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Abnormal nervous system physiology

MedGen UID:
868417
•Concept ID:
C4022811
•
Pathologic Function
Synonym: Abnormality of nervous system physiology
 
HPO: HP:0012638

Definition

A functional anomaly of the nervous system. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Abnormal nervous system physiology

Professional guidelines

PubMed

Epidemiology, Staging, and Management of Multiple Myeloma.
Padala SA, Barsouk A, Barsouk A, Rawla P, Vakiti A, Kolhe R, Kota V, Ajebo GH
Med Sci (Basel) 2021 Jan 20;9(1) doi: 10.3390/medsci9010003. PMID: 33498356Free PMC Article
Chronic inflammatory demyelinating polyradiculoneuropathy-Diagnostic pitfalls and treatment approach.
Stino AM, Naddaf E, Dyck PJ, Dyck PJB
Muscle Nerve 2021 Feb;63(2):157-169. Epub 2020 Sep 11 doi: 10.1002/mus.27046. PMID: 32914902
Central post-stroke pain: clinical characteristics, pathophysiology, and management.
Klit H, Finnerup NB, Jensen TS
Lancet Neurol 2009 Sep;8(9):857-68. doi: 10.1016/S1474-4422(09)70176-0. PMID: 19679277

Recent clinical studies

Etiology

Team Approach: Hip Preservation Surgery.
Kuhn AW, Clohisy JC, Troyer SC, Cheng AL, Hillen TJ, Pascual-Garrido C, Tatman J, Bloom N, Schoenecker PL, Nepple JJ
JBJS Rev 2023 Oct 1;11(10) Epub 2023 Oct 4 doi: 10.2106/JBJS.RVW.23.00041. PMID: 37793005Free PMC Article
Positional Plagiocephaly and Craniosynostosis.
Santiago GS, Santiago CN, Chwa ES, Purnell CA
Pediatr Ann 2023 Jan;52(1):e10-e17. Epub 2023 Jan 1 doi: 10.3928/19382359-20221114-03. PMID: 36625797
Environmental and individual exposure and the risk of congenital anomalies: a review of recent epidemiological evidence.
Baldacci S, Gorini F, Santoro M, Pierini A, Minichilli F, Bianchi F
Epidemiol Prev 2018 May-Aug;42(3-4 Suppl 1):1-34. doi: 10.19191/EP18.3-4.S1.P001.057. PMID: 30066535
Nervous System Malformations.
Gaitanis J, Tarui T
Continuum (Minneap Minn) 2018 Feb;24(1, Child Neurology):72-95. doi: 10.1212/CON.0000000000000561. PMID: 29432238Free PMC Article
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.
Homsy J, Zaidi S, Shen Y, Ware JS, Samocha KE, Karczewski KJ, DePalma SR, McKean D, Wakimoto H, Gorham J, Jin SC, Deanfield J, Giardini A, Porter GA Jr, Kim R, Bilguvar K, López-Giráldez F, Tikhonova I, Mane S, Romano-Adesman A, Qi H, Vardarajan B, Ma L, Daly M, Roberts AE, Russell MW, Mital S, Newburger JW, Gaynor JW, Breitbart RE, Iossifov I, Ronemus M, Sanders SJ, Kaltman JR, Seidman JG, Brueckner M, Gelb BD, Goldmuntz E, Lifton RP, Seidman CE, Chung WK
Science 2015 Dec 4;350(6265):1262-6. doi: 10.1126/science.aac9396. PMID: 26785492Free PMC Article

Diagnosis

Environmental and individual exposure and the risk of congenital anomalies: a review of recent epidemiological evidence.
Baldacci S, Gorini F, Santoro M, Pierini A, Minichilli F, Bianchi F
Epidemiol Prev 2018 May-Aug;42(3-4 Suppl 1):1-34. doi: 10.19191/EP18.3-4.S1.P001.057. PMID: 30066535
Nervous System Malformations.
Gaitanis J, Tarui T
Continuum (Minneap Minn) 2018 Feb;24(1, Child Neurology):72-95. doi: 10.1212/CON.0000000000000561. PMID: 29432238Free PMC Article
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.
Homsy J, Zaidi S, Shen Y, Ware JS, Samocha KE, Karczewski KJ, DePalma SR, McKean D, Wakimoto H, Gorham J, Jin SC, Deanfield J, Giardini A, Porter GA Jr, Kim R, Bilguvar K, López-Giráldez F, Tikhonova I, Mane S, Romano-Adesman A, Qi H, Vardarajan B, Ma L, Daly M, Roberts AE, Russell MW, Mital S, Newburger JW, Gaynor JW, Breitbart RE, Iossifov I, Ronemus M, Sanders SJ, Kaltman JR, Seidman JG, Brueckner M, Gelb BD, Goldmuntz E, Lifton RP, Seidman CE, Chung WK
Science 2015 Dec 4;350(6265):1262-6. doi: 10.1126/science.aac9396. PMID: 26785492Free PMC Article
Proboscis lateralis.
Martin S, Hogan E, Sorenson EP, Cohen-Gadol AA, Tubbs RS, Loukas M
Childs Nerv Syst 2013 Jun;29(6):885-91. Epub 2013 Jan 25 doi: 10.1007/s00381-012-1989-0. PMID: 23354442
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Therapy

The combined effect of short foot exercises and orthosis in symptomatic flexible flatfoot: a randomized controlled trial.
Elsayed W, Alotaibi S, Shaheen A, Farouk M, Farrag A
Eur J Phys Rehabil Med 2023 Jun;59(3):396-405. Epub 2023 Mar 29 doi: 10.23736/S1973-9087.23.07846-2. PMID: 36988565Free PMC Article
Mechanical vestibular stimulation versus traditional balance exercises in children with Down syndrome.
Nahla IM, El-Sayed SE, Ragaa AE, El Ghafar AEHAA
Afr Health Sci 2022 Mar;22(1):377-383. doi: 10.4314/ahs.v22i1.46. PMID: 36032439Free PMC Article
Foot orthoses for treating paediatric flat feet.
Evans AM, Rome K, Carroll M, Hawke F
Cochrane Database Syst Rev 2022 Jan 26;1(1):CD006311. doi: 10.1002/14651858.CD006311.pub4. PMID: 35080267Free PMC Article
Foot orthoses for treating paediatric flat feet.
Evans AM, Rome K, Carroll M, Hawke F
Cochrane Database Syst Rev 2022 Jan 14;1(1):CD006311. doi: 10.1002/14651858.CD006311.pub3. PMID: 35029841Free PMC Article
Neural tube defects.
Greene ND, Copp AJ
Annu Rev Neurosci 2014;37:221-42. doi: 10.1146/annurev-neuro-062012-170354. PMID: 25032496Free PMC Article

Prognosis

Nervous System Malformations.
Gaitanis J, Tarui T
Continuum (Minneap Minn) 2018 Feb;24(1, Child Neurology):72-95. doi: 10.1212/CON.0000000000000561. PMID: 29432238Free PMC Article
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.
Homsy J, Zaidi S, Shen Y, Ware JS, Samocha KE, Karczewski KJ, DePalma SR, McKean D, Wakimoto H, Gorham J, Jin SC, Deanfield J, Giardini A, Porter GA Jr, Kim R, Bilguvar K, López-Giráldez F, Tikhonova I, Mane S, Romano-Adesman A, Qi H, Vardarajan B, Ma L, Daly M, Roberts AE, Russell MW, Mital S, Newburger JW, Gaynor JW, Breitbart RE, Iossifov I, Ronemus M, Sanders SJ, Kaltman JR, Seidman JG, Brueckner M, Gelb BD, Goldmuntz E, Lifton RP, Seidman CE, Chung WK
Science 2015 Dec 4;350(6265):1262-6. doi: 10.1126/science.aac9396. PMID: 26785492Free PMC Article
Paediatric pancreatitis.
Pohl JF, Uc A
Curr Opin Gastroenterol 2015 Sep;31(5):380-6. doi: 10.1097/MOG.0000000000000197. PMID: 26181572Free PMC Article
Electrodiagnosis of polyneuropathy.
Johnsen B, Fuglsang-Frederiksen A
Neurophysiol Clin 2000 Dec;30(6):339-51. doi: 10.1016/s0987-7053(00)00237-9. PMID: 11191927
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Clinical prediction guides

KMT2D Deficiency Causes Sensorineural Hearing Loss in Mice and Humans.
Kalinousky AJ, Luperchio TR, Schrode KM, Harris JR, Zhang L, DeLeon VB, Fahrner JA, Lauer AM, Bjornsson HT
Genes (Basel) 2023 Dec 28;15(1) doi: 10.3390/genes15010048. PMID: 38254937Free PMC Article
Spontaneous, Voluntary, and Reflex Blinking in Clinical Practice.
Valls-Sole J
J Clin Neurophysiol 2019 Nov;36(6):415-421. doi: 10.1097/WNP.0000000000000561. PMID: 31688324
Arrhythmogenic right ventricular dysplasia/cardiomyopathy: an electrocardiogram-based review.
Nunes de Alencar Neto J, Baranchuk A, Bayés-Genís A, Bayés de Luna A
Europace 2018 Jun 1;20(FI1):f3-f12. doi: 10.1093/europace/eux202. PMID: 29272363
Neurosteroids: beginning of the story.
Baulieu EE, Robel P, Schumacher M
Int Rev Neurobiol 2001;46:1-32. doi: 10.1016/s0074-7742(01)46057-0. PMID: 11599297
Pancreas divisum.
Varshney S, Johnson CD
Int J Pancreatol 1999 Apr;25(2):135-41. doi: 10.1385/IJGC:25:2:135. PMID: 10360226

Recent systematic reviews

Antibiotics for acute otitis media in children.
Venekamp RP, Sanders SL, Glasziou PP, Rovers MM
Cochrane Database Syst Rev 2023 Nov 15;11(11):CD000219. doi: 10.1002/14651858.CD000219.pub5. PMID: 37965923Free PMC Article
Laser therapy for treating hypertrophic and keloid scars.
Leszczynski R, da Silva CA, Pinto ACPN, Kuczynski U, da Silva EM
Cochrane Database Syst Rev 2022 Sep 26;9(9):CD011642. doi: 10.1002/14651858.CD011642.pub2. PMID: 36161591Free PMC Article
Physical therapy treatment of hypermobile Ehlers-Danlos syndrome: A systematic review.
Reychler G, De Backer MM, Piraux E, Poncin W, Caty G
Am J Med Genet A 2021 Oct;185(10):2986-2994. Epub 2021 Jun 19 doi: 10.1002/ajmg.a.62393. PMID: 34145717
Congenital Zika syndrome: A systematic review.
Freitas DA, Souza-Santos R, Carvalho LMA, Barros WB, Neves LM, Brasil P, Wakimoto MD
PLoS One 2020;15(12):e0242367. Epub 2020 Dec 15 doi: 10.1371/journal.pone.0242367. PMID: 33320867Free PMC Article
Swaddling: a systematic review.
van Sleuwen BE, Engelberts AC, Boere-Boonekamp MM, Kuis W, Schulpen TW, L'Hoir MP
Pediatrics 2007 Oct;120(4):e1097-106. doi: 10.1542/peds.2006-2083. PMID: 17908730

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