U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Klumpke-Déjerine paralysis

MedGen UID:
124376
•Concept ID:
C0270898
•
Disease or Syndrome
Synonyms: Dejerine-Klumpke palsy; Klumpke paralysis; Klumpke's palsy; Klumpke's paralysis; Lower brachial plexus palsy
SNOMED CT: Klumpke paralysis (83886009); Klumpke-Dejerine paralysis (83886009); Klumpke-Déjerine paralysis (83886009); Klumpke's paralysis (83886009); Klumpke's palsy (83886009); Klumpke-Déjerine brachial plexus injury (83886009)
 
Monarch Initiative: MONDO:0023054

Definition

Weakness or paralysis of muscles in the forearm or hand due to damage of the lower brachial plexus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVKlumpke-Déjerine paralysis

Professional guidelines

PubMed

Neonatal brachial plexus palsy - early diagnosis and treatment.
Berényi M, Szeredai M, Cseh Á
Ideggyogy Sz 2022 Jul 30;75(7-08):247-252. doi: 10.18071/isz.75.0247. PMID: 35916611
Evaluation and Management of Fetal Macrosomia.
Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Neuralgic amyotrophy: a paradigm shift in diagnosis and treatment.
Gstoettner C, Mayer JA, Rassam S, Hruby LA, Salminger S, Sturma A, Aman M, Harhaus L, Platzgummer H, Aszmann OC
J Neurol Neurosurg Psychiatry 2020 Aug;91(8):879-888. Epub 2020 Jun 2 doi: 10.1136/jnnp-2020-323164. PMID: 32487526

Recent clinical studies

Etiology

Anatomy, Imaging, and Pathologic Conditions of the Brachial Plexus.
Gilcrease-Garcia BM, Deshmukh SD, Parsons MS
Radiographics 2020 Oct;40(6):1686-1714. doi: 10.1148/rg.2020200012. PMID: 33001787
Evaluation of functional outcomes after brachial plexus injury.
Quick TJ, Brown H
J Hand Surg Eur Vol 2020 Jan;45(1):28-33. Epub 2019 Oct 9 doi: 10.1177/1753193419879645. PMID: 31597518
Brachial plexus injury after shoulder dislocation: a literature review.
Gutkowska O, Martynkiewicz J, Urban M, Gosk J
Neurosurg Rev 2020 Apr;43(2):407-423. Epub 2018 Jun 30 doi: 10.1007/s10143-018-1001-x. PMID: 29961154Free PMC Article
Obstetrical Brachial Plexus Palsy.
O'Berry P, Brown M, Phillips L, Evans SH
Curr Probl Pediatr Adolesc Health Care 2017 Jul;47(7):151-155. Epub 2017 Jul 12 doi: 10.1016/j.cppeds.2017.06.003. PMID: 28709767
Isolated lower brachial plexus (Klumpke) palsy with compound arm presentation: case report.
Buchanan EP, Richardson R, Tse R
J Hand Surg Am 2013 Aug;38(8):1567-70. Epub 2013 Jun 28 doi: 10.1016/j.jhsa.2013.04.021. PMID: 23810571

Diagnosis

Neonatal brachial plexus palsy - early diagnosis and treatment.
Berényi M, Szeredai M, Cseh Á
Ideggyogy Sz 2022 Jul 30;75(7-08):247-252. doi: 10.18071/isz.75.0247. PMID: 35916611
Anatomy, Imaging, and Pathologic Conditions of the Brachial Plexus.
Gilcrease-Garcia BM, Deshmukh SD, Parsons MS
Radiographics 2020 Oct;40(6):1686-1714. doi: 10.1148/rg.2020200012. PMID: 33001787
Adult Traumatic Brachial Plexus Injuries.
Noland SS, Bishop AT, Spinner RJ, Shin AY
J Am Acad Orthop Surg 2019 Oct 1;27(19):705-716. doi: 10.5435/JAAOS-D-18-00433. PMID: 30707114
Radiation-induced brachial plexus neuropathy: A review.
Warade AC, Jha AK, Pattankar S, Desai K
Neurol India 2019 Jan-Feb;67(Supplement):S47-S52. doi: 10.4103/0028-3886.250704. PMID: 30688233
Rehabilitation of brachial plexus injuries in adults and children.
Smania N, Berto G, La Marchina E, Melotti C, Midiri A, Roncari L, Zenorini A, Ianes P, Picelli A, Waldner A, Faccioli S, Gandolfi M
Eur J Phys Rehabil Med 2012 Sep;48(3):483-506. PMID: 23075907

Therapy

Neuralgic Amyotrophy.
Holle JF, Limmroth V, Windisch W, Zimmerman M
Dtsch Arztebl Int 2024 Jul 26;121(15):483-489. doi: 10.3238/arztebl.m2024.0077. PMID: 38835178Free PMC Article
Effect of virtual reality versus conventional physiotherapy on upper extremity function in children with obstetric brachial plexus injury.
El-Shamy S, Alsharif R
J Musculoskelet Neuronal Interact 2017 Dec 1;17(4):319-326. PMID: 29199193Free PMC Article
Neuralgic amyotrophy: An update on diagnosis, pathophysiology, and treatment.
Van Eijk JJ, Groothuis JT, Van Alfen N
Muscle Nerve 2016 Mar;53(3):337-50. Epub 2016 Jan 20 doi: 10.1002/mus.25008. PMID: 26662794
Complications of shoulder dystocia.
Dajani NK, Magann EF
Semin Perinatol 2014 Jun;38(4):201-4. doi: 10.1053/j.semperi.2014.04.005. PMID: 24863025
Neuralgic amyotrophy.
Aymond JK, Goldner JL, Hardaker WT Jr
Orthop Rev 1989 Dec;18(12):1275-9. PMID: 2687774

Prognosis

Anatomy, Imaging, and Pathologic Conditions of the Brachial Plexus.
Gilcrease-Garcia BM, Deshmukh SD, Parsons MS
Radiographics 2020 Oct;40(6):1686-1714. doi: 10.1148/rg.2020200012. PMID: 33001787
Planning Interventions to Treat Brachial Plexopathies.
Bunnell AE, Kao DS
Phys Med Rehabil Clin N Am 2018 Nov;29(4):689-700. Epub 2018 Sep 5 doi: 10.1016/j.pmr.2018.06.005. PMID: 30293624
Obstetrical Brachial Plexus Palsy.
O'Berry P, Brown M, Phillips L, Evans SH
Curr Probl Pediatr Adolesc Health Care 2017 Jul;47(7):151-155. Epub 2017 Jul 12 doi: 10.1016/j.cppeds.2017.06.003. PMID: 28709767
Isolated lower brachial plexus (Klumpke) palsy with compound arm presentation: case report.
Buchanan EP, Richardson R, Tse R
J Hand Surg Am 2013 Aug;38(8):1567-70. Epub 2013 Jun 28 doi: 10.1016/j.jhsa.2013.04.021. PMID: 23810571
Shoulder dystocia.
Grobman W
Obstet Gynecol Clin North Am 2013 Mar;40(1):59-67. doi: 10.1016/j.ogc.2012.11.006. PMID: 23466137

Clinical prediction guides

Brachial plexus injury after shoulder dislocation: a literature review.
Gutkowska O, Martynkiewicz J, Urban M, Gosk J
Neurosurg Rev 2020 Apr;43(2):407-423. Epub 2018 Jun 30 doi: 10.1007/s10143-018-1001-x. PMID: 29961154Free PMC Article
Planning Interventions to Treat Brachial Plexopathies.
Bunnell AE, Kao DS
Phys Med Rehabil Clin N Am 2018 Nov;29(4):689-700. Epub 2018 Sep 5 doi: 10.1016/j.pmr.2018.06.005. PMID: 30293624
Effect of virtual reality versus conventional physiotherapy on upper extremity function in children with obstetric brachial plexus injury.
El-Shamy S, Alsharif R
J Musculoskelet Neuronal Interact 2017 Dec 1;17(4):319-326. PMID: 29199193Free PMC Article
Update in electromyography.
Pitt M
Curr Opin Pediatr 2013 Dec;25(6):676-81. doi: 10.1097/MOP.0000000000000023. PMID: 24136299
Shoulder dystocia.
Grobman W
Obstet Gynecol Clin North Am 2013 Mar;40(1):59-67. doi: 10.1016/j.ogc.2012.11.006. PMID: 23466137

Recent systematic reviews

Thoracic outlet syndrome in females: A systematic review.
Cralle LE, Harris LM, Lum YW, Deery SE, Humphries MD
Semin Vasc Surg 2023 Dec;36(4):487-491. Epub 2023 Sep 23 doi: 10.1053/j.semvascsurg.2023.09.003. PMID: 38030322
Surgical timing in neonatal brachial plexus palsy: A PRISMA-IPD systematic review.
Srinivasan N, Mahajan J, Gupta S, Shah YM, Shafei J, Levidy MF, Abdelmalek G, Pant K, Jain K, Zhao C, Chu A, McGrath A
Microsurgery 2022 May;42(4):381-390. Epub 2022 Feb 11 doi: 10.1002/micr.30871. PMID: 35147253Free PMC Article
Upper extremity nerve transfers for acute flaccid myelitis: a systematic literature review.
Texakalidis P, Xenos D, Murthy NK, Karras CL, Trybula SJ, Behbahani M, DeCuypere MG, Lam SK, Alden TD
Childs Nerv Syst 2022 Mar;38(3):521-526. Epub 2022 Jan 4 doi: 10.1007/s00381-021-05419-x. PMID: 34982205
Modified constraint induced movement therapy in children with obstetric brachial plexus palsy: a systematic review.
Sicari M, Longhi M, D'Angelo G, Boetto V, Lavorato A, Cocchini L, Beatrici M, Battiston B, Garbossa D, Massazza G, Titolo P
Eur J Phys Rehabil Med 2022 Feb;58(1):43-50. Epub 2021 Nov 8 doi: 10.23736/S1973-9087.21.06886-6. PMID: 34747579Free PMC Article
C5 nerve root palsy after posterior cervical spine surgery.
Pan FM, Wang SJ, Ma B, Wu DS
J Orthop Surg (Hong Kong) 2017 Jan;25(1):2309499016684502. doi: 10.1177/2309499016684502. PMID: 28176604

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...