Free PMC Article
Di Nisio M, Wichers IM, Middeldorp S
Cochrane Database Syst Rev 2012 Mar 14;(3):CD004982. doi: 10.1002/14651858.CD004982.pub4. PMID: 22419302
Anderson AD, Palmer D, MacFie J
Br J Surg 2003 Sep;90(9):1048-54. doi: 10.1002/bjs.4328. PMID: 12945070
Townend J, O'Sullivan J, Wilde JT
Blood Rev 1998 Mar;12(1):23-34. doi: 10.1016/s0268-960x(98)90027-3. PMID: 9597195

Prognosis

Lv L, Zhang J
J Vasc Access 2020 May;21(3):342-349. Epub 2019 Sep 23 doi: 10.1177/1129729819877323. PMID: 31547791
Ladizinski B, Federman DG
CMAJ 2013 Sep 3;185(12):1063. Epub 2012 Nov 26 doi: 10.1503/cmaj.121344. PMID: 23184841Free PMC Article
Pugh CM, DeWitty RL
J Natl Med Assoc 1996 Jun;88(6):359-63. PMID: 8691496Free PMC Article
Donati MB
Haemostasis 1994 Mar-Apr;24(2):128-31. doi: 10.1159/000217092. PMID: 7959360
Rahr HB, Sørensen JV
Blood Coagul Fibrinolysis 1992 Aug;3(4):451-60. PMID: 1420820

Clinical prediction guides

Belramman A, Bootun R, Lane TRA, Davies AH
J Vasc Surg Venous Lymphat Disord 2024 Mar;12(2):101729. Epub 2023 Dec 9 doi: 10.1016/j.jvsv.2023.101729. PMID: 38081513Free PMC Article
Custer PL, Ho TC, Boulos F
Ophthalmic Plast Reconstr Surg 2023 Jan-Feb 01;39(1):58-63. Epub 2022 Jul 4 doi: 10.1097/IOP.0000000000002241. PMID: 35793665
Ito H, Ogawa Y, Shimojo N, Kawano S
Breast Dis 2022;41(1):273-278. doi: 10.3233/BD-210056. PMID: 35634842
Wang H, Guo Y, Yan B, Zhang Q, Pan T, Liu Z, Chang Z
Eur Radiol 2022 Sep;32(9):6397-6406. Epub 2022 Apr 2 doi: 10.1007/s00330-022-08740-4. PMID: 35364715
Lee AY, Ginsberg JS
Curr Opin Pulm Med 1997 Jul;3(4):275-9. doi: 10.1097/00063198-199707000-00007. PMID: 9262113

Recent systematic reviews

Gloviczki P, Lawrence PF, Wasan SM, Meissner MH, Almeida J, Brown KR, Bush RL, Di Iorio M, Fish J, Fukaya E, Gloviczki ML, Hingorani A, Jayaraj A, Kolluri R, Murad MH, Obi AT, Ozsvath KJ, Singh MJ, Vayuvegula S, Welch HJ
J Vasc Surg Venous Lymphat Disord 2024 Jan;12(1):101670. Epub 2023 Aug 29 doi: 10.1016/j.jvsv.2023.08.011. PMID: 37652254Free PMC Article
Marsh N, Webster J, Ullman AJ, Mihala G, Cooke M, Chopra V, Rickard CM
J Adv Nurs 2020 Dec;76(12):3346-3362. Epub 2020 Oct 5 doi: 10.1111/jan.14565. PMID: 33016412
Webster J, Osborne S, Rickard CM, Marsh N
Cochrane Database Syst Rev 2019 Jan 23;1(1):CD007798. doi: 10.1002/14651858.CD007798.pub5. PMID: 30671926Free PMC Article
Di Nisio M, Wichers IM, Middeldorp S
Cochrane Database Syst Rev 2018 Feb 25;2(2):CD004982. doi: 10.1002/14651858.CD004982.pub6. PMID: 29478266Free PMC Article
Gahr M, Freudenmann RW, Hiemke C, Gunst IM, Connemann BJ, Schönfeldt-Lecuona C
J Addict Dis 2012;31(4):407-12. doi: 10.1080/10550887.2012.735570. PMID: 23244560

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...