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Benign lymphoepithelial lesion of salivary gland

MedGen UID:
120595
Concept ID:
C0266995
Disease or Syndrome
Synonyms: Benign Lymphoepithelial Lesion of Salivary Gland; benign lymphoepithelial lesion of salivary gland; Benign Lymphoepithelial Lesion of the Salivary Gland; benign lymphoepithelial lesion of the salivary gland; Benign lymphoepithelial salivary gland lesion; Benign Salivary Gland Lymphoepithelial Lesion; benign salivary gland lymphoepithelial lesion; Godwin Tumor; Godwin tumor; Godwin tumour
SNOMED CT: Benign lymphoepithelial salivary gland lesion (45517002); Benign lymphoepithelial lesion of salivary gland (45517002)
 
Monarch Initiative: MONDO:0001598

Definition

A benign lesion that involves the salivary glands, usually the parotid gland. It affects females more often than males and it may be a manifestation of autoimmune diseases such as Sjogren syndrome. There is an increased incidence of benign lymphoepithelial lesions in HIV-positive patients. It is characterized by the presence of a marked lymphocytic infiltrate and epi-myoepithelial islands in the affected salivary gland. Patients usually present with firm and painless swelling of the affected salivary gland. There is an increased risk for development of lymphoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign lymphoepithelial lesion of salivary gland

Professional guidelines

PubMed

Ma Q, Song H
Rheumatol Int 2011 Jul;31(7):959-62. Epub 2010 Nov 11 doi: 10.1007/s00296-010-1617-9. PMID: 21069527

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