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Adult Burkitt Lymphoma

MedGen UID:
124506
•Concept ID:
C0278764
•
Neoplastic Process
Synonym: Adult Burkitt's Lymphoma

Definition

A Burkitt lymphoma occurring in adults. [from NCI]

Professional guidelines

PubMed

Treatment outcomes of adult Burkitt lymphoma: results with a modified LMB protocol in Brazil and feasibility of outpatient administration.
Silva Junior WFD, Rosa LID, Belesso M, Lage LAPC, Rocha V, Pereira J
J Chemother 2018 Oct-Dec;30(6-8):375-379. doi: 10.1080/1120009X.2018.1535771. PMID: 30663548
Adult Burkitt lymphoma: advances in diagnosis and treatment.
Aldoss IT, Weisenburger DD, Fu K, Chan WC, Vose JM, Bierman PJ, Bociek RG, Armitage JO
Oncology (Williston Park) 2008 Nov 30;22(13):1508-17. PMID: 19133605
Treatment advances in adult Burkitt lymphoma and leukemia.
Kasamon YL, Swinnen LJ
Curr Opin Oncol 2004 Sep;16(5):429-35. doi: 10.1097/00001622-200409000-00003. PMID: 15314510

Recent clinical studies

Etiology

Targeted therapy in Burkitt lymphoma: Small molecule inhibitors under investigation.
Atallah-Yunes SA, Habermann TM, Khurana A
Br J Haematol 2024 Jun;204(6):2165-2172. Epub 2024 Apr 5 doi: 10.1111/bjh.19425. PMID: 38577716
Multicenter Study of Risk-Adapted Therapy With Dose-Adjusted EPOCH-R in Adults With Untreated Burkitt Lymphoma.
Roschewski M, Dunleavy K, Abramson JS, Powell BL, Link BK, Patel P, Bierman PJ, Jagadeesh D, Mitsuyasu RT, Peace D, Watson PR, Hanna WT, Melani C, Lucas AN, Steinberg SM, Pittaluga S, Jaffe ES, Friedberg JW, Kahl BS, Little RF, Bartlett NL, Fanale MA, Noy A, Wilson WH
J Clin Oncol 2020 Aug 1;38(22):2519-2529. Epub 2020 May 26 doi: 10.1200/JCO.20.00303. PMID: 32453640Free PMC Article
The role of hematopoietic SCT in adult Burkitt lymphoma.
Ahmed SO, Sureda A, Aljurf M
Bone Marrow Transplant 2013 May;48(5):617-29. Epub 2012 Jul 30 doi: 10.1038/bmt.2012.129. PMID: 22858508
Treatment advances in adult Burkitt lymphoma and leukemia.
Kasamon YL, Swinnen LJ
Curr Opin Oncol 2004 Sep;16(5):429-35. doi: 10.1097/00001622-200409000-00003. PMID: 15314510
Chromosomal abnormalities in adult non-endemic Burkitt's lymphoma and leukemia: 22 new reports and a review of 148 cases from the literature.
Kornblau SM, Goodacre A, Cabanillas F
Hematol Oncol 1991 Mar-Apr;9(2):63-78. doi: 10.1002/hon.2900090202. PMID: 1869243

Diagnosis

Burkitt lymphoma - no impact of HIV status on outcomes with rituximab-based chemoimmunotherapy.
Tan JY, Qiu TY, Chiang J, Tan YH, Yang VS, Chang EWY, Poon E, Somasundaram N, Farid M, Tao M, Lim ST, Chan JY
Leuk Lymphoma 2023 Mar;64(3):586-596. Epub 2022 Feb 19 doi: 10.1080/10428194.2022.2027402. PMID: 35188049
Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets.
Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican T, Lachel CM, Yu J, Ferro R, Eldorghamy N, Greiner TC, Vose J, Weisenburger DD, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, Jaffe ES, Braziel RM, Siebert R, Miles RR, Dave S, Reddy A, Delabie J, Staudt LM, Song JY, McKeithan TW, Fu K, Green M, Chan WC, Iqbal J
Blood 2017 Oct 19;130(16):1819-1831. Epub 2017 Aug 11 doi: 10.1182/blood-2017-02-767335. PMID: 28801451Free PMC Article
Adult Burkitt lymphoma originating in the sphenoid sinus: case report and review of the literature.
Chennupati SK, Govindaraj S, Setzen G, Chiu AG
Ear Nose Throat J 2009 Jul;88(7):E07. PMID: 19623516
Treatment advances in adult Burkitt lymphoma and leukemia.
Kasamon YL, Swinnen LJ
Curr Opin Oncol 2004 Sep;16(5):429-35. doi: 10.1097/00001622-200409000-00003. PMID: 15314510
Chromosomal abnormalities in adult non-endemic Burkitt's lymphoma and leukemia: 22 new reports and a review of 148 cases from the literature.
Kornblau SM, Goodacre A, Cabanillas F
Hematol Oncol 1991 Mar-Apr;9(2):63-78. doi: 10.1002/hon.2900090202. PMID: 1869243

Therapy

Targeted therapy in Burkitt lymphoma: Small molecule inhibitors under investigation.
Atallah-Yunes SA, Habermann TM, Khurana A
Br J Haematol 2024 Jun;204(6):2165-2172. Epub 2024 Apr 5 doi: 10.1111/bjh.19425. PMID: 38577716
Burkitt lymphoma - no impact of HIV status on outcomes with rituximab-based chemoimmunotherapy.
Tan JY, Qiu TY, Chiang J, Tan YH, Yang VS, Chang EWY, Poon E, Somasundaram N, Farid M, Tao M, Lim ST, Chan JY
Leuk Lymphoma 2023 Mar;64(3):586-596. Epub 2022 Feb 19 doi: 10.1080/10428194.2022.2027402. PMID: 35188049
Chimeric Antigen Receptor-Modified T Cell Immunotherapy for Relapsed and Refractory Adult Burkitt Lymphoma.
Wu J, Cao Y, Zhang Q, Liu W, Zhou X, Ming X, Meng F, Zhang Y, Li C, Huang L, Wei J, Zheng M, Zhang S, Zhang T, Zhu X, Wang N, Wang J, Wang G, Zhou J, Liu B, Xiao Y
Front Immunol 2022;13:879983. Epub 2022 May 20 doi: 10.3389/fimmu.2022.879983. PMID: 35669773Free PMC Article
Multicenter Study of Risk-Adapted Therapy With Dose-Adjusted EPOCH-R in Adults With Untreated Burkitt Lymphoma.
Roschewski M, Dunleavy K, Abramson JS, Powell BL, Link BK, Patel P, Bierman PJ, Jagadeesh D, Mitsuyasu RT, Peace D, Watson PR, Hanna WT, Melani C, Lucas AN, Steinberg SM, Pittaluga S, Jaffe ES, Friedberg JW, Kahl BS, Little RF, Bartlett NL, Fanale MA, Noy A, Wilson WH
J Clin Oncol 2020 Aug 1;38(22):2519-2529. Epub 2020 May 26 doi: 10.1200/JCO.20.00303. PMID: 32453640Free PMC Article
The role of hematopoietic SCT in adult Burkitt lymphoma.
Ahmed SO, Sureda A, Aljurf M
Bone Marrow Transplant 2013 May;48(5):617-29. Epub 2012 Jul 30 doi: 10.1038/bmt.2012.129. PMID: 22858508

Prognosis

Targeted therapy in Burkitt lymphoma: Small molecule inhibitors under investigation.
Atallah-Yunes SA, Habermann TM, Khurana A
Br J Haematol 2024 Jun;204(6):2165-2172. Epub 2024 Apr 5 doi: 10.1111/bjh.19425. PMID: 38577716
Chimeric Antigen Receptor-Modified T Cell Immunotherapy for Relapsed and Refractory Adult Burkitt Lymphoma.
Wu J, Cao Y, Zhang Q, Liu W, Zhou X, Ming X, Meng F, Zhang Y, Li C, Huang L, Wei J, Zheng M, Zhang S, Zhang T, Zhu X, Wang N, Wang J, Wang G, Zhou J, Liu B, Xiao Y
Front Immunol 2022;13:879983. Epub 2022 May 20 doi: 10.3389/fimmu.2022.879983. PMID: 35669773Free PMC Article
Multicenter Study of Risk-Adapted Therapy With Dose-Adjusted EPOCH-R in Adults With Untreated Burkitt Lymphoma.
Roschewski M, Dunleavy K, Abramson JS, Powell BL, Link BK, Patel P, Bierman PJ, Jagadeesh D, Mitsuyasu RT, Peace D, Watson PR, Hanna WT, Melani C, Lucas AN, Steinberg SM, Pittaluga S, Jaffe ES, Friedberg JW, Kahl BS, Little RF, Bartlett NL, Fanale MA, Noy A, Wilson WH
J Clin Oncol 2020 Aug 1;38(22):2519-2529. Epub 2020 May 26 doi: 10.1200/JCO.20.00303. PMID: 32453640Free PMC Article
The role of hematopoietic SCT in adult Burkitt lymphoma.
Ahmed SO, Sureda A, Aljurf M
Bone Marrow Transplant 2013 May;48(5):617-29. Epub 2012 Jul 30 doi: 10.1038/bmt.2012.129. PMID: 22858508
Treatment advances in adult Burkitt lymphoma and leukemia.
Kasamon YL, Swinnen LJ
Curr Opin Oncol 2004 Sep;16(5):429-35. doi: 10.1097/00001622-200409000-00003. PMID: 15314510

Clinical prediction guides

Burkitt lymphoma - no impact of HIV status on outcomes with rituximab-based chemoimmunotherapy.
Tan JY, Qiu TY, Chiang J, Tan YH, Yang VS, Chang EWY, Poon E, Somasundaram N, Farid M, Tao M, Lim ST, Chan JY
Leuk Lymphoma 2023 Mar;64(3):586-596. Epub 2022 Feb 19 doi: 10.1080/10428194.2022.2027402. PMID: 35188049
Chimeric Antigen Receptor-Modified T Cell Immunotherapy for Relapsed and Refractory Adult Burkitt Lymphoma.
Wu J, Cao Y, Zhang Q, Liu W, Zhou X, Ming X, Meng F, Zhang Y, Li C, Huang L, Wei J, Zheng M, Zhang S, Zhang T, Zhu X, Wang N, Wang J, Wang G, Zhou J, Liu B, Xiao Y
Front Immunol 2022;13:879983. Epub 2022 May 20 doi: 10.3389/fimmu.2022.879983. PMID: 35669773Free PMC Article
Multicenter Study of Risk-Adapted Therapy With Dose-Adjusted EPOCH-R in Adults With Untreated Burkitt Lymphoma.
Roschewski M, Dunleavy K, Abramson JS, Powell BL, Link BK, Patel P, Bierman PJ, Jagadeesh D, Mitsuyasu RT, Peace D, Watson PR, Hanna WT, Melani C, Lucas AN, Steinberg SM, Pittaluga S, Jaffe ES, Friedberg JW, Kahl BS, Little RF, Bartlett NL, Fanale MA, Noy A, Wilson WH
J Clin Oncol 2020 Aug 1;38(22):2519-2529. Epub 2020 May 26 doi: 10.1200/JCO.20.00303. PMID: 32453640Free PMC Article
Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets.
Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican T, Lachel CM, Yu J, Ferro R, Eldorghamy N, Greiner TC, Vose J, Weisenburger DD, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, Jaffe ES, Braziel RM, Siebert R, Miles RR, Dave S, Reddy A, Delabie J, Staudt LM, Song JY, McKeithan TW, Fu K, Green M, Chan WC, Iqbal J
Blood 2017 Oct 19;130(16):1819-1831. Epub 2017 Aug 11 doi: 10.1182/blood-2017-02-767335. PMID: 28801451Free PMC Article
The role of hematopoietic SCT in adult Burkitt lymphoma.
Ahmed SO, Sureda A, Aljurf M
Bone Marrow Transplant 2013 May;48(5):617-29. Epub 2012 Jul 30 doi: 10.1038/bmt.2012.129. PMID: 22858508

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